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Gene · 10021

Papers1,759

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Genetic loci responsible for atrioventricular block in children.Front Cell Dev Biol202642798645PubTator, text miningPubMed
The proximal N terminus of IRAG is required for potentiation of HCN4 channels.J Gen Physiol202642720667PubTator, text miningPubMed
Temperature dependence of HCN channel kinetics: A systematic comparison across mammalian isoforms and species.Exp Physiol202642669770PubTator, text miningPubMed
Comparative transcriptomics analysis of histone deacetylases, transcription factors, and ion channel genes in human iPSC-cardiomyocytes vs. the adult human heart.J Precis Med (Amst)202642644057PubTator, text miningPubMed
The HCN4 channel modulates external tufted cell burst firing.J Neurophysiol202642606887PubTator, text miningPubMed
The Hyperpolarization-Activated, Cyclic-Nucleotide (HCN) Ion Channel Inhibitors as Potential Therapy for Pain, CNS Disorders, Psychiatric Disorders, and Tinnitus.ACS Med Chem Lett202642445009PubTator, text miningPubMed
Aberrant TMPRSS6-Protease Regulation of Disease Mutant HCN4-KCNE1 Channel Complex Depends on the KCNE1-G38S Polymorphism.Arch Pharm (Weinheim)202642424558PubTator, text miningPubMed
Current Topics of Progressive Cardiac Conduction Disease.J Arrhythm202642368294PubTator, text miningPubMed
Rare Truncating HAND2 Variants Predispose to Atrial Fibrillation.Genes (Basel)202642353861PubTator, text miningPubMed
Distinct effects of disease-associated mutations in the proximal C-linker on negatively cooperative binding of cyclic nucleotides to the human HCN4 channel.Biochem Cell Biol202642241720PubTator, text miningPubMed
Phenotypic Effects of a Novel HCN4 c.1494C>A (p.Ser498Arg) Sequence Variation.JACC Case Rep202642233914PubTator, text miningPubMed
Endurance exercise remodels pulmonary vein sleeve myocytes and promotes a proarrhythmic atrial substrate.Eur Heart J202642178147PubTator, text miningPubMed
The proximal N-terminus of IRAG is required for potentiation of HCN4 channels.bioRxiv202642079162PubTator, text miningPubMed
Bradycardia and left ventricular noncompaction associated with a novel HCN4 p.Ser474Arg variant.HeartRhythm Case Rep202642028092PubTator, text miningPubMed
HCN1 is a primary HCN Pacemaker Channel in Neurons.Nat Commun202642026039PubTator, text miningPubMed
Multidisciplinary Management Enables Safe Return to Sports in a Pediatric Sudden Cardiac Death Survivor.JACC Case Rep202641906581PubTator, text miningPubMed
Gene Variants Associated With Individual Sensitivity for Taste Changes After the COVID-19 Infection.Biomed Res Int202641906187PubTator, text miningPubMed
Gene expression of the HCN family in rats with pilocarpine-induced epilepsy and in human hippocampal and cortical tissue.Brain Res202641903877PubTator, text miningPubMed
Spatial remodeling of the tumor immune microenvironment in hepatocellular carcinoma with cirrhosis driven by Treg-CD8⁺T cell crosstalk via the SPP1-ITGA4 axis.Transl Oncol202641855857PubTator, text miningPubMed
Alteplase and Angioedema: Can Clinical Exome Sequencing Redefine the Paradigm?Life (Basel)202641752838PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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