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Gene · 10075

Papers1,859

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
CircLOC375190 Promotes Mitochondrial Dysfunction and Ferroptosis in Neurons after Stroke by Stabilizing HUWE1 Through Interaction-Induced Ubiquitination and Degradation of IGF2BP2.Appl Biochem Biotechnol202641670946PubTator, text miningPubMed
Novel HUWE1-Related Neurodevelopmental Disorder: Genotypic and Phenotypic Expansion.Int J Dev Neurosci202641664155PubTator, text miningPubMed
Chronobiology of neurotropic viruses: rhythmic viral entry and arrhythmic host clocks.Cell Discov202641663379PubTator, text miningPubMed
HUWE1 regulates mitophagy to protect dopaminergic neurons from 6-OHDA- and MPP⁺-induced neurotoxicity.Cell Biol Toxicol202641639490PubTator, text miningPubMed
Kitasamycin overcomes ferroptosis and immunotherapy resistance by targeting the HUWE1-NCOA4-FTH1 axis.Autophagy202641612599PubTator, text miningPubMed
Guardian ubiquitin E3 ligases target cancer-associated APOBEC3 deaminases for degradation to promote human genome integrity.Nat Commun202641554709PubTator, text miningPubMed
Multi-center multi-omics integration predicts individualized prognosis in medullary thyroid carcinoma.Nat Commun202641535264PubTator, text miningPubMed
PARG regulates the proteasomal degradation of TARG1.Cell Rep202641499238PubTator, text miningPubMed
Multi-pathway therapeutics in colorectal cancer: targeting EMT, CSCs, and non-apoptotic cell death for drug resistance reversal.J Drug Target202641367286PubTator, text miningPubMed
Phenotypic And Molecular Characteristics of Three Additional Patients With HUWE1-Related X-Linked Intellectual Disability.Balkan J Med Genet202542147991PubTator, text miningPubMed
Lysine deficiency within a conserved lysine desert is critical for EEL-1/HUWE1 to support ubiquitin proteasome system function.bioRxiv202541509443PubTator, text miningPubMed
The cytoskeletal protein smoothelin maintains homologous recombination repair by stabilizing RAD51 in an HUWE1-dependent manner in colorectal cancer.Acta Pharm Sin B202541477349PubTator, text miningPubMed
[Pathogenicity analysis and genetic counseling for a hemizygous c.1042-10G>C variant of SLC9A7 gene].Zhonghua Yi Xue Yi Chuan Xue Za Zhi202541451488PubTator, text miningPubMed
Disrupted genes and pathways in schizophrenia: a robust analysis of the brain and blood.BMC Psychiatry202541422210PubTator, text miningPubMed
Physiological α-synuclein S129 phosphorylation mediates postsynaptic and nuclear interactions in the human brain.bioRxiv202541394717PubTator, text miningPubMed
O-GlcNAcylation of DDB1 at Ser-764 by OGT promotes cancer cell stemness in colorectal cancer through increased polyubiquitination of p53.Sci Rep202541331036PubTator, text miningPubMed
Enrichment-Free, Targeted Covalent Drug Discovery in Live Cells.ACS Chem Biol202541251312PubTator, text miningPubMed
[Clinical and genetic characteristics of X-linked intellectual disability associated with HUWE1 gene variants].Zhonghua Er Ke Za Zhi202541233135PubTator, text miningPubMed
Alternative Promoters Drive Transcriptomic Reprogramming and Prognostic Stratification in TNBC.NPJ Syst Biol Appl202541168177PubTator, text miningPubMed
Drug ubiquitination: an unwelcome mode of action or a novel modality.Trends Biochem Sci202541162202PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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