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Gene · 11274

Papers1,718

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A novel stop-loss variant in ISG15 causes C-terminal dysfunction and impairs USP18-mediated negative feedback.Front Immunol202642824448PubTator, text miningPubMed
Sequential exposure to histological chorioamnionitis and postnatal hyperoxia alters gene expression in cord blood monocytes.Front Pediatr202642812615PubTator, text miningPubMed
Organelle-centered ISG15 biology: distinguishing covalent ISGylation from interferon-associated responses.Front Immunol202642757191PubTator, text miningPubMed
piRNA-46403 Promotes Sertoli Cell Ferroptosis via Disrupting m5C-dependent USP18 mRNA Stabilization in Varicocele-mediated Infertility.Int J Biol Sci202642695002PubTator, text miningPubMed
Regulators of interferon-responsive microglia uncovered by Genome-wide CRISPRi screening.NPJ Dement202642694111PubTator, text miningPubMed
Clinicopathological significance and exploratory prognostic modeling of USP18 and YBX3 expression in clear cell renal cell carcinoma: a retrospective Chinese cohort study.Front Oncol202642614232PubTator, text miningPubMed
SR-A3 Promotes USP18-Mediated deISGylation of STING to Protect Against Myocardial Ischemia-Reperfusion Injury.Adv Sci (Weinh)202642606110PubTator, text miningPubMed
Transcription factor EN1 governs a lipogenic USP18-ACLY axis to drive bladder cancer malignancy.Oncogene202642521834PubTator, text miningPubMed
Familial pulmonary alveolar proteinosis and type I interferonopathy by mutation of STAT2 (TIMS2).J Exp Med202642461263PubTator, text miningPubMed
Repeated aminoglycoside exposure activates interferon-stimulated genes in human renal proximal tubular models.Arch Toxicol202642446670PubTator, text miningPubMed
Understanding protein ISGylation, a multifaceted posttranslational modification.Cell Chem Biol202642442365PubTator, text miningPubMed
USP18 regulates skeletal muscle regeneration independently of its deISGylation activity.Biochim Biophys Acta Mol Basis Dis202642431519PubTator, text miningPubMed
USP18-driven macrophage M2 polarization through fatty acid β-oxidation inhibits immune responses induced by RSV infection.J Infect Dev Ctries202642430541PubTator, text miningPubMed
ISGylation-mediated stabilization of CYP4Z1 fuels breast cancer initiation and progression.Exp Mol Med202642393313PubTator, text miningPubMed
USP18 Impacts Cisplatin Resistance in Ovarian Cancer Cells by Modulating DNA Repair.Int J Biol Sci202642328450PubTator, text miningPubMed
USP24 is a cross-reactive DUB targeting MOV10 to regulate IFN-I production.Nat Commun202642321163PubTator, text miningPubMed
Gene expression profiling of dendritic cell tolerance dysfunction in women with systemic lupus erythematosus.Front Immunol202642311689PubTator, text miningPubMed
Identification of macrophage polarization-related genes for esophageal cancer risk: a multi-omics Mendelian randomization analysis.Clin Epigenetics202642251386PubTator, text miningPubMed
Multi-omics and machine learning uncover the MX1-ISG15-STAT1 synergistic axis as the core interferon signature in systemic lupus erythematosus and identify herbal-derived multi-target therapeutic candidates.
Comput Biol Chem202642241839PubTator, text miningPubMed
WITHDRAWN: USP18-FTO axis activates PI3K-AKT signaling to drive endometrial carcinoma progression.Int J Biol Macromol202642229644PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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