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USP18: ubiquitin specific peptidase 18
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Gene · 11274

Papers1,718

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

21 to 40 of 1,718

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TitleJournalYearPMIDFound bySource
USP18-stabilized ELF3 drives glycolysis and malignant progression in lung adenocarcinoma.Acta Biochim Biophys Sin (Shanghai)202642212622PubTator, text miningPubMed
STAT2 R148 variant: A 16th-century founder mutation and clinical response to high-dose JAK inhibitor therapy.J Hum Immun202642212111PubTator, text miningPubMed
Lactylation of PTBP1 drives a pro-apoptotic positive feedback loop in microglia following oxygen-glucose deprivation/reoxygenation-induced injury.Cell Death Dis202642209452PubTator, text miningPubMed
BRCA1 deficiency induces NFκB-dependent type-I interferon signaling in fallopian tube epithelial cells.Neoplasia202642190606PubTator, text miningPubMed
ABHD11-AS1 Suppresses Colorectal Cancer Progression by Disrupting EIF4E-mediated POU2F1 Ubiquitination.Int J Biol Sci202642157946PubTator, text miningPubMed
Derivation and characterization of ubiquitin-specific protease 18 inhibitors.JCI Insight202642154529PubTator, text miningPubMed
Aptamer-Targeted PrPC Drives Colorectal Cancer Metastasis via a LYN-STAT3 Complex and Enables Liquid Biopsy Detection.Adv Sci (Weinh)202642154443PubTator, text miningPubMed
ISG15/ISGylation in central nervous system diseases: molecular mechanisms and therapeutic targeting.Biochem Pharmacol202642140444PubTator, text miningPubMed
Single-cell RNA-seq reveals a persistent interferon signature in immune cells from systemic lupus erythematosus patients with high versus low polygenic risk scores despite antimalarial treatment.J Autoimmun202642119160PubTator, text miningPubMed
USP18 promotes clear cell renal cell carcinoma progression by regulating the ubiquitination and stability of YBX3.iScience202642111157PubTator, text miningPubMed
Cinnamaldehyde Ameliorates Ischemic Heart Failure by Targeting USP18 to Inhibit [Formula: see text]-Adrenergic Receptor Ubiquitination and Suppress TAK1/NF-[Formula: see text]B Signaling Pathway.Am J Chin Med202642100837PubTator, text miningPubMed
Dissecting ARL15 Function in Rheumatoid Arthritis: Insights From Ex Vivo and in Vitro Synovial Fibroblast Models.Int J Rheum Dis202642087570PubTator, text miningPubMed
Retinoic Acid-inducible Gene-I Increases Interferon-stimulated Gene 15 Expression in Human Renal Proximal Tubule Epithelial Cells.In Vivo202642049405PubTator, text miningPubMed
[Interferon-α induces disulfidptosis occurrence in human liver cancer cells].Zhonghua Gan Zang Bing Za Zhi202642036226PubTator, text miningPubMed
Redox-triggered USP18 confers cisplatin resistance in ovarian cancer by selectively activating a non-canonical FSP1-dependent ferroptosis escape pathway.Redox Biol202642030646PubTator, text miningPubMed
Post-translational Modification that Shines in the Age of Viruses: ISGylation from a Structural Perspective.Curr Protein Pept Sci202642003196PubTator, text miningPubMed
ISG15-USP18 signaling restrains viperin-dependent metabolic antiviral restriction.bioRxiv202641959182PubTator, text miningPubMed
USP18 exacerbates myocardial I/R injury by inhibiting Parkin mitophagy through the deubiquitinase PTEN-L.Mil Med Res202641953055PubTator, text miningPubMed
Recurrent and Non-Recurrent Copy Number Variants in Native Americans and a Cosmopolitan Sample in Relation to Alcohol Use Disorder and Other Psychiatric Diseases.Mol Neurobiol202641866456PubTator, text miningPubMed
USP18 ameliorates atherosclerosis through inhibiting the activation of TAK1.Int Immunopharmacol202641865455PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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