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Gene · 1146

CHRNG: cholinergic receptor nicotinic gamma subunit

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CHRNG: cholinergic receptor nicotinic gamma subunit. Genes, record 1146. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1146

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Gene

Symbol
CHRNG
HGNC
Name
cholinergic receptor nicotinic gamma subunit
HGNC
NCBI Gene ID
1146
NCBI Gene
HGNC ID
HGNC:1967
HGNC
Ensembl
ENSG00000196811
NCBI Gene
Aliases
ACHRG
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P07510Acetylcholine receptor subunit gamma5170Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1441258P07510Espacenet
JP 2026004568 A2026-01-1441259P07510Espacenet
EP 4670794 A22025-12-3125P07510Espacenet
EP 4650780 A22025-11-1919751P07510Espacenet
JP 2025529142 A2025-09-04946P07510Espacenet
US 12371689 B22025-07-29946P07510Espacenet
JP 2025517970 A2025-06-1219751P07510Espacenet
EP 4551941 A22025-05-1447P07510Espacenet
US 12011480 B22024-06-1825P07510Espacenet
US 11446398 B22022-09-2015086P07510Espacenet

1 to 10 of 28

See all 28 patents

Drugs28

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ATRACURIUMCHEMBL1360Muscle-type nicotinic acetylcholine receptor antagonistANTAGONISTChEMBL
ATRACURIUM BESYLATECHEMBL1200527Muscle-type nicotinic acetylcholine receptor antagonistANTAGONISTChEMBL
CISATRACURIUMCHEMBL1201248Muscle-type nicotinic acetylcholine receptor antagonistANTAGONISTChEMBL
CISATRACURIUM BESYLATECHEMBL1200641Muscle-type nicotinic acetylcholine receptor antagonistANTAGONISTChEMBL
DECAMETHONIUMCHEMBL1190Muscle-type nicotinic acetylcholine receptor partial agonistPARTIAL AGONISTChEMBL
DECAMETHONIUM BROMIDECHEMBL1134Muscle-type nicotinic acetylcholine receptor partial agonistPARTIAL AGONISTChEMBL
DOXACURIUMCHEMBL1237123Muscle-type nicotinic acetylcholine receptor antagonistANTAGONISTChEMBL
DOXACURIUM CHLORIDECHEMBL1237099Muscle-type nicotinic acetylcholine receptor antagonistANTAGONISTChEMBL
GALLAMINECHEMBL360055Muscle-type nicotinic acetylcholine receptor antagonistANTAGONISTChEMBL
GALLAMINE TRIETHIODIDECHEMBL1200993Muscle-type nicotinic acetylcholine receptor antagonistANTAGONISTChEMBL

1 to 10 of 28

See all 28 drugs

Trials47

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants275

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCHRNG papersNewest fiscal year
P50HD105351Boston Children's Hospital/HMS Intellectual and Developmental Disabilities Research Center22025
KL2TR001862Institutional Career Development Core12025
P01CA196569Statistical Methods for Integrative Genomics in Cancer12025
P01HL141084Multiscale Systems to Elucidate Susceptibility and Cardioprotective Mechanisms in Cardio-oncology12025
P20GM103427Nebraska Research Network in Functional Genomics12025
P20GM103446Delaware INBRE12025
P30AG021332Wake Forest Claude D. Pepper OAIC - Renewal12025
P30CA008748Cancer Center Support Grant12025
P30CA012197Cancer Center Support Grant12025
P30ES029067Texas A&M Center for Environmental Health Research (TiCER)12025

1 to 10 of 275Source NIH's project files

See all 275 nih grants

Papers297

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrating machine learning and pharmacogenomics for biomarker discovery, identification and prioritization of potential drug candidates in ovarian cancer.SAR QSAR Environ Res202642253090PubTator, text miningPubMed
Non-pterygium Escobar syndrome from compound-heterozygous CHRNG variants: genotype-phenotype insights.Hum Genome Var202641826296PubTator, text miningPubMed
Health risk analysis of micro-and nanoplastic exposure via the microbiota-gut-brain axis.Front Immunol202641789083PubTator, text miningPubMed
Immune checkpoint inhibitor-related pneumonitis: current advances and the putative role of mesenchymal stem cell therapy.Cell Death Dis202641633975PubTator, text miningPubMed
Single-nucleus RNA sequencing identifies a novel tenogenic heterologous differentiation in endometrial carcinosarcomas: implications for diagnosis and tumor classification.J Pathol202641537454PubTator, text miningPubMed
Biallelic CRELD1 variants cause severe muscle weakness and infantile epilepsy.Brain Commun202540980404PubTator, text miningPubMed
Dual molecular genetic diagnosis with combined malonic and methylmalonic aciduria (CMAMMA): implications of coexisting genetic disorders on clinical presentation.J Pediatr Endocrinol Metab202540960910PubTator, text miningPubMed
Persistent Inflammation, Maladaptive Remodeling, and Fibrosis in the Kidney Following Long COVID-like MHV-1 Mouse Model.Diseases202540863220PubTator, text miningPubMed
Fetal Akinesia/Hypokinesia and Arthrogryposis of Neuromuscular Origin: Etiologic Groups, Genetics, and Phenotypic Spectrum.Ann Clin Transl Neurol202540443119PubTator, text miningPubMed
Trophic Factors in Muscle-Nerve Cross-Talk Signaling Augment Muscle Fiber and Motor Endplate Development.J Cell Physiol202539987522PubTator, text miningPubMed

1 to 10 of 297

See all 297 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1146

GET https://conductscience.org/api/genes/v1/1146/patents?page=2