Gene · 1282
COL4A1: collagen type IV alpha 1 chain
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. COL4A1: collagen type IV alpha 1 chain. Genes, record 1282. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1282
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P02462 | Collagen alpha-1(IV) chain | 1,669 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents78
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026067851 A | 2026-04-21 | 393 | P02462 | Espacenet |
| JP 2026042028 A | 2026-03-10 | 18 | P02462 | Espacenet |
| EP 4694927 A1 | 2026-02-18 | 26 | P02462 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 9692 | P02462 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 9950 | P02462 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 3290 | P02462 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 5952 | P02462 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 5952 | P02462 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 9950 | P02462 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 9692 | P02462 | Espacenet |
1 to 10 of 78
See all 78 patentsDrugs2
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials66
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT06169319 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE2 | ClinicalTrials.gov | |
| NCT06151197 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE3 | ClinicalTrials.gov | |
| NCT06065436 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | ClinicalTrials.gov | ||
| NCT05646602 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | ClinicalTrials.gov | ||
| NCT05254457 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE3 | ClinicalTrials.gov | |
| NCT05152173 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE2 | ClinicalTrials.gov | |
| NCT04874870 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE3 | ClinicalTrials.gov | |
| NCT04680156 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | ClinicalTrials.gov | ||
| NCT04496167 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE2 | 2023-09-13 | ClinicalTrials.gov |
| NCT04236635 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE2 | 2022-04-12 | ClinicalTrials.gov |
1 to 10 of 66
See all 66 trialsNIH grants2,514
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | COL4A1 papers | Newest fiscal year |
|---|---|---|---|
| R01EY019887 | Genetically testing mechanisms of ocular development and disease | 9 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 9 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 8 | 2025 |
| P30CA033572 | Cancer Center Support Grant | 7 | 2025 |
| R01DK018381 | Studies on the structure of basement membranes | 7 | 2025 |
| R01HL086694 | From GWAS loci to blood pressure genes, variants & mechanisms - Renewal | 6 | 2025 |
| R01NS017950 | Precursors of Stroke Incidence and Prognosis | 6 | 2025 |
| P30AG072975 | Rush Alzheimer's Disease Research Center | 5 | 2025 |
| P30CA062203 | Cancer Center Support Grant | 5 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 5 | 2025 |
1 to 10 of 2,514Source NIH's project files
See all 2,514 nih grantsPapers3,934
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
Unraveling tumor cell heterogeneity and epithelial-mesenchymal plasticity in gastric adenocarcinoma: an integrative multi-omics framework evaluating PVR/CD155 as a tumor cell-intrinsic EMT-associated target. | Front Immunol | 2026 | 42769440 | PubTator, text mining | PubMed |
| Fetal Intracranial Hemorrhage: What to Tell Expecting Parents? | Prenat Diagn | 2026 | 42762541 | PubTator, text mining | PubMed |
| Family partnership as a foundation for future international COL4A1 and COL4A2 research. | Dev Med Child Neurol | 2026 | 42748458 | PubTator, text mining | PubMed |
| The molecular landscape of hypertrophic cardiomyopathy across disease stages and genotypes. | Sci Transl Med | 2026 | 42748219 | PubTator, text mining | PubMed |
| A Rare Case of Gould Syndrome Presenting With Gastrointestinal Bleeding in a Pediatric Patient. | Cureus | 2026 | 42746649 | PubTator, text mining | PubMed |
| Single-cell and spatial transcriptomic profiling identifies a fibroblast-like endothelial state and the MDK-NCL signaling axis in prostate cancer microenvironment remodeling. | Transl Oncol | 2026 | 42669284 | PubTator, text mining | PubMed |
| Identification of Copy Number Variants as a Suspected Cause of Cerebral Small Vessel Disease. | Clin Genet | 2026 | 42661427 | PubTator, text mining | PubMed |
An Integrative Bioinformatics Framework Nominates Candidate Limbal Stem-Cell Exosome Cargo for Keratoconus by Coupling Corneal Transcriptomics, Disease-Gene Evidence and Extracellular-Vesicle Repositories. | Bioengineering (Basel) | 2026 | 42649743 | PubTator, text mining | PubMed |
| Exploring Matrix Stiffness-Related Gene in Periodontitis: A Comprehensive Multidataset Analysis. | Mediators Inflamm | 2026 | 42644235 | PubTator, text mining | PubMed |
| Quercetin and lupeol accelerate keratinocyte wound healing by dual modulation of GLP-1 receptor activity and stability. | Life Sci | 2026 | 42637031 | PubTator, text mining | PubMed |
1 to 10 of 3,934
See all 3,934 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1282
GET https://conductscience.org/api/genes/v1/1282/patents?page=2