Gene · 1284
COL4A2: collagen type IV alpha 2 chain
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. COL4A2: collagen type IV alpha 2 chain. Genes, record 1284. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1284
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P08572 | Collagen alpha-2(IV) chain | 1,712 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents115
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4705273 A2 | 2026-03-11 | 493 | P08572 | Espacenet |
| EP 4694927 A1 | 2026-02-18 | 27 | P08572 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 7778 | P08572 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 1175 | P08572 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 7863 | P08572 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 3294 | P08572 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 5953 | P08572 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 5953 | P08572 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 1175 | P08572 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 7863 | P08572 | Espacenet |
1 to 10 of 115
See all 115 patentsDrugs2
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials66
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT06169319 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE2 | ClinicalTrials.gov | |
| NCT06151197 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE3 | ClinicalTrials.gov | |
| NCT06065436 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | ClinicalTrials.gov | ||
| NCT05646602 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | ClinicalTrials.gov | ||
| NCT05254457 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE3 | ClinicalTrials.gov | |
| NCT05152173 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE2 | ClinicalTrials.gov | |
| NCT04874870 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE3 | ClinicalTrials.gov | |
| NCT04680156 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | ClinicalTrials.gov | ||
| NCT04496167 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE2 | 2023-09-13 | ClinicalTrials.gov |
| NCT04236635 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE2 | 2022-04-12 | ClinicalTrials.gov |
1 to 10 of 66
See all 66 trialsNIH grants1,809
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | COL4A2 papers | Newest fiscal year |
|---|---|---|---|
| R01DK018381 | Studies on the structure of basement membranes | 7 | 2025 |
| R01EY019887 | Genetically testing mechanisms of ocular development and disease | 7 | 2025 |
| R01HL086694 | From GWAS loci to blood pressure genes, variants & mechanisms - Renewal | 6 | 2025 |
| R01NS017950 | Precursors of Stroke Incidence and Prognosis | 6 | 2025 |
| ZIAHD002400 | The Role Of Subclinical Infection And Cytokines In Preterm Parturition | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| R01HL148239 | Multimodal genetic regulatory architecture of coronary artery disease | 5 | 2025 |
| UL1TR001881 | UCLA Clinical and Translational Science Institute | 5 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 4 | 2025 |
| P30DK017047 | Diabetes Research Center | 4 | 2025 |
1 to 10 of 1,809Source NIH's project files
See all 1,809 nih grantsPapers2,425
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Fetal Intracranial Hemorrhage: What to Tell Expecting Parents? | Prenat Diagn | 2026 | 42762541 | PubTator, text mining | PubMed |
| Family partnership as a foundation for future international COL4A1 and COL4A2 research. | Dev Med Child Neurol | 2026 | 42748458 | PubTator, text mining | PubMed |
| The molecular landscape of hypertrophic cardiomyopathy across disease stages and genotypes. | Sci Transl Med | 2026 | 42748219 | PubTator, text mining | PubMed |
| A Rare Case of Gould Syndrome Presenting With Gastrointestinal Bleeding in a Pediatric Patient. | Cureus | 2026 | 42746649 | PubTator, text mining | PubMed |
| Composition and Function of Decellularized Human Lung Extracellular Matrix from Congenital Pulmonary Airway Malformation. | J Clin Med | 2026 | 42739747 | PubTator, text mining | PubMed |
| Beyond hypoxia and ccRCC: the expanding universe of VHL novel targets and next-generation therapeutics. | Biomark Res | 2026 | 42717364 | PubTator, text mining | PubMed |
| Identification of Copy Number Variants as a Suspected Cause of Cerebral Small Vessel Disease. | Clin Genet | 2026 | 42661427 | PubTator, text mining | PubMed |
| Perinatal complications, mode of delivery, and neurological morbidity in children with COL4A1/A2 variants. | Dev Med Child Neurol | 2026 | 42605108 | PubTator, text mining | PubMed |
| Investigating the Cellular Activity and Differential Gene Expression of Human Astrocytes in Interaction with Protein Composite Nanofibers. | Neurochem Res | 2026 | 42599588 | PubTator, text mining | PubMed |
| Multigene panel analysis of connective tissue and vascular genes in patients with a bleeding disorder of unknown cause or a cerebrovascular event. | Res Pract Thromb Haemost | 2026 | 42568836 | PubTator, text mining | PubMed |
1 to 10 of 2,425
See all 2,425 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1284
GET https://conductscience.org/api/genes/v1/1284/patents?page=2