Gene · 1290
COL5A2: collagen type V alpha 2 chain
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. COL5A2: collagen type V alpha 2 chain. Genes, record 1290. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1290
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P05997 | Collagen alpha-2(V) chain | 1,499 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents85
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4705273 A2 | 2026-03-11 | 500 | P05997 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 9538 | P05997 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 9791 | P05997 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 3318 | P05997 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 5959 | P05997 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 5959 | P05997 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 9791 | P05997 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 9538 | P05997 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 3318 | P05997 | Espacenet |
| JP 2025013347 A | 2025-01-24 | 73 | P05997 | Espacenet |
1 to 10 of 85
See all 85 patentsDrugs2
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials66
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT06169319 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE2 | ClinicalTrials.gov | |
| NCT06151197 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE3 | ClinicalTrials.gov | |
| NCT06065436 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | ClinicalTrials.gov | ||
| NCT05646602 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | ClinicalTrials.gov | ||
| NCT05254457 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE3 | ClinicalTrials.gov | |
| NCT05152173 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE2 | ClinicalTrials.gov | |
| NCT04874870 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE3 | ClinicalTrials.gov | |
| NCT04680156 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | ClinicalTrials.gov | ||
| NCT04496167 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE2 | 2023-09-13 | ClinicalTrials.gov |
| NCT04236635 | COLLAGENASE CLOSTRIDIUM HISTOLYTICUM | PHASE2 | 2022-04-12 | ClinicalTrials.gov |
1 to 10 of 66
See all 66 trialsNIH grants1,169
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | COL5A2 papers | Newest fiscal year |
|---|---|---|---|
| UL1TR001863 | Yale Clinical and Translational Science Award | 8 | 2025 |
| P20GM103408 | Idaho INBRE Program | 4 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 4 | 2025 |
| ZIAHD002400 | The Role Of Subclinical Infection And Cytokines In Preterm Parturition | 4 | 2025 |
| P20GM103418 | Kansas IDeA Network of Biomedical Research Excellence 5 | 3 | 2025 |
| P30CA013148 | Comprehensive Cancer Center Support Grant | 3 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 3 | 2025 |
| P30CA091842 | Cancer Center Support Grant | 3 | 2025 |
| P30CA168524 | The University of Kansas Cancer Center | 3 | 2025 |
| P30ES025128 | Center for Human Health and the Environment (CHHE) | 3 | 2025 |
1 to 10 of 1,169Source NIH's project files
See all 1,169 nih grantsPapers2,039
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Effect of the unreported COL5A2 variant c.2499 + 4_2499 + 5insTAA on RNA splicing: Insights from minigene assays. | Clin Chim Acta | 2027 | 42594983 | PubTator, text mining | PubMed |
| Tumor FAK supports fibrillar collagen expression in ovarian cancer ascites. | Matrix Biol | 2026 | 42753930 | PubTator, text mining | PubMed |
| [Transcriptomic analysis of NT5E/CD73-related macrophage state remodeling in the maternal-fetal immune microenvironment of recurrent pregnancy loss]. | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | 2026 | 42750328 | PubTator, text mining | PubMed |
| METTL3-Mediated m6A Modification of COL5A2 Inhibits Ferroptosis Through an IGF2BP3-dependent Mechanism in Gastric Cancer. | Technol Cancer Res Treat | 2026 | 42663553 | PubTator, text mining | PubMed |
| CircRNA hsa_circ_0001946 promotes hypertrophic scar pathogenesis via the miR-514a-3p/COL5A2 axis. | Pathol Res Pract | 2026 | 42561881 | PubTator, text mining | PubMed |
| The therapy-induced senescence-associated secretory phenotype and epithelial-mesenchymal transition axis in ovarian cancer: molecular mechanisms and therapeutic opportunities. | Expert Opin Ther Targets | 2026 | 42528374 | PubTator, text mining | PubMed |
| Distinct Molecular Signature of Earlobe Keloids: Integrated Transcriptomic Analysis of Extracellualr Matrix, Metalloproteinase, and Metabolic Pathways. | Aesthetic Plast Surg | 2026 | 42414644 | PubTator, text mining | PubMed |
| Integrated transcriptomic and proteomic profiling in keloid tissue. | PeerJ | 2026 | 42369759 | PubTator, text mining | PubMed |
| Transcriptomic profiling of collagen gene expression in lung fibroblasts from patients with idiopathic pulmonary fibrosis. | Sarcoidosis Vasc Diffuse Lung Dis | 2026 | 42329017 | PubTator, text mining | PubMed |
| Collagen gene expression profiles predict recurrence and progression of DCIS to IDC. | Sci Rep | 2026 | 42288681 | PubTator, text mining | PubMed |
1 to 10 of 2,039
See all 2,039 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1290
GET https://conductscience.org/api/genes/v1/1290/patents?page=2