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Gene · 1306

COL15A1: collagen type XV alpha 1 chain

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. COL15A1: collagen type XV alpha 1 chain. Genes, record 1306. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1306

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Gene

Symbol
COL15A1
HGNC
Name
collagen type XV alpha 1 chain
HGNC
NCBI Gene ID
1306
NCBI Gene
HGNC ID
HGNC:2192
HGNC
Ensembl
ENSG00000204291
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P39059Collagen alpha-1(XV) chain1,3881Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-199559P39059Espacenet
EP 4641201 A22025-10-299815P39059Espacenet
JP 2025147176 A2025-10-063239P39059Espacenet
JP 2025529142 A2025-09-045937P39059Espacenet
US 12371689 B22025-07-295937P39059Espacenet
JP 2025517969 A2025-06-129815P39059Espacenet
JP 2025517970 A2025-06-129559P39059Espacenet
JP 2025032204 A2025-03-1126639P39059Espacenet
JP 2025028160 A2025-02-283239P39059Espacenet
KR 1020250010750 A2025-01-213239P39059Espacenet

1 to 10 of 28

See all 28 patents

Drugs2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
COLLAGENASE CLOSTRIDIUM HISTOLYTICUMCHEMBL2108709Collagen hydrolytic enzymeHYDROLYTIC ENZYMEChEMBL
OCRIPLASMINCHEMBL2095222Collagen hydrolytic enzymeHYDROLYTIC ENZYMEChEMBL

Trials66

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06169319COLLAGENASE CLOSTRIDIUM HISTOLYTICUMPHASE2ClinicalTrials.gov
NCT06151197COLLAGENASE CLOSTRIDIUM HISTOLYTICUMPHASE3ClinicalTrials.gov
NCT06065436COLLAGENASE CLOSTRIDIUM HISTOLYTICUMClinicalTrials.gov
NCT05646602COLLAGENASE CLOSTRIDIUM HISTOLYTICUMClinicalTrials.gov
NCT05254457COLLAGENASE CLOSTRIDIUM HISTOLYTICUMPHASE3ClinicalTrials.gov
NCT05152173COLLAGENASE CLOSTRIDIUM HISTOLYTICUMPHASE2ClinicalTrials.gov
NCT04874870COLLAGENASE CLOSTRIDIUM HISTOLYTICUMPHASE3ClinicalTrials.gov
NCT04680156COLLAGENASE CLOSTRIDIUM HISTOLYTICUMClinicalTrials.gov
NCT04496167COLLAGENASE CLOSTRIDIUM HISTOLYTICUMPHASE22023-09-13ClinicalTrials.gov
NCT04236635COLLAGENASE CLOSTRIDIUM HISTOLYTICUMPHASE22022-04-12ClinicalTrials.gov

1 to 10 of 66

See all 66 trials

NIH grants770

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCOL15A1 papersNewest fiscal year
P30CA016672Cancer Center Support Grant42025
P30EY001792P30 Core Grant for Vision Research42025
R01HL127349Genomic Analysis of Tissue and Cellular Heterogeneity in IPF42025
P30EY010572Ophthalmology Core Facility32025
UL1TR001863Yale Clinical and Translational Science Award32025
K12EY021475UIC K12 independent Clinical Vision Scientist Development Program22025
K24AR060297Scleroderma Twin Study and analysis of Estrogen in patients with dcSSc22025
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions22025
P30CA006927Comprehensive Cancer Center Program at Fox Chase22025
P30CA008748Cancer Center Support Grant22025

1 to 10 of 770Source NIH's project files

See all 770 nih grants

Papers844

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Peritoneal Fluid-Derived Small Extracellular Vesicle Proteins as Potential Biomarkers for Endometriosis: A Case-Control Study.BJOG202642786124PubTator, text miningPubMed
Exploring Matrix Stiffness-Related Gene in Periodontitis: A Comprehensive Multidataset Analysis.Mediators Inflamm202642644235PubTator, text miningPubMed
Prognostic and immunological value of LINC01615-related genes in kidney clear cell carcinoma: Integrated bioinformatics analysis and expression validation.Medicine (Baltimore)202642629666PubTator, text miningPubMed
Aberrant and ectopic cell populations in restrictive allograft syndrome after lung transplantation.Eur Respir J202642425730PubTator, text miningPubMed
Fibroblasts: a diverse population of cells balancing homeostasis, wound healing, regeneration, inflammation, fibrosis, and cancer across organs.JCI Insight202642417164PubTator, text miningPubMed
ILC2s regulate a fibroblast progenitor niche in the pancreas.Science202642391385PubTator, text miningPubMed
Collagen-producing eye cell atlas reveals distinct fibroblast fates in early injury vs. fibrotic subretinal disease.Proc Natl Acad Sci U S A202642361041PubTator, text miningPubMed
An integrated single-cell and spatial proteotranscriptomics atlas of fibroblast-driven immunoregulation within the human adult oral cavity.Cell Press Blue202642147490PubTator, text miningPubMed
An explainable ensemble machine learning framework for predicting cartilage biomechanical degradation from transcriptomic profiles: toward smart orthopedic device design.Front Bioeng Biotechnol202642147485PubTator, text miningPubMed
Microarray Analysis of Human Abdominal Aortic Aneurysm With Emphasis on Cardiovascular Genes Revealed Differentially Expressed Genes.In Vivo202642049434PubTator, text miningPubMed

1 to 10 of 844

See all 844 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1306

GET https://conductscience.org/api/genes/v1/1306/patents?page=2