Gene · 1592
CYP26A1: cytochrome P450 family 26 subfamily A member 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CYP26A1: cytochrome P450 family 26 subfamily A member 1. Genes, record 1592. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1592
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O43174 | Cytochrome P450 26A1 | 497 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents12
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 42903 | O43174 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 429 | O43174 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 429 | O43174 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 22032 | O43174 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 125003 | O43174 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 2807 | O43174 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 223338 | O43174 | Espacenet |
| JP 2017121241 A | 2017-07-13 | 223338 | O43174 | Espacenet |
| JP 2015516143 A | 2015-06-08 | 223338 | O43174 | Espacenet |
| US 8586006 B2 | 2013-11-19 | 56076 | O43174 | Espacenet |
1 to 10 of 12
See all 12 patentsDrugs1
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action |
|---|---|---|---|
| TALAROZOLE | CHEMBL459505 | Cytochrome P450 26A1 inhibitor | INHIBITOR |
Source ChEMBL
Trials4
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT00725439 | TALAROZOLE | PHASE2 | ClinicalTrials.gov | |
| NCT00725348 | TALAROZOLE | PHASE2 | ClinicalTrials.gov | |
| NCT00719121 | TALAROZOLE | PHASE1 | ClinicalTrials.gov | |
| NCT00716144 | TALAROZOLE | PHASE2 | 2018-01-29 | ClinicalTrials.gov |
NIH grants1,085
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CYP26A1 papers | Newest fiscal year |
|---|---|---|---|
| T32DK007247 | Diabetes, Obesity and Metabolism Training Program | 8 | 2025 |
| ZIABC005562 | Xenobiotic receptors | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| R01EY009339 | Retinoids in Vision | 5 | 2025 |
| R01HD010808 | Hormonal Regulation Sertoli Cell Maturation | 5 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 4 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 4 | 2025 |
| P30DK017047 | Diabetes Research Center | 4 | 2025 |
| ZIABC005708 | Xenobiotic metabolism, cancer chemoprevention and cancer biomarkers | 4 | 2025 |
| P30EY011373 | CWRU NEI Vision Center Core Grant | 3 | 2025 |
1 to 10 of 1,085Source NIH's project files
See all 1,085 nih grantsPapers1,665
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| An NR2F1-dependent retinoic acid network controls retinal specialization in mice and reveals foveal hypoplasia in patients with BBSOAS. | bioRxiv | 2026 | 42818154 | PubTator, text mining | PubMed |
| Human Organoids Reveal PTEN-Driven Mesendoderm Specification via Retinoic Acid Signaling Suppression. | Research (Wash D C) | 2026 | 42602118 | PubTator, text mining | PubMed |
| ATF3/SOX11-regulated FST activates IGF1R-ERK/AKT-Sp1 signaling to sustain trigeminal neuropathic pain. | Acta Pharmacol Sin | 2026 | 42477143 | PubTator, text mining | PubMed |
| Elevated ESR2 and BRCA1 gene expression in adenomyosis associated with endometrial cancer: a pilot study. | Gynecol Endocrinol | 2026 | 42329179 | PubTator, text mining | PubMed |
| Screening of cytochrome CYP26A1 expression in different bone tumors. | BMC Cancer | 2026 | 42316073 | PubTator, text mining | PubMed |
| Genome-wide analysis implicates inner ear development in Ménière disease. | Am J Hum Genet | 2026 | 42302782 | PubTator, text mining | PubMed |
| Retinoic acid regulates foveal development in the human retina. | Cell Rep | 2026 | 42213783 | PubTator, text mining | PubMed |
| Bilateral bifoveate retina in a human resembling lizard foveal architecture. | Ophthalmic Genet | 2026 | 42210632 | PubTator, text mining | PubMed |
| A Sertoli valve niche at the terminal end of seminiferous tubules for mammalian spermatogenic stem cells. | Curr Top Dev Biol | 2026 | 42097811 | PubTator, text mining | PubMed |
| New insights into the role of CYP26 in retinoic acid clearance. | Expert Opin Drug Metab Toxicol | 2026 | 42023600 | PubTator, text mining | PubMed |
1 to 10 of 1,665
See all 1,665 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1592
GET https://conductscience.org/api/genes/v1/1592/patents