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Gene · 1812

DRD1: dopamine receptor D1

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. DRD1: dopamine receptor D1. Genes, record 1812. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/1812

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
DRD1
HGNC
Name
dopamine receptor D1
HGNC
NCBI Gene ID
1812
NCBI Gene
HGNC ID
HGNC:3020
HGNC
Ensembl
ENSG00000184845
NCBI Gene
Aliases
D1R, DADR, DRD1A
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P21728Dopamine receptor D144631Ensembl, GeneID, HGNC

Source UniProt

Patents64

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026062654 A2026-04-1035P21728Espacenet
JP 2026004568 A2026-01-1444191P21728Espacenet
JP 2026004568 A2026-01-1444192P21728Espacenet
JP 2025529142 A2025-09-041318P21728Espacenet
US 12371689 B22025-07-291318P21728Espacenet
JP 2025081661 A2025-05-2719P21728Espacenet
JP 2025032204 A2025-03-1127508P21728Espacenet
EP 4461818 A22024-11-1327508P21728Espacenet
US 11860166 B22024-01-021P21728Espacenet
JP 2023156353 A2023-10-2435P21728Espacenet

1 to 10 of 64

See all 64 patents

Drugs16

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AMINEPTINECHEMBL418995Dopamine D1 and D2 receptor antagonistANTAGONISTChEMBL
AMOXAPINECHEMBL1113Dopamine receptor antagonistANTAGONISTChEMBL
ECOPIPAMCHEMBL298406Dopamine D1 receptor antagonistANTAGONISTChEMBL
ERGOLOIDCHEMBL2364968Dopamine receptor agonistAGONISTChEMBL
ERGOLOID MESYLATESCHEMBL2311030Dopamine receptor agonistAGONISTChEMBL
FENOLDOPAMCHEMBL588Dopamine D1 receptor agonistAGONISTChEMBL
FENOLDOPAM MESYLATECHEMBL1026Dopamine D1 receptor agonistAGONISTChEMBL
METHYLERGONOVINECHEMBL1201356Dopamine D1 receptor antagonistANTAGONISTChEMBL
METHYLERGONOVINE MALEATECHEMBL1200843Dopamine D1 receptor antagonistANTAGONISTChEMBL
MEVIDALENCHEMBL3421729Dopamine D1 receptor positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL

1 to 10 of 16

See all 16 drugs

Trials47

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06538116MEVIDALENPHASE2ClinicalTrials.gov
NCT05610189TAVAPADONPHASE1ClinicalTrials.gov
NCT05507372PIMOZIDEClinicalTrials.gov
NCT05030129ERGOLOID MESYLATESPHASE22024-09-19ClinicalTrials.gov
NCT04760769TAVAPADONPHASE3ClinicalTrials.gov
NCT04542499TAVAPADONPHASE32025-03-25ClinicalTrials.gov
NCT04529226PIMOZIDEPHASE2ClinicalTrials.gov
NCT04295642TAVAPADONPHASE1ClinicalTrials.gov
NCT04223193TAVAPADONPHASE32025-11-21ClinicalTrials.gov
NCT04201093TAVAPADONPHASE32025-07-28ClinicalTrials.gov

1 to 10 of 47

See all 47 trials

NIH grants3,209

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
ZIADA000493Functional and Pharmacological Significance of Receptor Heteromers in the CNS212025
ZIAAA000301Integrative genetics of behavior with high throughput technologies102025
ZIAAA000550Neurobiology of Drug Reward and Addiction102025
P50AA012870Center for the Translational Neuroscience of Alcoholism82025
R01DA012864Mechanisms and Cellular Function of Opioid Receptor Endocytosis82025
UL1TR001863Yale Clinical and Translational Science Award82025
U10AA008401Collaborative Study on the Genetics of Alcoholism (COGA).72025
ZIANS002263Molecular And Pharmacological Studies Of Dopamine Receptors62025
P51OD011132Emory National Primate Research Center52025
R01HL092961Epithelial-Mesenchymal Interactions in Fibrosis Resolution52025

1 to 10 of 3,209Source NIH's project files

See all 3,209 nih grants

Papers4,249

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818391PubTator, text miningPubMed
42817951PubTator, text miningPubMed
42747659PubTator, text miningPubMed
42740717PubTator, text miningPubMed
42711392PubTator, text miningPubMed
42650151PubTator, text miningPubMed
42624217PubTator, text miningPubMed
42599341PubTator, text miningPubMed
42576224PubTator, text miningPubMed
42567445PubTator, text miningPubMed

1 to 10 of 4,249

See all 4,249 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1812

GET https://conductscience.org/api/genes/v1/1812/patents?page=2