ConductScience.org, home

Gene · 1909

EDNRA: endothelin receptor type A

11 sourcesgene-search-2026-11-11-0.1.0

Download JSON
Cite this record

ConductScience Library. EDNRA: endothelin receptor type A. Genes, record 1909. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/1909

On this page

Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
EDNRA
HGNC
Name
endothelin receptor type A
HGNC
NCBI Gene ID
1909
NCBI Gene
HGNC ID
HGNC:3179
HGNC
Ensembl
ENSG00000151617
NCBI Gene
Aliases
ET-A, ETA, ETA-R, ETAR, ETRA, MFDA, hET-AR
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P25101Endothelin-1 receptor4275Ensembl, GeneID, HGNC

Source UniProt

Patents66

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026062654 A2026-04-1036P25101Espacenet
US 12594334 B22026-04-072P25101Espacenet
EP 4698223 A22026-02-2533P25101Espacenet
JP 2026004568 A2026-01-1444982P25101Espacenet
JP 2026000906 A2026-01-06218P25101Espacenet
EP 4650780 A22025-11-194987P25101Espacenet
EP 4641201 A22025-10-294571P25101Espacenet
JP 2025143267 A2025-10-012P25101Espacenet
JP 2025529142 A2025-09-041354P25101Espacenet
US 12371689 B22025-07-291354P25101Espacenet

1 to 10 of 66

See all 66 patents

Drugs17

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AMBRISENTANCHEMBL1111Endothelin receptor, ET-A/ET-B antagonistANTAGONISTChEMBL
APROCITENTANCHEMBL2165326Endothelin receptor, ET-A/ET-B antagonistANTAGONISTChEMBL
ATRASENTANCHEMBL9194Endothelin receptor ET-A antagonistANTAGONISTChEMBL
ATRASENTAN HYDROCHLORIDECHEMBL2106068Endothelin receptor ET-A antagonistANTAGONISTChEMBL
AVOSENTANCHEMBL3989834Endothelin receptor ET-A antagonistANTAGONISTChEMBL
BOSENTANCHEMBL957Endothelin receptor, ET-A/ET-B antagonistANTAGONISTChEMBL
BQ-123CHEMBL314691Endothelin receptor ET-A antagonistANTAGONISTChEMBL
CLAZOSENTANCHEMBL109648Endothelin receptor ET-A antagonistANTAGONISTChEMBL
DARUSENTANCHEMBL23261Endothelin receptor ET-A antagonistANTAGONISTChEMBL
ENRASENTANCHEMBL431651Endothelin receptor ET-A antagonistANTAGONISTChEMBL

1 to 10 of 17

See all 17 drugs

Trials258

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants2,715

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA016672Cancer Center Support Grant72025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal72025
I01BX000347Cerebral Arteriole Structure/Function in Diabetic Ischemic Brain Injury62025
ZIADK031117Development of Drugs Acting at Adenosine Receptors62025
IK6BX004471BLR&D Research Career Scientist Award Application52025
R01DK097253Glomerular Cell-Cell Crosstalk and Injury52025
UL1TR001881UCLA Clinical and Translational Science Institute52025
P30DK063491Diabetes Research Center (DRC)42025
P30ES013508Center of Excellence in Environmental Toxicology42025
R01HD072929Optimal Oxygenation in Neonatal Lung Injury42025

1 to 10 of 2,715Source NIH's project files

See all 2,715 nih grants

Papers4,314

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42819474PubTator, text miningPubMed
42805907PubTator, text miningPubMed
42788054PubTator, text miningPubMed
42783407PubTator, text miningPubMed
42753274PubTator, text miningPubMed
42710913PubTator, text miningPubMed
42653807PubTator, text miningPubMed
42548907PubTator, text miningPubMed
42496060PubTator, text miningPubMed
42449925PubTator, text miningPubMed

1 to 10 of 4,314

See all 4,314 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1909

GET https://conductscience.org/api/genes/v1/1909/patents?page=2