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Gene · 200576

Papers1,790

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Spatial transcriptomics uncovers lipid metabolic dysregulation driving immune-stroma crosstalk in Sjögren's Disease.EBioMedicine202641411773PubTator, text miningPubMed
Vesicle-coupled mRNA transport and translation govern intracellular organelle networking.EMBO Rep202641398320PubTator, text miningPubMed
PIKfyve inhibition in MM disrupts autophagy and lysosome function, increasing MHC expression and cholesterol metabolism.Blood202641191517PubTator, text miningPubMed
PIP5K3 upregulation correlates with unfavorable prognosis in patients with nasopharyngeal carcinoma.Histol Histopathol202641025721PubTator, text miningPubMed
PtdIns(3,5)P2 Is an Endogenous Ligand of STING in Innate Immune Signaling.bioRxiv202541550346PubTator, text miningPubMed
In silico discovery and experimental validation of natural derivatives as inhibitor of phosphoinositide Kinase, PIKfyve.J Comput Aided Mol Des202541460591PubTator, text miningPubMed
Lysosomal swelling triggers LRRK2 activity.bioRxiv202541427358PubTator, text miningPubMed
How endosomal PIKfyve inhibition prevents viral membrane fusion and entry.bioRxiv202541394603PubTator, text miningPubMed
LRRK2 integrates Rab and GABARAP interactions to sense and respond to distinct lysosomal stresses.bioRxiv202541332754PubTator, text miningPubMed
Quantitative comparison of PI(3,5)P2 biosensors reveals SnxA is the most sensitive and unbiased.bioRxiv202541332725PubTator, text miningPubMed
Disruption of the PIKfyve complex unveils an adaptive mechanism to promote lysosomal repair and mitochondrial homeostasis.Nat Commun202541315403PubTator, text miningPubMed
Tau seeding in neurons enabled by transient endolysosomal perforations are confined within endolysosomes.bioRxiv202541278722PubTator, text miningPubMed
Differential responses and adaptive mechanisms of diatoms and dinoflagellates to changes in dissolved organic nitrogen components.Harmful Algae202541241551PubTator, text miningPubMed
Enhanced Notch dependent gliogenesis and delayed physiological maturation underlie neurodevelopmental defects in Lowe syndrome.EMBO Mol Med202541219536PubTator, text miningPubMed
Extracellular vesicles: cargo loading, degradation and secretory pathways, and their intersection with autophagy.Extracell Vesicles Circ Nucl Acids202541132500PubTator, text miningPubMed
Structure-Activity Relationship Study of 3-Alkynyl-6-aryl-isothiazolo[4,3-b]pyridines as Dual Inhibitors of the Lipid Kinases PIKfyve and PIP4K2C.Pharmaceuticals (Basel)202541011211PubTator, text miningPubMed
Maintenance of neuronal TDP-43 expression requires axonal lysosome transport.Elife202540970386PubTator, text miningPubMed
Molecular requirements for mammalian crinophagy highlight a key role for Ca2+-dependent Munc13-4.Res Sq202540951263PubTator, text miningPubMed
SH2-mediated steric occlusion of the C2 domain regulates autoinhibition of SHIP1 inositol 5-phosphatase.bioRxiv202540949984PubTator, text miningPubMed
Amino acid-dependent TSC2 dephosphorylation by lysosome-PP2A regulates mTORC1 signaling transduction.Life Sci Alliance202540897470PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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