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Gene · 200576

Papers1,790

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Alpha-synuclein inclusions reduced by PIKfyve inhibition in Parkinson disease cell models.Neurobiol Dis202540812540PubTator, text miningPubMed
Identification of Anticancer Target Combinations to Treat Pancreatic Cancer and Its Associated Cachexia Using Constraint-Based Modeling.Molecules202540807373PubTator, text miningPubMed
PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2.Nat Commun202540640184PubTator, text miningPubMed
PIKfyve Inhibition Induces Antitumor Immunogenicity by Attenuating STING Trafficking and Lysosomal Degradation.Cancer Immunol Res202540403159PubTator, text miningPubMed
The role of autophagy in the pathogenesis and treatment of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).Autophagy Rep202540395983PubTator, text miningPubMed
PI3-kinase has multiple functions in asexual blood stages of Plasmodium falciparum.Sci Rep202540369090PubTator, text miningPubMed
CRISPRi screening identifies PIKfyve as a co-therapeutic target for obinutuzumab.Clin Transl Med202540342289PubTator, text miningPubMed
VAC14 oligomerization is essential for the function of the FAB1/PIKfyve-VAC14-FIG4 complex.Mol Biol Cell202540305106PubTator, text miningPubMed
Finding antibodies in cryo-EM maps with CrAI.Bioinformatics202540203077PubTator, text miningPubMed
The Use of PI-FAB Score in Evaluating mpMRI After Focal Ablation of Prostate Cancer: Is It Reliable? Inter-Reader Agreement in a Tertiary Care Referral University Hospital.Cancers (Basel)202540149364PubTator, text miningPubMed
Concurrent Inhibition of the RAS-MAPK Pathway and PIKfyve Is a Therapeutic Strategy for Pancreatic Cancer.Cancer Res202539932818PubTator, text miningPubMed
PIKFYVE deficiency induces vacuole-like cataract via perturbing late endosome homeostasis.Biochem Biophys Res Commun202539778216PubTator, text miningPubMed
Targeting Nav1.7 and Nav1.8 with a PIKfyve inhibitor to reverse inflammatory and neuropathic pain.Neurobiol Pain202539720155PubTator, text miningPubMed
Neuronal constitutive endolysosomal perforations enable α-synuclein aggregation by internalized PFFs.J Cell Biol202539714357PubTator, text miningPubMed
Genetic variants in PIKFYVE: A review of ocular phenotypes.Exp Eye Res202539694407PubTator, text miningPubMed
Structure-based virtual screening of FDA-approved drugs to discover potential inhibitors of phosphoinositide kinase, PIKfyve.J Biomol Struct Dyn202539660560PubTator, text miningPubMed
PIKFYVE inhibition induces endosome- and lysosome-derived vacuole enlargement via ammonium accumulation.J Cell Sci202539588583PubTator, text miningPubMed
[Analysis of PIKFYVE gene expression, clinical significance, and experimental validation based on TCGA database in hepatocellular carcinoma].Zhonghua Gan Zang Bing Za Zhi202539528312PubTator, text miningPubMed
PIP5K-Ras bistability triggers plasma membrane symmetry breaking to define cellular polarity and regulate migration.bioRxiv202539314378PubTator, text miningPubMed
PI(3,5)P 2 Controls the Signaling Activity of Class I PI3K.bioRxiv202536747849PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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