ConductScience.org, home

Gene · 2104

ESRRG: estrogen related receptor gamma

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. ESRRG: estrogen related receptor gamma. Genes, record 2104. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2104

On this page

Gene

Symbol
ESRRG
HGNC
Name
estrogen related receptor gamma
HGNC
NCBI Gene ID
2104
NCBI Gene
HGNC ID
HGNC:3474
HGNC
Ensembl
ENSG00000196482
NCBI Gene
Aliases
CONMAE, ERR-gamma, ERR3, ERRg, ERRgamma, NR3B3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P62508Estrogen-related receptor gamma45843Ensembl, GeneID, HGNC

Source UniProt

Patents60

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026076236 A2026-05-1147P62508Espacenet
JP 2026004568 A2026-01-1445305P62508Espacenet
EP 4641201 A22025-10-2912880P62508Espacenet
JP 2025147176 A2025-10-0614945P62508Espacenet
JP 2025517969 A2025-06-1212880P62508Espacenet
JP 2025032204 A2025-03-1127962P62508Espacenet
JP 2025028160 A2025-02-2814945P62508Espacenet
US 12213999 B22025-02-041P62508Espacenet
KR 1020250010750 A2025-01-2114945P62508Espacenet
US 12168778 B22024-12-1747P62508Espacenet

1 to 10 of 60

See all 60 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
AFIMOXIFENECHEMBL489Estrogen-related receptor gamma antagonistANTAGONIST

Source ChEMBL

Trials2

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT04009044AFIMOXIFENEPHASE2ClinicalTrials.gov
NCT02993159AFIMOXIFENEPHASE22024-12-18ClinicalTrials.gov

NIH grants1,380

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleESRRG papersNewest fiscal year
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant112025
P30CA014195Cancer Center Support Grant (CCSG)82025
T32CA009686Training Grant In Tumor Biology82025
P30DK063491Diabetes Research Center (DRC)72025
P30ES017885Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD)72025
P30DK019525University of Pennsylvania Diabetes Research Center52025
P30DK056341Washington University Nutrition Obesity Research Center52025
P30CA068485Cancer Center Support Grant42025
R01AI045050Characterization of SLE-susceptibility loci on mouse chromosome 142025
R01HL057181Cardiogenesis: Molecular Mechanisms42025

1 to 10 of 1,380Source NIH's project files

See all 1,380 nih grants

Papers1,736

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Convolvulus althaeoides as a Potential Natural Source in Cancer Prophylaxis and Treatment: LC-ESI-MS/MS, GC-MS, In Vitro, and In Silico Investigations.Chem Biodivers202642814524PubTator, text miningPubMed
Histone demethylase KDM4A promotes endometrial cancer progression through an ERRγ-associated cell-cycle regulatory axis.Int J Biol Sci202642807380PubTator, text miningPubMed
Stable simulations do not guarantee functional engagement: a case study of off-target prediction for Seladelpar and Zanamivir.J Comput Aided Mol Des202642690469PubTator, text miningPubMed
Screening of core targets for Di(2-ethylhexyl) Phthalate-related gastric cancer based on machine learning, molecular docking, and SHAP analysis.PLoS Comput Biol202642461936PubTator, text miningPubMed
Estrogen-related receptor γ functions as a novel corepressor of androgen receptor by destabilizing receptor conformation and blocking coactivator recruitment.J Biochem202642383774PubTator, text miningPubMed
Identification and Prognostic Analysis of Immune-Related Genes Co-Regulated by Key Histone Modifications in Breast Cancer.Curr Issues Mol Biol202642353587PubTator, text miningPubMed
Pharmacology of estrogen-related receptors (ERRs) agonists.RSC Chem Biol202642256350PubTator, text miningPubMed
Multimechanistic actions of functional factors in enhancing physical strength and endurance: a scoping review of nutritional basis and natural extracts.Front Sports Act Living202642211549PubTator, text miningPubMed
Reduced HSD17B1 expression in preeclampsia: integrated transcriptomic, summary Mendelian randomization, immune deconvolution, and experimental validation.BMC Pregnancy Childbirth202642210128PubTator, text miningPubMed
Scale-Up Isolation of High-Purity Shatavarins from Asparagus racemosus via Flash Chromatography with Bioavailability and Pharmacological Insights.ACS Omega202641970898PubTator, text miningPubMed

1 to 10 of 1,736

See all 1,736 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2104

GET https://conductscience.org/api/genes/v1/2104/patents?page=2