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ACSL4: acyl-CoA synthetase long chain family member 4
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Gene · 2182

Papers4,043

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

481 to 500 of 4,043

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TitleJournalYearPMIDFound bySource
Ginsenoside Re attenuates homocysteine-induced endothelial cell ferroptosis through upregulation of GPX4/xCT signaling.Exp Ther Med202641356750PubTator, text miningPubMed
EMP1-driven ferroptosis in liver sinusoidal endothelial cells exacerbates hepatic ischemia-reperfusion injury via P38 MAPK.Free Radic Biol Med202641352380PubTator, text miningPubMed
PRDX1 depletion predisposes to ferroptosis through inhibiting the cAMP pathway in B-cell acute lymphoblastic leukemia.Cancer Gene Ther202641350460PubTator, text miningPubMed
RBM15-mediated m6A modification upregulates KDM2A to promote ferroptosis in osteoarthritis cells.Tissue Cell202641349348PubTator, text miningPubMed
Ochratoxin A induces intestinal barrier impairment and concurrent hepatorenal toxicity in broiler chicks via modulation of autophagy, ferroptosis, and the intestinal microbiota.Res Vet Sci202641349214PubTator, text miningPubMed
Harmine inhibits non-small cell lung cancer growth by targeting phosphodiesterase4D and inducing ferroptosis.Phytomedicine202641344272PubTator, text miningPubMed
α-Hederin inhibits osteosarcoma progression by triggering ferroptosis and disrupting mitochondrial function via PI3K/AKT signalling.Xenobiotica202641342440PubTator, text miningPubMed
Oxidative stress as a nexus: Integrating mitophagy and ferroptosis in endometrial carcinogenesis (Review).Oncol Lett202641340874PubTator, text miningPubMed
Ferroptosis modulates invasion and migration in prostate cancer PC-3M subclones.Exp Cell Res202641325788PubTator, text miningPubMed
S-palmitoylation of MTDH regulates ferroptosis resistance in breast cancer cell.J Lipid Res202641318030PubTator, text miningPubMed
N6-methyladenosine (m6A) modification regulates LONP1 to inhibit coxsackievirus B3 replication by suppressing virus-induced ferroptosis.Int J Biol Macromol202641317762PubTator, text miningPubMed
Molecular code of ferroptosis: emerging multi-dimensional modifications and therapeutic targets in hepatic disorders.Metabolism202641314379PubTator, text miningPubMed
METTL14 Inhibits Human Lung Microvascular Endothelial Cell From Ferroptosis in Septic Lung Injury by Regulating N6-Methyladenosine-Modified ACSL4 Level.Clin Exp Pharmacol Physiol202641312681PubTator, text miningPubMed
Epigenetic regulation of ACSL4 via H2A monoubiquitylation connects lipid metabolism to BAP1-mediated ferroptosis.Cell Death Differ202641310183PubTator, text miningPubMed
Sagittaria sagittifolia polysaccharide regulates Nrf2-mediated antioxidant to improve apoptosis and ferroptosis in high glucose-induced lens epithelial cells.Exp Cell Res202641297623PubTator, text miningPubMed
Cell size modulates ferroptosis susceptibility.bioRxiv202641279670PubTator, text miningPubMed
Ferroptosis in Tubular Epithelial Cells Across Distinct Renal Regions Is a Primary Causal Factor for Lupus Nephritis.Antioxid Redox Signal202641271211PubTator, text miningPubMed
Acetylation Regulates ACSL4 Degradation Through Chaperone-Mediated Autophagy to Alleviate Intervertebral Disc Degeneration.Adv Sci (Weinh)202641270209PubTator, text miningPubMed
Biomarkers of endothelial damage in erectile dysfunction based on preclinical studies: a systematic review.Int Urol Nephrol202641269480PubTator, text miningPubMed
USP54 Promotes Ferroptosis in Non-Small Cell Lung Cancer by Mediating FOXA2 Deubiquitination and Enhancing ACSL4 Transcription.Kaohsiung J Med Sci202641267551PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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