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ACSL4: acyl-CoA synthetase long chain family member 4
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Gene · 2182

Papers4,043

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

501 to 520 of 4,043

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TitleJournalYearPMIDFound bySource
Long photoperiod induces porphyrin accumulation while maintaining lipid peroxidation stability in Harderian glands of female striped dwarf hamsters.Biochimie202641260563PubTator, text miningPubMed
ACSL4 coordinates metabolic and cell cycle reprogramming to promote endometrial cancer progression.Cell Signal202641260237PubTator, text miningPubMed
L-theanine alleviates muscle oxidative damage by improving mitochondrial function, maintaining calcium homeostasis, and inhibiting ferroptosis.J Nutr Biochem202641237995PubTator, text miningPubMed
SCARA5 Induces Ferroptosis to Inhibit the Proliferation and Migration of Skin Melanoma Cells and Regulates the GPX4/ACSL4 Signaling Pathway.Arch Immunol Ther Exp (Warsz)202641206901PubTator, text miningPubMed
Ferroptosis modulation by METTL14 in cancers: From molecular insights to therapeutic strategies.Cell Signal202641203185PubTator, text miningPubMed
ESR1-Activating Mutations Confer Metabolic Vulnerabilities in ER+ Breast Cancer.Cancer Res202641201246PubTator, text miningPubMed
Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway.Mol Med Rep202641201015PubTator, text miningPubMed
Role of persistent necroinflammation in chronic tissue remodeling and organ fibrosis.Am J Physiol Cell Physiol202641171080PubTator, text miningPubMed
Lactate/AARS1/H3K18la/LDHA positive feedback loop triggers ferroptosis, which participates in diabetic nephropathy via the modulation of ACSL4 transcription.Acta Biochim Biophys Sin (Shanghai)202641169201PubTator, text miningPubMed
Silencing of SOX4 prevents endothelial injury from ox-LDL stimulation by inhibiting NF-κB pathway and ferroptosis.Tissue Cell202641166996PubTator, text miningPubMed
Cadmium induces ferroptosis in B cells via ATP6V0A1-upregulated lysosomal ferritinophagy: insights from murine transcriptomics and human cellular models.Free Radic Biol Med202641161393PubTator, text miningPubMed
Apoptotic extracellular vesicles derived from UC-MSCs promote spinal cord injury repair by inhibiting ferroptosis via OTUD1.Free Radic Biol Med202641151199PubTator, text miningPubMed
ZDHHC2-Dependent Palmitoylation Dictates Ferroptosis and Castration Sensitivity in Prostate Cancer via Controlling ACSL4 Degradation and Lipid Peroxidation.Adv Sci (Weinh)202641126755PubTator, text miningPubMed
CIITA was involved in regulating ACSL4-dependent ferroptosis in gastric cancer cells.Mol Cell Biochem202641114762PubTator, text miningPubMed
Androgen receptors protect against thoracic aortic dissection via inhibiting ferroptosis of vascular smooth muscle cells in male patients.Chin Med J (Engl)202641098143PubTator, text miningPubMed
Nitrosative Stress, Mitochondrial Peptides, and Ferroptosis Markers in Corneal Epithelial Cells from Keratoconus Patients.Curr Eye Res202641088780PubTator, text miningPubMed
MC1R contributes to ferroptosis resistance and tumor aggressiveness in colorectal cancer by activating Notch signaling.Cancer Gene Ther202641087754PubTator, text miningPubMed
ACSL4-Mediated Ferroptosis and its Biological Functions and Potential Therapeutic Significance in Liver Diseases.Curr Pharm Des202641084260PubTator, text miningPubMed
Integrated proteomic and metabolomic analysis reveals lipid metabolic dysregulation and ferroptosis as potential drivers of placental dysfunction in intrahepatic cholestasis of pregnancy.Biochim Biophys Acta Mol Cell Biol Lipids202641047095PubTator, text miningPubMed
Inflammation-targeted nanoplatform: NIR-II imaging-guided encephalitis suppressing by dual antioxidant-ferroptosis action.Biomaterials202641016349PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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