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Gene · 2696

GIPR: gastric inhibitory polypeptide receptor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GIPR: gastric inhibitory polypeptide receptor. Genes, record 2696. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2696

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Gene

Symbol
GIPR
HGNC
Name
gastric inhibitory polypeptide receptor
HGNC
NCBI Gene ID
2696
NCBI Gene
HGNC ID
HGNC:4271
HGNC
Ensembl
ENSG00000010310
NCBI Gene
Aliases
PGQTL2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P48546Gastric inhibitory polypeptide receptor46613Ensembl, GeneID, HGNC

Source UniProt

Patents132

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4777830 A12026-07-2210P48546Espacenet
JP 2026518415 A2026-06-081P48546Espacenet
EP 4750795 A12026-06-03220P48546Espacenet
JP 2026048788 A2026-03-173141P48546Espacenet
JP 2026004568 A2026-01-1447386P48546Espacenet
JP 2026004568 A2026-01-1447388P48546Espacenet
KR 1020250175337 A2025-12-161P48546Espacenet
EP 4650780 A22025-11-1917754P48546Espacenet
EP 4640849 A22025-10-293508P48546Espacenet
EP 4641201 A22025-10-2921958P48546Espacenet

1 to 10 of 132

See all 132 patents

Drugs2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
RETATRUTIDECHEMBL5095485Gastric inhibitory polypeptide receptor agonistAGONISTChEMBL
TIRZEPATIDECHEMBL4297839Gastric inhibitory polypeptide receptor agonistAGONISTChEMBL

Trials176

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

1 to 10 of 176

See all 176 trials

NIH grants1,100

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGIPR papersNewest fiscal year
P30DK020572Michigan Diabetes Research Center (MDRC)122025
P30DK063491Diabetes Research Center (DRC)92025
R01DK062370Identifying Genes for Type 2 Diabetes: FUSION92025
R01DK093757Genetic epidemiology of rare and regulatory variants for metabolic traits82025
P30DK020595Diabetes Research and Training Center72025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal72025
ZIAHG000024Genetic analysis of type II diabetes72025
R01DK075787Biological Insights from Genetic Investigation of ANthropometric Traits (GIANT) Across the Allelic Spectrum62025
P30DK017047Diabetes Research Center52025
T32HL007055Cardiovascular Epidemiology Training Grant52025

1 to 10 of 1,100Source NIH's project files

See all 1,100 nih grants

Papers1,380

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Genetically Proxied GIP-GIPR Pathway Perturbation and Fracture Risk.Diabetes Obes Metab202642811415PubTator, text miningPubMed
Skeletal Muscle Effects of GLP 1 Receptor Agonists: Molecular Mechanisms and Comparative Insights on Semaglutide and Tirzepatide, a Narrative Review.Int J Mol Sci202642794486PubTator, text miningPubMed
Genetic Assessment of Oesophageal Safety of GLP-1 and GIP Receptor Perturbation: A Drug-Target Mendelian Randomisation Study.Biomedicines202642792631PubTator, text miningPubMed
Genome-wide mapping of common and rare variant effects on adiposity across childhood.Nat Genet202642791368PubTator, text miningPubMed
Pulsatile liraglutide on a biased tirzepatide background: a hypothesis.Front Endocrinol (Lausanne)202642787169PubTator, text miningPubMed
GLP-1 receptor agonists and podocyte senescence in diabetic kidney disease: structural pharmacology, mechanistic evidence, and multi-receptor agonism.Biochem Pharmacol202642777788PubTator, text miningPubMed
AGA Clinical Practice Update on the Evaluation and Management of Metabolic Dysfunction- and Alcohol-Associated Liver Disease: Expert Review.Clin Gastroenterol Hepatol202642776095PubTator, text miningPubMed
The incretin-joint axis: weight-independent mechanisms and disease-modifying potential in chronic arthropathies.Rheumatol Adv Pract202642774139PubTator, text miningPubMed
Effectiveness, Safety and Pharmacokinetics of BGM0504, a Dual GLP-1/GIP Receptor Agonist, in Chinese Adults With Overweight or Obesity Without Diabetes: A Phase 2 Multicentre, Randomized, Double-Blind, Placebo-Controlled Trial.
Diabetes Obes Metab202642755112PubTator, text miningPubMed
Redefining weight management after liver transplantation with glucagon-like peptide one and gastric inhibitory polypeptide receptor agonists.World J Transplant202642751234PubTator, text miningPubMed

1 to 10 of 1,380

See all 1,380 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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