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Gene · 27035

NOX1: NADPH oxidase 1

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. NOX1: NADPH oxidase 1. Genes, record 27035. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/27035

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
NOX1
HGNC
Name
NADPH oxidase 1
HGNC
NCBI Gene ID
27035
NCBI Gene
HGNC ID
HGNC:7889
HGNC
Ensembl
ENSG00000007952
NCBI Gene
Aliases
GP91-2, MOX1, NOH-1, NOH-1L, NOH1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9Y5S8NADPH oxidase 15640Ensembl, GeneID, HGNC

Source UniProt

Patents45

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1455005Q9Y5S8Espacenet
JP 2025529142 A2025-09-042866Q9Y5S8Espacenet
US 12371689 B22025-07-292866Q9Y5S8Espacenet
JP 2024156868 A2024-11-062Q9Y5S8Espacenet
US 11446398 B22022-09-2055287Q9Y5S8Espacenet
US 11400116 B22022-08-023623Q9Y5S8Espacenet
JP 2022524081 A2022-04-27158258Q9Y5S8Espacenet
US 11041209 B22021-06-22981Q9Y5S8Espacenet
US 10857244 B22020-12-08112Q9Y5S8Espacenet
WO 2020153467 A2020-07-307Q9Y5S8Espacenet

1 to 10 of 45

See all 45 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
SETANAXIBCHEMBL4303187NADPH oxidase 1 inhibitorINHIBITOR

Source ChEMBL

Trials6

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06274489SETANAXIBPHASE1/PHASE2ClinicalTrials.gov
NCT05323656SETANAXIBPHASE22025-05-09ClinicalTrials.gov
NCT05014672SETANAXIBPHASE22025-04-24ClinicalTrials.gov
NCT03865927SETANAXIBPHASE2ClinicalTrials.gov
NCT03226067SETANAXIBPHASE22022-03-31ClinicalTrials.gov
NCT02010242SETANAXIBPHASE22025-02-28ClinicalTrials.gov

NIH grants2,115

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
ZIABC010677NADPH Oxidases as Novel Targets for Cancer Therapy162025
P30DK054759Precision Medicine Center for Cystic Fibrosis122025
P30CA118100University of New Mexico Cancer Center Support Grant82025
P50AA011999Southern California Research Center for ALPD and Cirrhosis72025
P30CA016672Cancer Center Support Grant52025
P30ES005605Environmental Health Sciences Research Center52025
R01EY015130Mechanisms of Angiogenesis in ROP52025
R01EY017011Endothelial Transmigration in Neovascular Age-related Macular Degeneration52025
R01HL125926Galectin-3: A mediator of vascular remodeling in pulmonary arterial hypertension52025
U01DK062422Mount Sinai NYC Genetics Research Center: Multi-omic integration across data-types, cell niches and populations52025

1 to 10 of 2,115Source NIH's project files

See all 2,115 nih grants

Papers4,580

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42794457PubTator, text miningPubMed
42785059PubTator, text miningPubMed
42753829PubTator, text miningPubMed
42695285PubTator, text miningPubMed
42621875PubTator, text miningPubMed
42607534PubTator, text miningPubMed
42600360PubTator, text miningPubMed
42587812PubTator, text miningPubMed
42523594PubTator, text miningPubMed
42522403PubTator, text miningPubMed

1 to 10 of 4,580

See all 4,580 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/27035

GET https://conductscience.org/api/genes/v1/27035/patents?page=2