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HSD3B1: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
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Gene · 3283

Papers3,575

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

21 to 40 of 3,575

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TitleJournalYearPMIDFound bySource
Indications that the direct effects of supplemented vitamin D3 on the adrenal cortex are of secondary importance for glucocorticoid output.Horm Mol Biol Clin Investig202642190100PubTator, text miningPubMed
VISFATIN: a novel modulator of placental endocrinology under physiological and pathological conditions-in vitro studies involving INSR, ERK1/2, and PKA signalling pathways.Sci Rep202642178336PubTator, text miningPubMed
Dual-targeting phytochemicals Ergosterol and Quercetagetin implicate steroid metabolism-associated pathways in lung and liver cancer models.Front Pharmacol202642147323PubTator, text miningPubMed
FSH mediated endocrine disruption potential of Dibutyl phthalate in cultured ovine ovarian granulosa cells: Cytotoxicity, oxidative stress, steroidogenesis, cell senescence, and expression of related key developmental genes.
Reprod Toxicol202642119666PubTator, text miningPubMed
Nano-selenium attenuates cadmium-induced ER-phagy through inhibition of TFEB nuclear translocation and FAM134B downregulation.Free Radic Biol Med202642107477PubTator, text miningPubMed
Silica nanoparticles suppress porcine oocyte maturation via oxidative stress, metabolic dysfunction, and impaired cholesterol trafficking.Theriogenology202642105621PubTator, text miningPubMed
Integrative analysis of the hypothalamic-pituitary-testicular axis reveals molecular mechanisms underlying sperm motility differences in Landes ganders.Front Vet Sci202642100217PubTator, text miningPubMed
Lipophilicity and alkyl chain length govern pyridine quaternary ammonium disinfectants as gonadal 3β-hydroxysteroid dehydrogenase inhibitors: Implications for endocrine disruption.Chem Biol Interact202642082015PubTator, text miningPubMed
Environmentally relevant concentrations of nanoplastic increase the accumulation and endocrine effects of BDE47 and its metabolite 6-OH-BDE-47 in male frogs' testes.J Environ Sci (China)202642070867PubTator, text miningPubMed
Swainsonine induces granulosa cell apoptosis and steroidogenic impairment associated with oxidative stress and mitochondrial dysfunction.Anim Reprod Sci202641990565PubTator, text miningPubMed
Dynamic regulation of porcine luteal physiology by fibroblast growth factors: expression patterns and FGF2 modulation in-vitro.Vet Res Commun202641954841PubTator, text miningPubMed
Associations of Obesity, Inflammatory Indicators, and Serum Testosterone in Adult Males: A Cross-Sectional Study Based on NHANES 2011-2016 and 2021-2023.Am J Mens Health202641928545PubTator, text miningPubMed
Reproductive toxicity mechanisms of PNMC: Evidence from mitochondrial dysfunction and hormone synthesis disruption in the KGN cells.Reprod Toxicol202641856258PubTator, text miningPubMed
Natural astaxanthin enhances testosterone synthesis by improving mitochondrial function and reducing oxidative stress in Leydig cells.Poult Sci202641833117PubTator, text miningPubMed
Hydrophobicity, 3D complexity, and steric feature affect salicylate inhibition of human and rat gonadal 3β-hydroxysteroid dehydrogenases: Insights from experiments to 3D-QSAR and in silico docking analysis.
Chem Biol Interact202641812755PubTator, text miningPubMed
Environmental and microbiome determinants of sperm quality: a narrative review on male health.Transl Androl Urol202641809810PubTator, text miningPubMed
Live Births Following IVF-FET in Two Adult Sisters with Nonclassic P450 Oxidoreductase Deficiency: A Case Report Identifying a Novel POR Variant.Int J Womens Health202641809679PubTator, text miningPubMed
Inhibitory effects and molecular mechanisms of Aristolochic acids on human and rat placental 3β-hydroxysteroid dehydrogenases.J Ethnopharmacol202641791623PubTator, text miningPubMed
Exploring treatment models for oligometastatic castration-sensitive prostate cancer: evolution of therapeutic strategies.Front Oncol202641768233PubTator, text miningPubMed
Current insights into monitoring of congenital adrenal hyperplasia.Front Endocrinol (Lausanne)202641767372PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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