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Gene · 3446

IFNA10: interferon alpha 10

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. IFNA10: interferon alpha 10. Genes, record 3446. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3446

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Gene

Symbol
IFNA10
HGNC
Name
interferon alpha 10
HGNC
NCBI Gene ID
3446
NCBI Gene
HGNC ID
HGNC:5418
HGNC
Ensembl
ENSG00000186803
NCBI Gene
Aliases
IFN-alphaC
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P01566Interferon alpha-101890Ensembl, GeneID, HGNC

Source UniProt

Patents96

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026164090 A2026-08-063P01566Espacenet
EP 4724500 A22026-04-15424P01566Espacenet
EP 4705273 A22026-03-11537P01566Espacenet
EP 4650780 A22025-11-1910284P01566Espacenet
JP 2025169942 A2025-11-141091P01566Espacenet
JP 2025147176 A2025-10-066726P01566Espacenet
JP 2025529142 A2025-09-046647P01566Espacenet
US 12371689 B22025-07-296647P01566Espacenet
JP 2025517970 A2025-06-1210284P01566Espacenet
JP 2025028160 A2025-02-286726P01566Espacenet

1 to 10 of 96

See all 96 patents

Drugs2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
RONTALIZUMABCHEMBL1743066Interferon alpha inhibitorINHIBITORChEMBL
SIFALIMUMABCHEMBL1743069Interferon alpha inhibitorINHIBITORChEMBL

Trials10

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT01283139SIFALIMUMABPHASE22016-07-11ClinicalTrials.gov
NCT01031836SIFALIMUMABPHASE22018-11-19ClinicalTrials.gov
NCT00979654SIFALIMUMABPHASE22016-08-23ClinicalTrials.gov
NCT00962832RONTALIZUMABPHASE2ClinicalTrials.gov
NCT00657189SIFALIMUMABPHASE2ClinicalTrials.gov
NCT00541749RONTALIZUMABPHASE1ClinicalTrials.gov
NCT00533091SIFALIMUMABPHASE1ClinicalTrials.gov
NCT00482989SIFALIMUMABPHASE1ClinicalTrials.gov
NCT00472758SIFALIMUMABPHASE1ClinicalTrials.gov
NCT00299819SIFALIMUMABPHASE1ClinicalTrials.gov

NIH grants317

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleIFNA10 papersNewest fiscal year
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success52025
P30CA008748Cancer Center Support Grant32025
R01AI163029Inborn errors of immunity in patients with life-threatening COVID-1932025
R01AR071384Characterization of interferon kappa as a novel target in cutaneous lupus32025
P30CA016672Cancer Center Support Grant22025
P51OD011132Emory National Primate Research Center22025
R01AI130025Role of the gender biased transcription factor VGLL3 in promoting autoimmune responses in SLE22025
U19AI057229Understanding Influenza and SARS-CoV-2 vaccine responses, in vivo and in vitro22025
ZIAAI000887Role of HIV Envelope Proteins In Viral Replication and HIV Pathogenesis22025
I01CX002422Investigate the mechanism of autoreactive B cell-mediated immunological failure despite virologic suppression in HIV-infected individuals on antiretroviral therapy12025

1 to 10 of 317Source NIH's project files

See all 317 nih grants

Papers297

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Ferroptosis in Glioblastoma and Neuroblastoma: Molecular Mechanisms and Novel Therapeutic Strategies.Curr Issues Mol Biol202641899419PubTator, text miningPubMed
Essential role of hsa-miR-203a-3p in type I interferons immune homeostasis during influenza and NDV infection.RNA Biol202641784292PubTator, text miningPubMed
Fetal and Neonatal Immune Response to Congenital Cytomegalovirus (cCMV) Infection: A Systematically Conducted Scoping Review.Viruses202641754585PubTator, text miningPubMed
Elevated ferritin as a companion biomarker of myeloid-driven inflammation in RNP/Sm co-positive, treatment-resistant SLE endotype.bioRxiv202641727036PubTator, text miningPubMed
Somatic deficiency of the human E3 ubiquitin ligase CBL in leukocytes impairs B cell but not T cell development and function.Nat Immunol202641540267PubTator, text miningPubMed
Genetic Variants Specific to Critical COVID-19: Insights From Genome-Wide Association Studies and Structural Analysis.J Med Virol202541268733PubTator, text miningPubMed
Multimodal characterization of the responsiveness of eight hepatitis D virus genotype isolates to interferon-alpha treatment.J Virol202540965142PubTator, text miningPubMed
Rare genetic variants and severe COVID-19 in previously healthy admixed Latin American adults.Sci Rep202540595275PubTator, text miningPubMed
Rare Genetic Variants of NLRP12 in Admixed Latino-American Children With SARS-CoV-2-Related Multisystem Inflammatory Syndrome.J Infect Dis202439328079PubTator, text miningPubMed
Inhibition of SARS-CoV-2 infection and replication by Petasites hybridus CO2-extract (Ze 339).Biomed Pharmacother202438061134PubTator, text miningPubMed

1 to 10 of 297

See all 297 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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