Gene · 3588
IL10RB: interleukin 10 receptor subunit beta
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. IL10RB: interleukin 10 receptor subunit beta. Genes, record 3588. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3588
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q08334 | Interleukin-10 receptor subunit beta | 325 | 5 | Ensembl, GeneID, HGNC |
Source UniProt
Patents101
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026086659 A | 2026-05-26 | 166 | Q08334 | Espacenet |
| EP 4705273 A2 | 2026-03-11 | 305 | Q08334 | Espacenet |
| WO 2026019692 A2 | 2026-01-22 | 5 | Q08334 | Espacenet |
| US 12528850 B2 | 2026-01-20 | 53 | Q08334 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3416 | Q08334 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 2996 | Q08334 | Espacenet |
| JP 2025160224 A | 2025-10-22 | 53 | Q08334 | Espacenet |
| JP 2025134781 A | 2025-09-17 | 456 | Q08334 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2067 | Q08334 | Espacenet |
| JP 2025525778 A | 2025-08-07 | 5 | Q08334 | Espacenet |
1 to 10 of 101
See all 101 patentsDrugs3
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials30
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT05953545 | PEGINTERFERON LAMBDA-1A | PHASE2 | ClinicalTrials.gov | |
| NCT05205668 | EFLEPEDOCOKIN ALFA | PHASE2 | ClinicalTrials.gov | |
| NCT04967430 | PEGINTERFERON LAMBDA-1A | PHASE3 | ClinicalTrials.gov | |
| NCT04534673 | PEGINTERFERON LAMBDA-1A | PHASE2 | ClinicalTrials.gov | |
| NCT04498377 | EFLEPEDOCOKIN ALFA | PHASE2 | 2023-12-21 | ClinicalTrials.gov |
| NCT04388709 | PEGINTERFERON LAMBDA-1A | PHASE2 | ClinicalTrials.gov | |
| NCT04354259 | PEGINTERFERON LAMBDA-1A | PHASE2 | ClinicalTrials.gov | |
| NCT04344600 | PEGINTERFERON LAMBDA-1A | PHASE2 | 2022-07-14 | ClinicalTrials.gov |
| NCT04343976 | PEGINTERFERON LAMBDA-1A | PHASE2 | 2022-07-21 | ClinicalTrials.gov |
| NCT04331899 | PEGINTERFERON LAMBDA-1A | PHASE2 | 2021-04-22 | ClinicalTrials.gov |
1 to 10 of 30
See all 30 trialsNIH grants1,732
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | IL10RB papers | Newest fiscal year |
|---|---|---|---|
| UL1TR001866 | Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success | 22 | 2025 |
| P30DK034854 | Integrated Epithelial and Muscosal Biology | 17 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 9 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 8 | 2025 |
| R01AI163029 | Inborn errors of immunity in patients with life-threatening COVID-19 | 8 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| R01AI127564 | Genome-wide search for inborn errors of IL-17 immunity underlying chronic mucocutaneous candidiasis | 7 | 2025 |
| RC2DK118640 | COngenital Diarrhea and Enteropathy (PediCODE) Consortium and BioRepository | 6 | 2025 |
| P01CA018029 | Adult Leukemia Research Center | 5 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 5 | 2025 |
1 to 10 of 1,732Source NIH's project files
See all 1,732 nih grantsPapers2,588
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Identification of genetic variants associated with monogenic autoinflammatory diseases in patients with Still's disease using next-generation sequencing. | Immunol Res | 2026 | 42821198 | PubTator, text mining | PubMed |
| Interferon-λ receptor positive monocytes/macrophages orchestrate a pro-fibrotic immune environment in hepatitis B virus-related liver fibrosis. | Clin Sci (Lond) | 2026 | 42742113 | PubTator, text mining | PubMed |
| Connecting Skin and Gut in Dermatitis Herpetiformis: Insights from Gluten Challenge Transcriptomics. | Acta Derm Venereol | 2026 | 42713962 | PubTator, text mining | PubMed |
| Gut microbiota-derived metabolites and IL-22 signaling in inflammatory bowel disease: context-dependent regulation of mucosal repair and inflammation. | Front Immunol | 2026 | 42713082 | PubTator, text mining | PubMed |
| Genetic and autoimmune predispositions to fulminant viral hepatitis in children. | Front Immunol | 2026 | 42630887 | PubTator, text mining | PubMed |
| Single-cell and spatial profiling reveal an IL-10-associated iCAF-M2 macrophage communication axis in high-grade serous ovarian cancer ascites. | Front Immunol | 2026 | 42500684 | PubTator, text mining | PubMed |
| Systemic inflammatory networks in HIV-associated chronic obstructive pulmonary disease. | J Infect | 2026 | 42456981 | PubTator, text mining | PubMed |
| Serum Proteomic Profiles of Microvascular Inflammation in Donor-specific Antibody-negative and C4d-negative in Kidney Transplantation. | Transplantation | 2026 | 42441560 | PubTator, text mining | PubMed |
| Genotype-phenotype correlations in autoimmune and autoinflammatory diseases: An NGS-based immunogenetic cohort study. | Immunogenetics | 2026 | 42406132 | PubTator, text mining | PubMed |
| A preliminary analysis of the inflammatory protein landscape in the CSF of mid- to late-stage Parkinson's disease: associations with motor severity and subtypes. | BMC Neurol | 2026 | 42387333 | PubTator, text mining | PubMed |
1 to 10 of 2,588
See all 2,588 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3588
GET https://conductscience.org/api/genes/v1/3588/patents?page=2