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Gene · 3624

INHBA: inhibin subunit beta A

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. INHBA: inhibin subunit beta A. Genes, record 3624. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3624

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Gene

Symbol
INHBA
HGNC
Name
inhibin subunit beta A
HGNC
NCBI Gene ID
3624
NCBI Gene
HGNC ID
HGNC:6066
HGNC
Ensembl
ENSG00000122641
NCBI Gene
Aliases
EDF, FRP
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P08476Inhibin beta A chain42616Ensembl, GeneID, HGNC

Source UniProt

Patents294

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 12637661 B22026-05-263P08476Espacenet
US 12637661 B22026-05-266P08476Espacenet
US 12630608 B22026-05-1934P08476Espacenet
JP 2026062645 A2026-04-10286P08476Espacenet
EP 4705273 A22026-03-11185P08476Espacenet
EP 4698654 A12026-02-2527P08476Espacenet
JP 2026503880 A2026-02-0219P08476Espacenet
JP 2026503880 A2026-02-0222P08476Espacenet
JP 2026004568 A2026-01-1449746P08476Espacenet
JP 2026004568 A2026-01-1449747P08476Espacenet

1 to 10 of 294

See all 294 patents

Drugs2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
GARETOSMABCHEMBL4298176Inhibin beta A chain inhibitorINHIBITORChEMBL
SOTATERCEPTCHEMBL1743073Inhibin beta A chain inhibitorINHIBITORChEMBL

Trials39

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07600723SOTATERCEPTPHASE4ClinicalTrials.gov
NCT07559513GARETOSMABPHASE3ClinicalTrials.gov
NCT07498803SOTATERCEPTPHASE2ClinicalTrials.gov
NCT07356778SOTATERCEPTPHASE4ClinicalTrials.gov
NCT07301450GARETOSMABClinicalTrials.gov
NCT07266519SOTATERCEPTPHASE2ClinicalTrials.gov
NCT07218029SOTATERCEPTPHASE3ClinicalTrials.gov
NCT07140484SOTATERCEPTPHASE4ClinicalTrials.gov
NCT06925750SOTATERCEPTPHASE2ClinicalTrials.gov
NCT06814145SOTATERCEPTPHASE2ClinicalTrials.gov

1 to 10 of 39

See all 39 trials

NIH grants1,679

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleINHBA papersNewest fiscal year
P30CA016672Cancer Center Support Grant142025
P30CA008748Cancer Center Support Grant132025
P30CA068485Cancer Center Support Grant72025
P30DK058404Molecular and Cellular Basis for Digestive Diseases62025
T32CA009109Cancer Research Training Program: From Molecular Mechanisms to Therapeutic Strategies52025
P30CA043703Case Comprehensive Cancer Center Support Grant42025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202842025
P50CA136393Use of microfluidic tumor cultures to enable clinical trials of therapies for ovarian cancer42025
R01HD032067Transforming growth factor β family signaling pathways in ovarian and uterine biology42025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal42025

1 to 10 of 1,679Source NIH's project files

See all 1,679 nih grants

Papers2,354

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrated Transcriptomic Analysis Identifies a Candidate INHBA/Activin A-Associated Macrophage-MuSC Communication Axis in Human Skeletal Muscle Ageing.Int J Mol Sci202642794710PubTator, text miningPubMed
Construction of an Esophageal Cancer Prognostic Model Based on Mitochondrial Energy Metabolism-Related Genes and Mechanism of INHBA in Promoting Malignant Progression via the Smad2/3 Pathway.Biomolecules202642793200PubTator, text miningPubMed
Integrating Multi-Omics and Machine Learning to Reveal a Prognostic Model for Prostate Cancer Metastatic Recurrence Associated with Epithelial-Mesenchymal Transition Features.Genes (Basel)202642792911PubTator, text miningPubMed
Whole-Exome Sequencing Identifies Candidate Genomic Features Associated with Response to Platinum-Based Chemotherapy and Ixabepilone-Based Treatment in Ovarian Cancer.Int J Mol Sci202642737428PubTator, text miningPubMed
Single-Cell and Bulk Transcriptomic Integration Reveals an Adverse SPP1 Inflammatory TAM State and INHBA as a Candidate Biomarker in Non-Small Cell Lung Cancer Immunotherapy.Int J Genomics202642656806PubTator, text miningPubMed
Identification of Progressive Islet Biomarkers for Type 2 Diabetes by Integrated Transcriptomics and Mendelian Randomization: Alterations Spanning the Normal Glucose Tolerance-Impaired Glucose Tolerance-Type 2 Diabetes Continuum.
Biomedicines202642652231PubTator, text miningPubMed
Correction to "Immune Gene INHBA is Associated With Osteoarthritic Cartilage Damage and May Mediate the Temporal Activation of the TGF-β/p38 MAPK Pathway: Integrating Multiomics Machine Learning and Experimental Validation".
Mediators Inflamm202642644660PubTator, text miningPubMed
Single-cell RNA-seq and spatial transcriptomics characterize CD8+ exhausted T cells in pancreatic ductal adenocarcinoma.iScience202642548877PubTator, text miningPubMed
Systems-Level Mapping of the Tumor Microenvironment Reveals Immune-Mediated Mechanisms and Potential Targets in Platinum-Resistant Ovarian Cancer.Res Sq202642539139PubTator, text miningPubMed
Integrated transcriptomic and machine learning analysis identifies female-associated candidate biomarkers in Idiopathic pulmonary arterial hypertension.Comput Biol Chem202642537335PubTator, text miningPubMed

1 to 10 of 2,354

See all 2,354 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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