Gene · 5028
P2RY1: purinergic receptor P2Y1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. P2RY1: purinergic receptor P2Y1. Genes, record 5028. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5028
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P47900 | P2Y purinoceptor 1 | 373 | 5 | Ensembl, GeneID, HGNC |
Source UniProt
Patents40
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 60482 | P47900 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 3319 | P47900 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 3319 | P47900 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 32814 | P47900 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 32814 | P47900 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 32814 | P47900 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 70040 | P47900 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 2682 | P47900 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 173011 | P47900 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 8055 | P47900 | Espacenet |
1 to 10 of 40
See all 40 patentsDrugs2
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials23
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07122635 | DIQUAFOSOL TETRASODIUM | ClinicalTrials.gov | ||
| NCT07097922 | DIQUAFOSOL TETRASODIUM | ClinicalTrials.gov | ||
| NCT06903884 | DIQUAFOSOL | PHASE3 | ClinicalTrials.gov | |
| NCT06852105 | DIQUAFOSOL TETRASODIUM | ClinicalTrials.gov | ||
| NCT06537349 | DIQUAFOSOL TETRASODIUM | ClinicalTrials.gov | ||
| NCT05694026 | DIQUAFOSOL TETRASODIUM | ClinicalTrials.gov | ||
| NCT05193331 | DIQUAFOSOL TETRASODIUM | ClinicalTrials.gov | ||
| NCT04980144 | DIQUAFOSOL TETRASODIUM | ClinicalTrials.gov | ||
| NCT04548427 | DIQUAFOSOL TETRASODIUM | PHASE3 | ClinicalTrials.gov | |
| NCT03640351 | DIQUAFOSOL | ClinicalTrials.gov |
1 to 10 of 23
See all 23 trialsNIH grants1,328
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | P2RY1 papers | Newest fiscal year |
|---|---|---|---|
| ZIADK031116 | Development of P2Y Receptor Ligands | 45 | 2025 |
| ZIADK031126 | Computer Modeling of G Protein-Coupled Receptors | 17 | 2025 |
| ZIADK031117 | Development of Drugs Acting at Adenosine Receptors | 16 | 2025 |
| P30EY001583 | P30 Core Grant For Vision Research | 7 | 2025 |
| ZIADK031115 | Functionalized Congeners of Bioactive Compounds | 6 | 2025 |
| P01AI045897 | A Tolerance Approach to Xenotransplantation | 5 | 2025 |
| R01HL101972 | Characterization of Coagulation Factor-platelet Interactions: Role of FXI | 5 | 2025 |
| R35GM127121 | Cell signaling by G protein-coupled receptors | 5 | 2025 |
| ZIAAG000295 | Immobilized Proteins In Drug Discovery | 5 | 2025 |
| K12GM068524 | San Diego IRACDA Scholars Program | 4 | 2025 |
1 to 10 of 1,328Source NIH's project files
See all 1,328 nih grantsPapers2,801
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A Boolean Seven-Layer Platelet Decision Model Models Consistently the Logic and Semiquantitatively the Dynamics of Platelet Activation and Inhibition. | Comput Struct Biotechnol J | 2026 | 42819776 | PubTator, text mining | PubMed |
| Structure-based analysis reveals a hydrophobic pocket governing P2Y12 receptor agonist potency and selectivity. | J Enzyme Inhib Med Chem | 2026 | 42786908 | PubTator, text mining | PubMed |
| Residue Interaction Network Reveals Allosteric Pathways Linking Orthosteric and Intracellular Sites in Class A GPCRs. | J Chem Inf Model | 2026 | 42734521 | PubTator, text mining | PubMed |
| COPI Coatomer Regulates Several Steps of HDL Metabolism. | Arterioscler Thromb Vasc Biol | 2026 | 42592650 | PubTator, text mining | PubMed |
| Advances in nucleotide-based P2Y₁ antagonism: implications for cardiovascular therapeutics. | Med Chem Res | 2026 | 42566009 | PubTator, text mining | PubMed |
| Bleeding and Thromboembolic Events With Antiplatelet Agents in Pediatric Heart Disease-An Exploratory Study of the Role of Pharmacogenomics. | Pediatr Blood Cancer | 2026 | 42499276 | PubTator, text mining | PubMed |
| Adenosine triphosphate regulates metastatic behaviors of oral squamous cell carcinoma cells. | Sci Rep | 2026 | 42477432 | PubTator, text mining | PubMed |
| Liver Fibrosis and Purinergic Signaling: Autocrine-Paracrine Role of ATP in Liver Damage. | Int J Mol Sci | 2026 | 42450299 | PubTator, text mining | PubMed |
| Harnessing flavonoids as innovative agents for the modulation of platelet activation and thrombotic disorders. | Mol Biol Rep | 2026 | 42397528 | PubTator, text mining | PubMed |
| Inhibition of (interstitial) P2Y6 receptors attenuates fibrosis progression. | Pflugers Arch | 2026 | 42303751 | PubTator, text mining | PubMed |
1 to 10 of 2,801
See all 2,801 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5028
GET https://conductscience.org/api/genes/v1/5028/patents?page=2