ConductScience.org, home

Gene · 5030

P2RY4: pyrimidinergic receptor P2Y4

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. P2RY4: pyrimidinergic receptor P2Y4. Genes, record 5030. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5030

On this page

Gene

Symbol
P2RY4
HGNC
Name
pyrimidinergic receptor P2Y4
HGNC
NCBI Gene ID
5030
NCBI Gene
HGNC ID
HGNC:8542
HGNC
Ensembl
ENSG00000186912
NCBI Gene
Aliases
NRU, P2P, P2Y4, UNR
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P51582P2Y purinoceptor 43651Ensembl, GeneID, HGNC

Source UniProt

Patents44

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1460523P51582Espacenet
EP 4641201 A22025-10-299727P51582Espacenet
JP 2025529142 A2025-09-043326P51582Espacenet
US 12371689 B22025-07-293326P51582Espacenet
JP 2025517969 A2025-06-129727P51582Espacenet
US 11708610 B22023-07-25545P51582Espacenet
US 11446398 B22022-09-2070209P51582Espacenet
US 11400116 B22022-08-022684P51582Espacenet
JP 2022524081 A2022-04-27173180P51582Espacenet
US 11078247 B22021-08-038057P51582Espacenet

1 to 10 of 44

See all 44 patents

Drugs2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
DIQUAFOSOLCHEMBL221326Pyrimidinergic receptor P2Y4 agonistAGONISTChEMBL
DIQUAFOSOL TETRASODIUMCHEMBL1767408Pyrimidinergic receptor P2Y4 agonistAGONISTChEMBL

Trials23

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07122635DIQUAFOSOL TETRASODIUMClinicalTrials.gov
NCT07097922DIQUAFOSOL TETRASODIUMClinicalTrials.gov
NCT06903884DIQUAFOSOLPHASE3ClinicalTrials.gov
NCT06852105DIQUAFOSOL TETRASODIUMClinicalTrials.gov
NCT06537349DIQUAFOSOL TETRASODIUMClinicalTrials.gov
NCT05694026DIQUAFOSOL TETRASODIUMClinicalTrials.gov
NCT05193331DIQUAFOSOL TETRASODIUMClinicalTrials.gov
NCT04980144DIQUAFOSOL TETRASODIUMClinicalTrials.gov
NCT04548427DIQUAFOSOL TETRASODIUMPHASE3ClinicalTrials.gov
NCT03640351DIQUAFOSOLClinicalTrials.gov

1 to 10 of 23

See all 23 trials

NIH grants403

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleP2RY4 papersNewest fiscal year
ZIADK031116Development of P2Y Receptor Ligands262025
ZIADK031126Computer Modeling of G Protein-Coupled Receptors92025
ZIADK031117Development of Drugs Acting at Adenosine Receptors82025
ZIADK031115Functionalized Congeners of Bioactive Compounds62025
P30CA008748Cancer Center Support Grant22025
P30DK056338Texas Medical Center Digestive Diseases Center22025
R01AI078908Control of Pulmonary Inflammation by Leukotriene E422025
R01DK064324Multiphoton imaging of the juxtaglomerular apparatus22025
K12CA090433PEDIATRIC ONCOLOGY CLINICAL RESEARCH TRAINING PROGRAM12025
K12CA184746MSK Paul Calabresi Career Development Award for Clinical Oncology12025

1 to 10 of 403Source NIH's project files

See all 403 nih grants

Papers961

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Molecular Heterogeneity in Clinically Ambiguous Atopic Dermatitis-Psoriasis Overlap: Compartment-Resolved Transcriptomic Profiling.Allergy202642788674PubTator, text miningPubMed
Microbiota contributes to regulates the external genitalia development through gut-testis axis in male geese.Poult Sci202642617270PubTator, text miningPubMed
Integrating Transcriptomics and 3D Spheroid Models Reveals Microenvironment-Dependent Purinergic Modulation in Hepatocellular Carcinoma.Metabolites202641893304PubTator, text miningPubMed
Identification and Validation of FOXK1-Related Biomarkers in Diabetic Retinopathy.Int J Gen Med202641716682PubTator, text miningPubMed
The purinergic signaling interfaces in breast cancer angiogenesis.Purinergic Signal202641575692PubTator, text miningPubMed
Abnormal purinergic signaling contributes to development of renal cysts in autosomal dominant polycystic kidney disease.Purinergic Signal202641557043PubTator, text miningPubMed
An MILP approach for optimal operation of unbalanced distribution networks through coordinated network reconfiguration and SOP utilization.Sci Rep202541402420PubTator, text miningPubMed
Purinergic Receptors in Dendritic Cells.J Inflamm Res202541049073PubTator, text miningPubMed
Harnessing cell size to separate genetically and functionally distinct dental pulp-derived mesenchymal stromal cell subpopulations.J Biol Eng202540462207PubTator, text miningPubMed
Smart blockchain-powered natural resource asset management and ecological governance countermeasures.Heliyon202539897891PubTator, text miningPubMed

1 to 10 of 961

See all 961 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5030

GET https://conductscience.org/api/genes/v1/5030/patents?page=2