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Gene · 51185

Papers2,935

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Structural basis for selective and potent degradation of IRAK4 by KT-474.Nat Commun202642336816PubTator, text miningPubMed
Molecular Glues Recruiting RNF213 As an E3 Ligase for Targeted Protein Degradation: A Minimal Dibromoacetamide Warhead As a Recruitment Ligand.J Am Chem Soc202642336393PubTator, text miningPubMed
Rational design, molecular characterization and dissociation mechanisms of PROTACs targeting hFAAH.Phys Chem Chem Phys202642333818PubTator, text miningPubMed
TDTAC: a generalized time-dependent torsion angle correlation framework for resolving directional coordination in large biomolecular assemblies.Front Mol Biosci202642311447PubTator, text miningPubMed
On the Scope of DCAF1-Recruiting PROTACs Degrading Protein Kinases.J Med Chem202642304961PubTator, text miningPubMed
Molecular glue degraders of HuR suppress BRAF-mutant colorectal cancer.Nature202642271059PubTator, text miningPubMed
Design, synthesis, and biological evaluation of a potent and selective AURKB degrader.Eur J Med Chem202642263581PubTator, text miningPubMed
LCK-targeting molecular glues overcome resistance to inhibitor-based therapy in T-cell acute lymphoblastic leukemia.Blood202642247310PubTator, text miningPubMed
Research progress and future perspectives in proteolysis-targeting chimeras.Front Pharmacol202642244865PubTator, text miningPubMed
Site-specific combinatorial ubiquitination drives the targeted degradation of plasma membrane proteins.bioRxiv202642244696PubTator, text miningPubMed
An orally active dual CBP/p300 degrader targets core dependencies of multiple myeloma.Cell Rep202642228563PubTator, text miningPubMed
Exploring Novel E3 Ligases and Neosubstrates for Molecular Glue Degraders and Therapeutic Applications in Cancer.Oncol Res202642220438PubTator, text miningPubMed
Discovery of a KLHL41 Ligand for Muscle Specific Protein Degradation.Nat Commun202642191679PubTator, text miningPubMed
Hydrophobic Tag Degraders Overcome Endocrine-Resistant Breast Cancer by Recruiting HSP27-Mediated E3 Ligase Complex for ERα Proteasomal Degradation.Angew Chem Int Ed Engl202642189698PubTator, text miningPubMed
Targeted degradation of SETDB1 by an Aptamer-CRBNL PROTAC as a novel therapeutic strategy for breast cancer.Eur J Med Chem202642176657PubTator, text miningPubMed
Discovery of a selective and effective CRBN-recruiting ATR degrader with strong antitumor activity.Eur J Med Chem202642176651PubTator, text miningPubMed
Pulmonary embolism associated with CRBN-targeting immunomodulatory drugs: a FAERS-based pharmacovigilance and mechanistic analysis.J Thromb Thrombolysis202642176162PubTator, text miningPubMed
Developing orally active estrogen receptor degraders by conjugation of boronic tamoxifen and cereblon ligands.Eur J Med Chem202642172929PubTator, text miningPubMed
Understanding and addressing resistance to IMiDs immunomodulatory compounds in multiple myeloma.FEBS J202642165697PubTator, text miningPubMed
Identification of RET PROTAC with excellent degradation efficiency against medullary thyroid carcinoma.Eur J Med Chem202642161102PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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