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CRBN: cereblon
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Gene · 51185

Papers2,935

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

61 to 80 of 2,935

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TitleJournalYearPMIDFound bySource
From immunomodulators (IMiDs) to cereblon E3 ligase modulator (CELMoDs): the evolution of cereblon modulators in lymphoma therapy.Leuk Lymphoma202642154229PubTator, text miningPubMed
Progress of structurally diverse cereblon (CRBN) ligands and their application in PROTAC degraders.Bioorg Chem202642134201PubTator, text miningPubMed
Mezigdomide reverses T-cell exhaustion through degradation of IKZF1/IKZF3 and reinvigoration of cytokine production pathways.Blood202642118707PubTator, text miningPubMed
Backbone resonance assignment of the Thalidomide Binding Domain (TBD) of cereblon.Biomol NMR Assign202642101529PubTator, text miningPubMed
Advances in SIRT2-Targeted Therapeutics: Structural Insights, Chemical Strategies, and Degrader Technologies.Med Res Rev202642087377PubTator, text miningPubMed
Enabling Access to sp3-Enriched Targeted Protein Degraders via Redox-Neutral Radical Cross-Coupling.Angew Chem Int Ed Engl202642084017PubTator, text miningPubMed
Rational Design of Capsid Protein VP1 Degraders to Overcome Pleconaril Resistance in Inhibiting Enterovirus D68.JACS Au202642063851PubTator, text miningPubMed
Carcinogenicity Risk Assessment of Targeted Protein Degraders.Toxicol Pathol202642051197PubTator, text miningPubMed
Photo-click Proteolysis-Targeting Chimeras Enable Intracellular Generation of PROTACs for Precise Dual Protein Degradation.Angew Chem Int Ed Engl202642026916PubTator, text miningPubMed
Advances in multiple myeloma: key updates from the ASH 2025 meeting.J Hematol Oncol202642021304PubTator, text miningPubMed
Proximity Binding Assay for PROTAC Ternary Complex Analysis.ACS Sens202642011828PubTator, text miningPubMed
Safety considerations for cereblon-recruiting targeted protein degraders.Nat Rev Drug Discov202642009768PubTator, text miningPubMed
Fusion Molecules Between the STAT5b Inhibitor Stafib-2-CR and a Cereblon Ligand.ChemistryOpen202642003497PubTator, text miningPubMed
TNG961 Is a Selective Oral HBS1L Molecular Glue Degrader for the Treatment of FOCAD-Deleted Cancers.Cancer Discov202642001523PubTator, text miningPubMed
Activity of PROTAC MDM2 degrader in primary leukemia cells and PDX models.Leukemia202641986621PubTator, text miningPubMed
DNA-Encoded Library (DEL) Selection Identifies a Distinct DDB1 Ligand Binding Site.ACS Med Chem Lett202641982729PubTator, text miningPubMed
Late Diagnosis of a 3p26.3p25.2 Microduplication in a Young Adult with Mild Neurodevelopmental Features: A Case Report and Literature Review.Mol Syndromol202641937886PubTator, text miningPubMed
Targeting BCL-xL in Myeloid Malignancies: From Inhibitors to PROTAC.J Cell Mol Med202641937490PubTator, text miningPubMed
Optimization of novel quinazolinone derivatives as CRBN E3 ligase modulators for enhanced degradative activity and metabolic stability.Bioorg Chem202641936215PubTator, text miningPubMed
Beyond CRBN and VHL: Parkin driven lysine-based ternary complexes for selective β3-Tubulin degradation.Comput Biol Med202641934939PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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