Gene · 54915
YTHDF1: YTH N6-methyladenosine RNA binding protein F1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. YTHDF1: YTH N6-methyladenosine RNA binding protein F1. Genes, record 54915. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/54915
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9BYJ9 | YTH domain-containing family protein 1 | 559 | 10 | Ensembl, GeneID, HGNC |
Source UniProt
Patents28
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4641201 A2 | 2025-10-29 | 8958 | Q9BYJ9 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 8958 | Q9BYJ9 | Espacenet |
| JP 2025024198 A | 2025-02-19 | 17400 | Q9BYJ9 | Espacenet |
| JP 2023537210 A | 2023-08-31 | 3 | Q9BYJ9 | Espacenet |
| JP 2023522957 A | 2023-06-01 | 9 | Q9BYJ9 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 98265 | Q9BYJ9 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 201236 | Q9BYJ9 | Espacenet |
| US 10677795 B2 | 2020-06-09 | 740 | Q9BYJ9 | Espacenet |
| WO 2020043864 A1 | 2020-03-05 | 2857 | Q9BYJ9 | Espacenet |
| US 9827332 B2 | 2017-11-28 | 17400 | Q9BYJ9 | Espacenet |
1 to 10 of 28
See all 28 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants766
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | YTHDF1 papers | Newest fiscal year |
|---|---|---|---|
| RM1HG008935 | Center for dynamic RNA epitranscriptomes - Renewal | 27 | 2025 |
| R01CA186702 | Mechanisms of epitranscriptomic regulation in cancer | 9 | 2025 |
| P30CA014599 | Cancer Center Support Grant | 8 | 2025 |
| R01AI125416 | Defining the role of the RNA modification N6-methyladenosine during Flaviviridae virus infection | 6 | 2025 |
| P30AI064518 | Center for AIDS Research | 5 | 2025 |
| P30ES027792 | ChicAgo Center for Health and EnvironmenT (CACHET) | 5 | 2025 |
| R35NS111631 | New mechanisms and technologies for understanding post-transcriptional gene regulation in neurons | 5 | 2025 |
| R01GM056927 | Control of Translation in Herpesvirus Infected Cells - Resubmission - 1 | 4 | 2025 |
| T32AI007647 | Training Program in Mechanisms of Virus-Host Interactions | 4 | 2025 |
| P30CA016059 | Massey Cancer Center - Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 766Source NIH's project files
See all 766 nih grantsPapers3,036
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Single residues within the YTHDF intrinsically disordered region control m 6 A-dependent mRNA decay. | bioRxiv | 2026 | 42818126 | PubTator, text mining | PubMed |
| Epitranscriptomic regulation of Notch signaling. | Cell Signal | 2026 | 42800623 | PubTator, text mining | PubMed |
| METTL3‑mediated OTUB1 sustains PD‑L1 protein stability via deubiquitination and promotes immune evasion in oral squamous cell carcinoma. | Mol Cell Biochem | 2026 | 42776380 | PubTator, text mining | PubMed |
| Lactylation and N6-Methyladenosine RNA modification in neuropsychiatric sequelae after intracerebral hemorrhage: a hypothesis-generating metabolic-glial-circuit framework. | Mol Biol Rep | 2026 | 42730969 | PubTator, text mining | PubMed |
| NBR1-Mediated Autophagic Degradation of YTHDF1 Curtails FDX1 Translation to Drive Concurrent Multikinase Inhibitor Resistance and Cuproptosis Tolerance. | Cancer Commun (Lond) | 2026 | 42729649 | PubTator, text mining | PubMed |
| Mutant KRAS-m6A Epitranscriptome Axis Promotes Colorectal Cancer and is a Therapeutic Target. | Adv Sci (Weinh) | 2026 | 42717493 | PubTator, text mining | PubMed |
| Development of m6A Readers for Enhanced Recognition In Vitro via Genetic Code Expansion. | ACS Chem Biol | 2026 | 42715419 | PubTator, text mining | PubMed |
| RNA m⁶A modification and its regulatory factors are altered in granulosa cells from women with PMOS. | J Assist Reprod Genet | 2026 | 42687053 | PubTator, text mining | PubMed |
| YTHDF1-mediated m6A RNA regulation controls cardiomyocyte remodeling through KLF11-HIF1α. | Proc Natl Acad Sci U S A | 2026 | 42679039 | PubTator, text mining | PubMed |
| Single-cell RNA sequencing uncovers m6A regulator-defined T-cell subpopulations and YTHDF1-HSP90AB1-MYC therapeutic axis in T-cell acute lymphoblastic leukemia. | Chin Med J (Engl) | 2026 | 42675534 | PubTator, text mining | PubMed |
1 to 10 of 3,036
See all 3,036 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/54915
GET https://conductscience.org/api/genes/v1/54915/patents?page=2