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Gene · 56413

LTB4R2: leukotriene B4 receptor 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. LTB4R2: leukotriene B4 receptor 2. Genes, record 56413. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/56413

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Gene

Symbol
LTB4R2
HGNC
Name
leukotriene B4 receptor 2
HGNC
NCBI Gene ID
56413
NCBI Gene
HGNC ID
HGNC:19260
HGNC
Ensembl
ENSG00000213906
NCBI Gene
Aliases
BLT2, BLTR2, JULF2, KPG_004, LTB4-R 2, LTB4-R2, NOP9
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9NPC1Leukotriene B4 receptor 23580Ensembl, GeneID, HGNC

Source UniProt

Patents76

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1451650Q9NPC1Espacenet
JP 2026004568 A2026-01-1451651Q9NPC1Espacenet
EP 4640849 A22025-10-292879Q9NPC1Espacenet
EP 4641201 A22025-10-2918680Q9NPC1Espacenet
JP 2025529142 A2025-09-042488Q9NPC1Espacenet
US 12371689 B22025-07-292488Q9NPC1Espacenet
JP 2025519096 A2025-06-242879Q9NPC1Espacenet
JP 2025517969 A2025-06-1218680Q9NPC1Espacenet
US 11446398 B22022-09-2046557Q9NPC1Espacenet
US 11446398 B22022-09-2046560Q9NPC1Espacenet

1 to 10 of 76

See all 76 patents

Drugs2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
CP-195543CHEMBL301829Leukotriene B4 receptor antagonistANTAGONISTChEMBL
NOMACOPANCHEMBL4297928Leukotriene B4 receptor inhibitorINHIBITORChEMBL

Trials9

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT05061771NOMACOPANPHASE3ClinicalTrials.gov
NCT04784455NOMACOPANPHASE32025-05-15ClinicalTrials.gov
NCT04037891NOMACOPANPHASE1/PHASE22025-02-27ClinicalTrials.gov
NCT04035733NOMACOPANPHASE2ClinicalTrials.gov
NCT03829449NOMACOPANPHASE32025-03-12ClinicalTrials.gov
NCT03588026NOMACOPANPHASE3ClinicalTrials.gov
NCT03427060NOMACOPANPHASE22025-05-04ClinicalTrials.gov
NCT02591862NOMACOPANPHASE22023-07-12ClinicalTrials.gov
NCT00424294CP-195543PHASE22014-09-25ClinicalTrials.gov

NIH grants369

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleLTB4R2 papersNewest fiscal year
P30CA036727Buffett Cancer Center Support Grant22025
P30CA068485Cancer Center Support Grant22025
P30DK058404Molecular and Cellular Basis for Digestive Diseases22025
T32GM008315Mechanisms of Trauma-Induced Coagulopathy22025
I01BX001991Molecular Mechanisms of Stellate Cell Activation in Liver Fibrosis12025
I01BX003635Inflammatory and Fibrotic Responses to Malondialdehyde-Acetaldehyde Adducts in Rheumatoid Arthritis12025
I01BX006049Pulmonary aging increases MUC5AC in the airway epithelium, increasing the risk of carcinogenesis12025
IK6BX004205BLR&D Research Career Scientist Award Application12025
K12HD028827Child Health Research Career Development Award (K1-Renewal Yrs 31-35)12025
P20GM103427Nebraska Research Network in Functional Genomics12025

1 to 10 of 369Source NIH's project files

See all 369 nih grants

Papers597

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The 5-Lipoxygenase Pathway in Ovarian Cancer: Mechanisms of Metastasis, Chemoresistance, and Translational Targeting.Int J Womens Health202642763661PubTator, text miningPubMed
12-HHT is associated with epithelial barrier enhancement and reduced inflammatory responses in colon organoids of normoganglionosis in Hirschsprung's disease.PLoS One202642461884PubTator, text miningPubMed
Inhibition of the CYP2E1-19-HETE-BLT2-mediated oxidative injury amplification by FGF21 alleviates myocardial infarction remodeling.Free Radic Biol Med202642456995PubTator, text miningPubMed
Maternal 12-HETE is associated with childhood asthma and the responses to prenatal omega-3 supplementation.Cell Rep Med202641850235PubTator, text miningPubMed
Disturbed LTB4 Metabolism in ILC2s Aggravates Ulcerative Colitis via Intercellular ATP Accumulation.Inflammation202641838192PubTator, text miningPubMed
Regulatory roles of bioactive lipids in vascular homeostasis and remodeling.Med Rev (2021)202641783891PubTator, text miningPubMed
Targeting Fatty Acids in Liver Cancer: Molecular Insights and Drug Approaches.Biomolecules202641750397PubTator, text miningPubMed
12-Hydroxyheptadecatrienoic Acid Predicts Hepatocellular Carcinoma Development During Nucleos(t)ide Analogue Therapy.Cancers (Basel)202641749796PubTator, text miningPubMed
The Intersection of m6A Methylation and Immune Response in PCOS: A Bioinformatics Perspective.Immun Inflamm Dis202641725222PubTator, text miningPubMed
Discovery of Chromone Derivatives as Selective BLT1 Inhibitors for Alleviating Acute Lung Injury and Sepsis.J Med Chem202641696851PubTator, text miningPubMed

1 to 10 of 597

See all 597 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/56413

GET https://conductscience.org/api/genes/v1/56413/patents?page=2