Gene · 56413
LTB4R2: leukotriene B4 receptor 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. LTB4R2: leukotriene B4 receptor 2. Genes, record 56413. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/56413
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9NPC1 | Leukotriene B4 receptor 2 | 358 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents76
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 51650 | Q9NPC1 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 51651 | Q9NPC1 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 2879 | Q9NPC1 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 18680 | Q9NPC1 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2488 | Q9NPC1 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 2488 | Q9NPC1 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 2879 | Q9NPC1 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 18680 | Q9NPC1 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 46557 | Q9NPC1 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 46560 | Q9NPC1 | Espacenet |
1 to 10 of 76
See all 76 patentsDrugs2
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials9
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT05061771 | NOMACOPAN | PHASE3 | ClinicalTrials.gov | |
| NCT04784455 | NOMACOPAN | PHASE3 | 2025-05-15 | ClinicalTrials.gov |
| NCT04037891 | NOMACOPAN | PHASE1/PHASE2 | 2025-02-27 | ClinicalTrials.gov |
| NCT04035733 | NOMACOPAN | PHASE2 | ClinicalTrials.gov | |
| NCT03829449 | NOMACOPAN | PHASE3 | 2025-03-12 | ClinicalTrials.gov |
| NCT03588026 | NOMACOPAN | PHASE3 | ClinicalTrials.gov | |
| NCT03427060 | NOMACOPAN | PHASE2 | 2025-05-04 | ClinicalTrials.gov |
| NCT02591862 | NOMACOPAN | PHASE2 | 2023-07-12 | ClinicalTrials.gov |
| NCT00424294 | CP-195543 | PHASE2 | 2014-09-25 | ClinicalTrials.gov |
NIH grants369
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | LTB4R2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA036727 | Buffett Cancer Center Support Grant | 2 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 2 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 2 | 2025 |
| T32GM008315 | Mechanisms of Trauma-Induced Coagulopathy | 2 | 2025 |
| I01BX001991 | Molecular Mechanisms of Stellate Cell Activation in Liver Fibrosis | 1 | 2025 |
| I01BX003635 | Inflammatory and Fibrotic Responses to Malondialdehyde-Acetaldehyde Adducts in Rheumatoid Arthritis | 1 | 2025 |
| I01BX006049 | Pulmonary aging increases MUC5AC in the airway epithelium, increasing the risk of carcinogenesis | 1 | 2025 |
| IK6BX004205 | BLR&D Research Career Scientist Award Application | 1 | 2025 |
| K12HD028827 | Child Health Research Career Development Award (K1-Renewal Yrs 31-35) | 1 | 2025 |
| P20GM103427 | Nebraska Research Network in Functional Genomics | 1 | 2025 |
1 to 10 of 369Source NIH's project files
See all 369 nih grantsPapers597
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| The 5-Lipoxygenase Pathway in Ovarian Cancer: Mechanisms of Metastasis, Chemoresistance, and Translational Targeting. | Int J Womens Health | 2026 | 42763661 | PubTator, text mining | PubMed |
| 12-HHT is associated with epithelial barrier enhancement and reduced inflammatory responses in colon organoids of normoganglionosis in Hirschsprung's disease. | PLoS One | 2026 | 42461884 | PubTator, text mining | PubMed |
| Inhibition of the CYP2E1-19-HETE-BLT2-mediated oxidative injury amplification by FGF21 alleviates myocardial infarction remodeling. | Free Radic Biol Med | 2026 | 42456995 | PubTator, text mining | PubMed |
| Maternal 12-HETE is associated with childhood asthma and the responses to prenatal omega-3 supplementation. | Cell Rep Med | 2026 | 41850235 | PubTator, text mining | PubMed |
| Disturbed LTB4 Metabolism in ILC2s Aggravates Ulcerative Colitis via Intercellular ATP Accumulation. | Inflammation | 2026 | 41838192 | PubTator, text mining | PubMed |
| Regulatory roles of bioactive lipids in vascular homeostasis and remodeling. | Med Rev (2021) | 2026 | 41783891 | PubTator, text mining | PubMed |
| Targeting Fatty Acids in Liver Cancer: Molecular Insights and Drug Approaches. | Biomolecules | 2026 | 41750397 | PubTator, text mining | PubMed |
| 12-Hydroxyheptadecatrienoic Acid Predicts Hepatocellular Carcinoma Development During Nucleos(t)ide Analogue Therapy. | Cancers (Basel) | 2026 | 41749796 | PubTator, text mining | PubMed |
| The Intersection of m6A Methylation and Immune Response in PCOS: A Bioinformatics Perspective. | Immun Inflamm Dis | 2026 | 41725222 | PubTator, text mining | PubMed |
| Discovery of Chromone Derivatives as Selective BLT1 Inhibitors for Alleviating Acute Lung Injury and Sepsis. | J Med Chem | 2026 | 41696851 | PubTator, text mining | PubMed |
1 to 10 of 597
See all 597 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/56413
GET https://conductscience.org/api/genes/v1/56413/patents?page=2