Gene · 57124
CD248: CD248 molecule
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CD248: CD248 molecule. Genes, record 57124. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/57124
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9HCU0 | Endosialin | 757 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents94
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 40510 | Q9HCU0 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 4538 | Q9HCU0 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 237 | Q9HCU0 | Espacenet |
| EP 4641203 A2 | 2025-10-29 | 147 | Q9HCU0 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 794 | Q9HCU0 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 794 | Q9HCU0 | Espacenet |
| JP 2025517967 A | 2025-06-12 | 147 | Q9HCU0 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 4538 | Q9HCU0 | Espacenet |
| US 12297276 B2 | 2025-05-13 | 1 | Q9HCU0 | Espacenet |
| JP 2025061086 A | 2025-04-10 | 5 | Q9HCU0 | Espacenet |
1 to 10 of 94
See all 94 patentsDrugs1
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action |
|---|---|---|---|
| ONTUXIZUMAB | CHEMBL2364659 | Endosialin inhibitor | INHIBITOR |
Source ChEMBL
Trials5
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT01773434 | ONTUXIZUMAB | PHASE1 | ClinicalTrials.gov | |
| NCT01748721 | ONTUXIZUMAB | PHASE1 | ClinicalTrials.gov | |
| NCT01574716 | ONTUXIZUMAB | PHASE2 | 2019-08-21 | ClinicalTrials.gov |
| NCT01507545 | ONTUXIZUMAB | PHASE2 | 2022-05-06 | ClinicalTrials.gov |
| NCT01335009 | ONTUXIZUMAB | PHASE2 | 2021-09-01 | ClinicalTrials.gov |
NIH grants914
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CD248 papers | Newest fiscal year |
|---|---|---|---|
| R01AI032956 | BETA LACTAMASE MUTATIONS IN ANTIBIOTIC RESISTANCE | 28 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| P30CA014051 | Cancer Center Support (Core) Grant | 4 | 2025 |
| P30CA016520 | Abramson Cancer Center Support Grant | 3 | 2025 |
| P51OD011106 | Wisconsin National Primate Research Center Support | 3 | 2025 |
| R35GM133631 | Characterizing the Effects of Sequence Variability in Molecular Function, Evolution and Design | 3 | 2025 |
| T32AI055449 | Molecular Basis of Infectious Diseases Training Grant | 3 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 2 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 2 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 2 | 2025 |
1 to 10 of 914Source NIH's project files
See all 914 nih grantsPapers1,901
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Correlation analysis of serum PACAP-38, fibulin-3 and TEM1 levels with cardiac function and prognosis in chronic heart failure patients. | J Med Biochem | 2026 | 42780739 | PubTator, text mining | PubMed |
| Coupling continuous directed evolution with base editors identifies combinatorial antibiotic resistance. | Biotechnol Lett | 2026 | 42763377 | PubTator, text mining | PubMed |
| Single-cell RNA sequencing in diabetic foot ulcers: pathogenesis, biomarkers, and translational potential. | Front Clin Diabetes Healthc | 2026 | 42757034 | PubTator, text mining | PubMed |
| CD248: Guardian of Synovial Fibroblast Fate. | Arthritis Rheumatol | 2026 | 42703737 | PubTator, text mining | PubMed |
| Immortalized smooth muscle cells enhance in vitro vasculogenesis. | Angiogenesis | 2026 | 42622755 | PubTator, text mining | PubMed |
| CD55 downregulation identifies a pathogenic CD4+ T cell axis linked to p38 MAPK signaling in rheumatoid arthritis. | J Immunol | 2026 | 42618653 | PubTator, text mining | PubMed |
| From proteome-wide Mendelian randomization and multi-omics integration to functional validation: TGFB3 as a prioritized candidate in gastric adenocarcinoma. | Front Oncol | 2026 | 42518818 | PubTator, text mining | PubMed |
| The CAFs-derived YAP1-periostin axis forms a fibrotic tumor microenvironment to promote metastatic lung tumor growth. | J Transl Med | 2026 | 42469883 | PubTator, text mining | PubMed |
| [Expression of Concern] Endosialin/CD248 may be a potential therapeutic target to prevent the invasion and metastasis in osteosarcoma. | Oncol Lett | 2026 | 42465859 | PubTator, text mining | PubMed |
| Long-term exposure to air pollution, proteomic aging clocks, and liver-related outcomes in Chinese adults. | Environ Res | 2026 | 42419615 | PubTator, text mining | PubMed |
1 to 10 of 1,901
See all 1,901 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/57124
GET https://conductscience.org/api/genes/v1/57124/patents?page=2