Gene · 6263
RYR3: ryanodine receptor 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. RYR3: ryanodine receptor 3. Genes, record 6263. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6263
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q15413 | Ryanodine receptor 3 | 4,870 | 10 | Ensembl, GeneID, HGNC |
Source UniProt
Patents21
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 62520 | Q15413 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 23913 | Q15413 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 3808 | Q15413 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 3808 | Q15413 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 23913 | Q15413 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 35183 | Q15413 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 35183 | Q15413 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 35183 | Q15413 | Espacenet |
| JP 2022141755 A | 2022-09-29 | 316 | Q15413 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 76243 | Q15413 | Espacenet |
1 to 10 of 21
See all 21 patentsDrugs2
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials10
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT06966843 | DANTROLENE | PHASE2/PHASE3 | ClinicalTrials.gov | |
| NCT04134845 | DANTROLENE | PHASE2/PHASE3 | 2025-08-15 | ClinicalTrials.gov |
| NCT03600376 | DANTROLENE SODIUM | PHASE3 | 2021-04-26 | ClinicalTrials.gov |
| NCT03109288 | DANTROLENE | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT02829268 | DANTROLENE SODIUM | PHASE1/PHASE2 | 2024-03-13 | ClinicalTrials.gov |
| NCT02513095 | DANTROLENE SODIUM | PHASE2 | 2017-05-09 | ClinicalTrials.gov |
| NCT01950520 | DANTROLENE | PHASE2 | 2024-10-16 | ClinicalTrials.gov |
| NCT01024972 | DANTROLENE | PHASE1/PHASE2 | 2015-03-05 | ClinicalTrials.gov |
| NCT00964548 | DANTROLENE | PHASE1/PHASE2 | 2012-05-25 | ClinicalTrials.gov |
| NCT00796900 | DANTROLENE | PHASE2/PHASE3 | ClinicalTrials.gov |
NIH grants1,117
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | RYR3 papers | Newest fiscal year |
|---|---|---|---|
| R01ES014901 | Molecular and Cellular Basis of PCB Developmental Neurotoxicity | 8 | 2025 |
| R01HL140934 | Exploring the Molecular Physiology of Atrial Fibrillation | 7 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 5 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| R25NS076445 | Summer Program for Undergraduate Rising Stars (SPURS), a Columbia University biomedical sciences pipeline program | 4 | 2025 |
| P30ES005605 | Environmental Health Sciences Research Center | 3 | 2025 |
| P30ES023513 | UC Davis Environmental Health Sciences Core Center | 3 | 2025 |
| P50AA022537 | Cross-species investigation of gene networks for ethanol-related behaviors | 3 | 2025 |
| T32ES007059 | Advanced Training in Environmental Health Sciences | 3 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 3 | 2025 |
1 to 10 of 1,117Source NIH's project files
See all 1,117 nih grantsPapers1,086
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Cross-Species Transcriptomic Integration Identifies a Conserved Molecular Core and Regulatory ceRNA Network in Duchenne Muscular Dystrophy. | Genes (Basel) | 2026 | 42792910 | PubTator, text mining | PubMed |
| Deciphering the impact of genetic variants on vulnerability to Opioid Use Disorder. | Front Cell Neurosci | 2026 | 42787119 | PubTator, text mining | PubMed |
| Integrated RNA-seq and ATAC-seq analyses reveal muscle development differences between european meat pigeon and shiqi pigeon during embryonic to post-hatching stages. | Front Cell Dev Biol | 2026 | 42780728 | PubTator, text mining | PubMed |
| SHBG and APOA1 as serum biomarkers for low bone mineral density in Mexican postmenopausal women: a random forest-based analysis. | Front Endocrinol (Lausanne) | 2026 | 42620835 | PubTator, text mining | PubMed |
| The First Iranian Patient with West Syndrome Due to a RYR3 Gene Variant: A Case Report and Literature Review. | Arch Iran Med | 2026 | 42604421 | PubTator, text mining | PubMed |
| Serum proteomic signatures and an immune-calcium signaling cascade associated with antipsychotic-related erectile dysfunction in schizophrenia. | Sci Rep | 2026 | 42178376 | PubTator, text mining | PubMed |
| Expanding the genetic spectrum of neurogenetic disorders in moroccan families by exome sequencing: identification of candidate variants in RYR3, POLR3A, and LAMA2. | Mol Biol Rep | 2026 | 42113100 | PubTator, text mining | PubMed |
| The mutational and transcriptional status of RYR in CRC and its indication for prognosis. | Arab J Gastroenterol | 2026 | 42031610 | PubTator, text mining | PubMed |
| Single-Nucleus RNA Sequencing Reveals Muscle Fiber Cell Heterogeneity During Human Skeletal Muscle Aging. | Aging Cell | 2026 | 41979358 | PubTator, text mining | PubMed |
| Distinct mutational signature and clonal evolution in constitutional mismatch repair deficiency-associated high-grade gliomas. | iScience | 2026 | 41797895 | PubTator, text mining | PubMed |
1 to 10 of 1,086
See all 1,086 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6263
GET https://conductscience.org/api/genes/v1/6263/patents?page=2