Gene · 658
BMPR1B: bone morphogenetic protein receptor type 1B
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. BMPR1B: bone morphogenetic protein receptor type 1B. Genes, record 658. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/658
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O00238 | Bone morphogenetic protein receptor type-1B | 502 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents255
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 2369 | O00238 | Espacenet |
| US 12458693 B2 | 2025-11-04 | 102 | O00238 | Espacenet |
| US 12421295 B2 | 2025-09-23 | 34 | O00238 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 586 | O00238 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 586 | O00238 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2369 | O00238 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 9332 | O00238 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 9333 | O00238 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 9336 | O00238 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 9338 | O00238 | Espacenet |
1 to 10 of 255
See all 255 patentsDrugs2
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials4
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT05911477 | DIBOTERMIN ALFA | ClinicalTrials.gov | ||
| NCT01133613 | EPTOTERMIN ALFA | PHASE1 | ClinicalTrials.gov | |
| NCT01111045 | EPTOTERMIN ALFA | PHASE2 | ClinicalTrials.gov | |
| NCT00456157 | EPTOTERMIN ALFA | PHASE1 | ClinicalTrials.gov |
NIH grants1,347
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | BMPR1B papers | Newest fiscal year |
|---|---|---|---|
| P30CA068485 | Cancer Center Support Grant | 9 | 2025 |
| P30CA054174 | Mays Cancer Center at UT Health SA | 7 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 5 | 2025 |
| P30AR069619 | Overall: Resource-based Center for Musculoskeletal Disorders Research (Overall Application) | 3 | 2025 |
| P30CA014236 | Cancer Center Support Grant (CCSG) | 3 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 3 | 2025 |
| R01AA023146 | Role of Beta Spectrin and Smad in Alcohol-Induced Liver and GI Cell Proliferation | 3 | 2025 |
| T90DE021982 | Doctoral and Post-doctoral Training in Craniofacial Biology | 3 | 2025 |
| ZIADE000380 | The role of stem cells in skeletal health and disease | 3 | 2025 |
1 to 10 of 1,347Source NIH's project files
See all 1,347 nih grantsPapers1,863
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Molecular-Genetic Basis of Pulmonary Arterial Hypertension (PAH). | Curr Issues Mol Biol | 2026 | 42353577 | PubTator, text mining | PubMed |
| Insights into Copy Number Variation Architecture in Black Bengal Goat Genome. | Int J Mol Sci | 2026 | 42123621 | PubTator, text mining | PubMed |
| Biomaterials-enabled revelation of sustained p-Smad signaling and abnormal adhesion of leukemia-derived bone marrow stem cells. | Biomaterials | 2026 | 41990418 | PubTator, text mining | PubMed |
| An Intermediate Mesoderm Premyogenic Niche Supports Early Human Myogenic Lineage Progression. | bioRxiv | 2026 | 41958983 | PubTator, text mining | PubMed |
| Receptivity of the human male and female fetal caudal genital ligament to gonadal hormones. | Reproduction | 2026 | 41949886 | PubTator, text mining | PubMed |
| Intrinsic immune properties of carrier MSC impact on the clinical outcome of children with solid tumors receiving oncolytic virotherapy. | Exp Hematol Oncol | 2026 | 41928285 | PubTator, text mining | PubMed |
| Expanding the genetic burden of low-evidence genes in pulmonary arterial hypertension. | Eur J Hum Genet | 2026 | 41882294 | PubTator, text mining | PubMed |
| A single-cell and spatial transcriptomic atlas of human tuberculous constrictive pericardium. | EBioMedicine | 2026 | 41875497 | PubTator, text mining | PubMed |
| Targeting BMP and TAZ/TEAD mechanotransduction pathways impairs acute myeloid leukemia chemoresistance. | Leukemia | 2026 | 41851473 | PubTator, text mining | PubMed |
| Transcriptional coordination in multicellular lineage differentiation during lung organogenesis: deciphering the role of epithelial cells as a microenvironmental regulatory hub. | Front Cell Dev Biol | 2026 | 41799436 | PubTator, text mining | PubMed |
1 to 10 of 1,863
See all 1,863 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/658
GET https://conductscience.org/api/genes/v1/658/patents?page=2