ConductScience.org, home

Gene · 658

BMPR1B: bone morphogenetic protein receptor type 1B

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. BMPR1B: bone morphogenetic protein receptor type 1B. Genes, record 658. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/658

On this page

Gene

Symbol
BMPR1B
HGNC
Name
bone morphogenetic protein receptor type 1B
HGNC
NCBI Gene ID
658
NCBI Gene
HGNC ID
HGNC:1077
HGNC
Ensembl
ENSG00000138696
NCBI Gene
Aliases
ALK-6, ALK6, AMD3, AMDD, BDA1D, BDA2, CDw293
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O00238Bone morphogenetic protein receptor type-1B5021Ensembl, GeneID, HGNC

Source UniProt

Patents255

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-192369O00238Espacenet
US 12458693 B22025-11-04102O00238Espacenet
US 12421295 B22025-09-2334O00238Espacenet
JP 2025529142 A2025-09-04586O00238Espacenet
US 12371689 B22025-07-29586O00238Espacenet
JP 2025517970 A2025-06-122369O00238Espacenet
JP 2025062604 A2025-04-149332O00238Espacenet
JP 2025062604 A2025-04-149333O00238Espacenet
JP 2025062604 A2025-04-149336O00238Espacenet
JP 2025062604 A2025-04-149338O00238Espacenet

1 to 10 of 255

See all 255 patents

Drugs2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
DIBOTERMIN ALFACHEMBL2109171Bone morphogenetic protein receptor type-1B agonistAGONISTChEMBL
EPTOTERMIN ALFACHEMBL2108594Bone morphogenetic protein receptor type-1B agonistAGONISTChEMBL

Trials4

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT05911477DIBOTERMIN ALFAClinicalTrials.gov
NCT01133613EPTOTERMIN ALFAPHASE1ClinicalTrials.gov
NCT01111045EPTOTERMIN ALFAPHASE2ClinicalTrials.gov
NCT00456157EPTOTERMIN ALFAPHASE1ClinicalTrials.gov

NIH grants1,347

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleBMPR1B papersNewest fiscal year
P30CA068485Cancer Center Support Grant92025
P30CA054174Mays Cancer Center at UT Health SA72025
P30CA016672Cancer Center Support Grant62025
UL1TR001863Yale Clinical and Translational Science Award52025
P30AR069619Overall: Resource-based Center for Musculoskeletal Disorders Research (Overall Application)32025
P30CA014236Cancer Center Support Grant (CCSG)32025
P30DK058404Molecular and Cellular Basis for Digestive Diseases32025
R01AA023146Role of Beta Spectrin and Smad in Alcohol-Induced Liver and GI Cell Proliferation32025
T90DE021982Doctoral and Post-doctoral Training in Craniofacial Biology32025
ZIADE000380The role of stem cells in skeletal health and disease32025

1 to 10 of 1,347Source NIH's project files

See all 1,347 nih grants

Papers1,863

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Molecular-Genetic Basis of Pulmonary Arterial Hypertension (PAH).Curr Issues Mol Biol202642353577PubTator, text miningPubMed
Insights into Copy Number Variation Architecture in Black Bengal Goat Genome.Int J Mol Sci202642123621PubTator, text miningPubMed
Biomaterials-enabled revelation of sustained p-Smad signaling and abnormal adhesion of leukemia-derived bone marrow stem cells.Biomaterials202641990418PubTator, text miningPubMed
An Intermediate Mesoderm Premyogenic Niche Supports Early Human Myogenic Lineage Progression.bioRxiv202641958983PubTator, text miningPubMed
Receptivity of the human male and female fetal caudal genital ligament to gonadal hormones.Reproduction202641949886PubTator, text miningPubMed
Intrinsic immune properties of carrier MSC impact on the clinical outcome of children with solid tumors receiving oncolytic virotherapy.Exp Hematol Oncol202641928285PubTator, text miningPubMed
Expanding the genetic burden of low-evidence genes in pulmonary arterial hypertension.Eur J Hum Genet202641882294PubTator, text miningPubMed
A single-cell and spatial transcriptomic atlas of human tuberculous constrictive pericardium.EBioMedicine202641875497PubTator, text miningPubMed
Targeting BMP and TAZ/TEAD mechanotransduction pathways impairs acute myeloid leukemia chemoresistance.Leukemia202641851473PubTator, text miningPubMed
Transcriptional coordination in multicellular lineage differentiation during lung organogenesis: deciphering the role of epithelial cells as a microenvironmental regulatory hub.Front Cell Dev Biol202641799436PubTator, text miningPubMed

1 to 10 of 1,863

See all 1,863 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/658

GET https://conductscience.org/api/genes/v1/658/patents?page=2