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Gene · 6833

ABCC8: ATP binding cassette subfamily C member 8

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. ABCC8: ATP binding cassette subfamily C member 8. Genes, record 6833. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/6833

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
ABCC8
HGNC
Name
ATP binding cassette subfamily C member 8
HGNC
NCBI Gene ID
6833
NCBI Gene
HGNC ID
HGNC:59
HGNC
Ensembl
ENSG00000006071
NCBI Gene
Aliases
ABC36, HHF1, HI, HRINS, MODY12, MRP8, PHHI, PNDM3, SUR, SUR1, SUR1delta2, TNDM2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q09428ATP-binding cassette sub-family C member 81,5818Ensembl, GeneID, HGNC

Source UniProt

Patents20

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4640849 A22025-10-291644Q09428Espacenet
EP 4641201 A22025-10-2911130Q09428Espacenet
JP 2025529142 A2025-09-04205Q09428Espacenet
US 12371689 B22025-07-29205Q09428Espacenet
JP 2025519096 A2025-06-241644Q09428Espacenet
JP 2025517969 A2025-06-1211130Q09428Espacenet
JP 2025062604 A2025-04-147757Q09428Espacenet
JP 2025032204 A2025-03-1123855Q09428Espacenet
EP 4461818 A22024-11-1323855Q09428Espacenet
JP 2023058610 A2023-04-2523855Q09428Espacenet

1 to 10 of 20

See all 20 patents

Drugs15

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ACETOHEXAMIDECHEMBL1589Sulfonylurea receptor 1, Kir6.2 blockerBLOCKERChEMBL
CHLORPROPAMIDECHEMBL498Sulfonylurea receptor 1, Kir6.2 blockerBLOCKERChEMBL
GLICLAZIDECHEMBL427216Sulfonylurea receptor 1, Kir6.2 blockerBLOCKERChEMBL
GLIMEPIRIDECHEMBL1481Sulfonylurea receptor 1, Kir6.2 blockerBLOCKERChEMBL
GLIPIZIDECHEMBL1073Sulfonylurea receptor 1, Kir6.2 blockerBLOCKERChEMBL
GLYBURIDECHEMBL472Sulfonylurea receptor 1, Kir6.2 blockerBLOCKERChEMBL
MITIGLINIDECHEMBL471498Sulfonylurea receptor 1, Kir6.2 blockerBLOCKERChEMBL
MITIGLINIDE CALCIUM DIHYDRATECHEMBL4298005Sulfonylurea receptor 1, Kir6.2 blockerBLOCKERChEMBL
NAMINIDILCHEMBL2105160Sulfonylurea receptors; K-ATP channels openerOPENERChEMBL
NATEGLINIDECHEMBL783Sulfonylurea receptor 1, Kir6.2 blockerBLOCKERChEMBL

1 to 10 of 15

See all 15 drugs

Trials277

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants2,070

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30DK020595Diabetes Research and Training Center332025
P30DK019525University of Pennsylvania Diabetes Research Center142025
P30DK020579Diabetes Research Center142025
P30DK116074Stanford Diabetes Research Center142025
P30DK020593Vanderbilt Diabetes Research Center132025
P30CA068485Cancer Center Support Grant102025
P30DK020541NYR-Diabetes Research Center (NYR-DRC)102025
P30DK020572Michigan Diabetes Research Center (MDRC)102025
R01GM145784Correlating structure and function in KATP channel isoforms92025
UL1TR001863Yale Clinical and Translational Science Award92025

1 to 10 of 2,070Source NIH's project files

See all 2,070 nih grants

Papers4,205

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824987PubTator, text miningPubMed
42821652PubTator, text miningPubMed
42811839PubTator, text miningPubMed
42802766PubTator, text miningPubMed
42784030PubTator, text miningPubMed
42780966PubTator, text miningPubMed
42758052PubTator, text miningPubMed
42753640PubTator, text miningPubMed
42731069PubTator, text miningPubMed
42723843PubTator, text miningPubMed

1 to 10 of 4,205

See all 4,205 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6833

GET https://conductscience.org/api/genes/v1/6833/patents