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Gene · 84444

Papers2,742

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Correction: The disruptor of telomeric silencing 1-like (DOT1L) promotes peritoneal fibrosis through the upregulation and activation of protein tyrosine kinases.Mol Biomed202642247053PubTator, text miningPubMed
DOT1L shapes ncPRC1 target gene repression to maintain germinal center B-cell identity in diffuse large B-cell lymphoma.Blood202642213647PubTator, text miningPubMed
SPARC Drives Tubulointerstitial Fibrosis through Regulating the CBP-DOT1L Pathway.Int J Biol Sci202642212322PubTator, text miningPubMed
Unraveling the layers of epigenetic control in respiratory antiviral defense.J Virol202642159289PubTator, text miningPubMed
From epigenetic scripts to kinase signals: linking DOT1L and RIPK1 in the neurobiology of degeneration.Mol Biol Rep202642133133PubTator, text miningPubMed
Targeting DOT1L Reactivates HERV-K to Drive Cell-Autonomous and Paracrine Senescence in Adenocarcinoma of the Esophagogastric Junction.Cancer Res202642084229PubTator, text miningPubMed
The signaling upstream of DOT1L-mediated H3K79 methylation.Epigenomics202642076975PubTator, text miningPubMed
Mechanism of AF9 (MLLT3)-Partner Dissociation in Mixed-Lineage Leukemia-Rearranged Leukemia.JACS Au202642063817PubTator, text miningPubMed
Inhibition of Dot1L Histone Methyltransferase Expands Bone Injury-Responsive CXCL12+ Stromal Progenitors.bioRxiv202641993436PubTator, text miningPubMed
The Histone-Lysine N-Methyltransferase (KMT2) Family in Health and Disease.MedComm (2020)202641970232PubTator, text miningPubMed
The role of DOT1L in the proliferation and prognosis of gastric cancer.Biosci Rep202641960887PubTator, text miningPubMed
Efficient Generation of Functional TCRαβ+ Cytotoxic T Cells from hiPSCs via Small-Molecule Modulation.bioRxiv202641959015PubTator, text miningPubMed
DOT1L Drives Endothelial-to-Mesenchymal Transition and Fibrotic Vascular Remodeling via H3K79 Methylation.Adv Sci (Weinh)202641933932PubTator, text miningPubMed
Trans-histone crosstalk establishes distinct H3K79 methylation zones with differential transcriptional functions.Nucleic Acids Res202641925229PubTator, text miningPubMed
A conserved mycobacterial nucleomodulin hijacks the host COMPASS complex to reprogram pro-inflammatory transcription and promote intracellular survival.Elife202641915568PubTator, text miningPubMed
Team-Based Long-Term Multidisciplinary Inpatient Neurological Rehabilitation After Surgery of Cerebral Meningioma-Outcome and Confounding Factors.Brain Sci202641892606PubTator, text miningPubMed
Epigenetic Activity of Cancer Therapy Drugs Revealed by HeLa TI Cell-Based Assay.Epigenomes202641892363PubTator, text miningPubMed
A Perturb-seq map of a differentiation hub reveals synergistic vulnerabilities in KMT2A-rearranged acute myeloid leukemia.Leukemia202641882099PubTator, text miningPubMed
CAV1-DOT1L axis in TAM-derived EVs orchestrates VM and sensitises PDAC to combined VM and VEGF targeting.Gut202641856521PubTator, text miningPubMed
Histone methyltransferase DOT1L differentially affects the development of dendritic cell subsets.Life Sci Alliance202641850725PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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