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Gene · 84444

Papers2,742

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Epigenetic and mitoepigenetic regulation in cancer and therapeutic perspectives.Front Pharmacol202641836017PubTator, text miningPubMed
The NLRP3 Inflammasome: Mechanisms of Activation, Regulation, and Therapeutic Opportunities.MedComm (2020)202641799937PubTator, text miningPubMed
The extracellular matrix in inflammation and cancer.Mol Biomed202641787034PubTator, text miningPubMed
Decoding organ fibrosis: mechanistic insights and emerging therapeutic strategies.Signal Transduct Target Ther202641786685PubTator, text miningPubMed
Retinoblastoma: unveiling molecular pathogenesis and pioneering organoid-driven therapeutic innovations.Stem Cell Res Ther202641782059PubTator, text miningPubMed
Recent Advances and Perspectives of Small Molecule Modulators Targeting DOT1L.J Med Chem202641762121PubTator, text miningPubMed
Menin Inhibition in Acute Myeloid MLL Rearranged Leukemias: A New Target for Precision Care.Cancers (Basel)202641749890PubTator, text miningPubMed
Decoding Leukemic Stem Cells in AML: From Identification to Targeted Eradication.Diseases202641745087PubTator, text miningPubMed
Inside the Battle Against Acute Myeloid Leukemia: Biology, Breakthroughs, and Hope.Cells202641744781PubTator, text miningPubMed
Clonal Dynamics and Molecular Heterogeneity of Metaplastic Breast Cancer: Focus on TP53 and PIK3CA Truncal Mutations.Breast Cancer (Dove Med Press)202641737540PubTator, text miningPubMed
Systematic multivariate analysis of chromatin complex dependencies reveals Set1C/COMPASS as a melanoma-enriched epigenetic vulnerability.bioRxiv202641726895PubTator, text miningPubMed
Development of DOT1L-Targeted Protein Degraders for Treating MLL-r Leukemia.J Med Chem202641685902PubTator, text miningPubMed
DOT1L provides transcriptional memory through PRC1.1 antagonism.Nat Cell Biol202641634341PubTator, text miningPubMed
Identification of LncRNAs scaffolding a chromatin-associated gene regulatory complex in breast cancer cells comprising ERα, DOT1L and menin.Cell Commun Signal202641618311PubTator, text miningPubMed
Hijacking the helpers: platelet and neutrophil trafficking in AML and therapeutic exploitation.Exp Hematol Oncol202641593686PubTator, text miningPubMed
A novel dual histone mark reader ZCWPW2 regulates meiotic recombination through lactylation and transcriptional regulation in humans and mice.Nucleic Acids Res202641574437PubTator, text miningPubMed
Stearoyl-CoA desaturase-1 controls the differentiation and antitumoral function of Th9 lymphocytes.J Immunother Cancer202641545305PubTator, text miningPubMed
A Histone Code Functionally Linked to Replicative Senescence.Aging Cell202641482664PubTator, text miningPubMed
Case report and literature review of neurodevelopmental syndrome linked to DOT1L variants.Gene202641475673PubTator, text miningPubMed
Dot1L licenses DNA demethylation to establish regulatory T cell identity.bioRxiv202641427413PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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