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Paper10029

The contribution of extraneuronal uptake to the trachea-blood vessel selectivity of beta-adrenoceptor stimulants in vitro in guinea-pigs.

O'Donnell SR and 1 other. Br J Pharmacol, 1976. Cited by 50 papers, by iCite.

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ConductScience Library. The contribution of extraneuronal uptake to the trachea-blood vessel selectivity of beta-adrenoceptor stimulants in vitro in guinea-pigs. Papers, record 10029. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/10029

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The contribution of extraneuronal uptake to the trachea-blood vessel selectivity of beta-adrenoceptor stimulants in vitro in guinea-pigs.
PubMed
Journal
Br J Pharmacol
PubMed
Year
1976
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
50
iCite
Relative citation ratio, by iCite
2.31
iCite
Revised in PubMed
2019-05-09
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1O'Donnell SRS R
2Wanstall JCJ C

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Adrenergic beta-AgonistsMajor topic
NeuronsMajor topic
TracheaMajor topic
Animals
Drug Synergism
Guinea Pigs
Hindlimb
In Vitro Techniques
Organ Specificity
Phenoxybenzamine
Regional Blood Flow

Source PubMed

References9

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,151,394Cardiovascular and bronchomotor responses to selective beta adrenergic receptor agonists in the anesthetized dog.J Pharmacol Exp Ther1974https://conductscience.org/library/papers/4151394PubMed
24,391,468Analysis of beta receptor drug interactions in isolated rabbit atrium, aorta, stomach and trachea.J Pharmacol Exp Ther1970https://conductscience.org/library/papers/4391468PubMed
34,458,848Potency and selectivity in vitro of compounds related to isoprenaline and orciprenaline on beta-adrenoceptors in the guinea-pig.Br J Pharmacol1974https://conductscience.org/library/papers/4458848PubMed
44,746,746Temperature-dependent supersensitivity of isolated atria to catecholamines.Eur J Pharmacol1973https://conductscience.org/library/papers/4746746PubMed
56,083,116
The potentiation of the responses to noradrenaline and isoprenaline of the guinea-pig isolated tracheal chain preparation by desipramine, cocaine, phentolamine, phenoxybenzamine, guanethidine, metanephrine and cooling.
Br J Pharmacol Chemother1967https://conductscience.org/library/papers/6083116PubMed
64,823,290Studies on carbuterol (SK & F 40383-A), a new selective bronchodilator agent.J Pharmacol Exp Ther1974https://conductscience.org/library/papers/4823290PubMed
75,498,507Species and tissue variation in extraneuronal and neuronal accumulation of noradrenaline.J Physiol1970https://conductscience.org/library/papers/5498507PubMed
85,809,734An uptake of radioactivity from (plus or minus)-3H-isoprenaline and its inhibition by drugs which potentiate the responses to (minus)-isoprenaline in the guinea-pig isolated trachea.Br J Pharmacol1969https://conductscience.org/library/papers/5809734PubMed
94,793,441A histochemical study of extraneuronal accumulation of noradrenaline in the guinea-pig trachea.Br J Pharmacol1973https://conductscience.org/library/papers/4793441PubMed

Cited by19

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 50 citations.

PMIDTitleJournalYearIn PapersSource
24,098,439Extraneuronal monoamine transporter mediates the permissive action of cortisol in the Guinea pig trachea: possible involvement of tracheal chondrocytes.PLoS One2013https://conductscience.org/library/papers/24098439PubMed
7,383,163Affinities of catecholamines for extraneuronal uptake in smooth muscle cells in trachealis muscle of guinea-pig.Naunyn Schmiedebergs Arch Pharmacol1980https://conductscience.org/library/papers/7383163PubMed
7,329,457The extraneuronal O-methylation of 3H-(+)isoprenaline by guinea-pig tracheal rings in vitro.Naunyn Schmiedebergs Arch Pharmacol1981https://conductscience.org/library/papers/7329457PubMed
6,493,357The contribution of diffusion to the entry of catecholamines into guinea-pig trachealis smooth muscle cells.Naunyn Schmiedebergs Arch Pharmacol1984https://conductscience.org/library/papers/6493357PubMed
6,152,829Effect of hypothermia on beta 1-adrenoceptor-mediated relaxation of pig bronchus.Br J Pharmacol1983https://conductscience.org/library/papers/6152829PubMed
6,144,344The classification of beta-adrenoceptors in isolated ring preparations of canine coronary arteries.Br J Pharmacol1984https://conductscience.org/library/papers/6144344PubMed
6,131,720Relaxation of cat trachea by beta-adrenoceptor agonists can be mediated by both beta1- and beta2-adrenoceptors and potentiated by inhibitors of extraneuronal uptake.Br J Pharmacol1983https://conductscience.org/library/papers/6131720PubMed
6,117,344Demonstration of both beta 1- and beta 2-adrenoceptors mediating relaxation of isolated ring preparations of rat pulmonary artery.Br J Pharmacol1981https://conductscience.org/library/papers/6117344PubMed
6,110,457Errors in the measurement of agonist potency-ratios produced by uptake processes: a general model applied to beta-adrenoceptor agonists.Br J Pharmacol1980https://conductscience.org/library/papers/6110457PubMed
6,098,436Alpha- and beta-adrenergic receptor subtypes properties, distribution and regulation.Drugs1984https://conductscience.org/library/papers/6098436PubMed
3,779,217The effects of epithelium removal on the sensitivity of guinea-pig isolated trachealis to bronchodilator drugs.Br J Pharmacol1986https://conductscience.org/library/papers/3779217PubMed
1,982,230Receptors involved in mechanical responses to catecholamines in the circular muscle of guinea-pig stomach treated with meclofenamate.Br J Pharmacol1990https://conductscience.org/library/papers/1982230PubMed
1,884,107Mechanical responses to catecholamines in the longitudinal muscle of guinea-pig gastric fundus.Br J Pharmacol1991https://conductscience.org/library/papers/1884107PubMed
719,273A study on potassium-depolarized tracheal chain preparations from guinea-pigs [proceedings].Br J Pharmacol1978https://conductscience.org/library/papers/719273PubMed
638,385Extraneuronal accumulation of isoprenaline in guinea-pig trachea, atria and uterus: a histochemical and pharmacological study [proceedings].Br J Pharmacol1978https://conductscience.org/library/papers/638385PubMed
367,478The extraneuronal accumulation of isoprenaline in trachea and atria of guinea-pig and cat: a fluorescence histochemical study.Br J Pharmacol1979https://conductscience.org/library/papers/367478PubMed
41,190The importance of choice of agonist in studies designed to predict beta 2 : beta 1 adrenoceptor selectivity of antagonists from pA2 values on guinea-pig trachea and atria.Naunyn Schmiedebergs Arch Pharmacol1979https://conductscience.org/library/papers/41190PubMed
23,882An in vitro comparison of beta-adrenoceptor stimulants on potassium-depolarized uterine preparations from guinea-pigs.Br J Pharmacol1978https://conductscience.org/library/papers/23882PubMed
18,249The use of functional antagonism to determine whether beta-adrenoceptor agonists must have a lower efficacy than isoprenaline to be trachea-atria selective in vitro in guinea-pigs.Br J Pharmacol1977https://conductscience.org/library/papers/18249PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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