Paper · 107196

Gonococcal interactions with polymorphonuclear neutrophils: importance of the phagosome for bactericidal activity.

Densen P and 1 other. J Clin Invest, 1978. Cited by 98 papers, by iCite.

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ConductScience Library. Gonococcal interactions with polymorphonuclear neutrophils: importance of the phagosome for bactericidal activity. Papers, record 107196. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/107196

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Gonococcal interactions with polymorphonuclear neutrophils: importance of the phagosome for bactericidal activity.; PubMed
Journal: J Clin Invest; PubMed
Year: 1978; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/107196/; PubMed
DOI: https://doi.org/10.1172/jci109235; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC371880/; PubMed
The journal: https://conductscience.org/library/journal-index/7802877; PubMed
Citations, by iCite: 98; iCite
Relative citation ratio, by iCite: 2.65; iCite
Revised in PubMed: 2018-11-13; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Densen P	P
2	Mandell GL	G L

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Blood Bactericidal Activity	Major topic
Neisseria gonorrhoeae	Major topic
Neutrophils	Major topic
Phagocytosis	Major topic
Cytochalasin B
Glucuronidase
Hexosephosphates
Humans
Lactoferrin
Microscopy, Electron
Microscopy, Phase-Contrast
Oxygen Consumption

Source PubMed

Grants0

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None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References35

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	1,123,431	H2O2 release from human granulocytes during phagocytosis. I. Documentation, quantitation, and some regulating factors.	J Clin Invest	1975	https://conductscience.org/library/papers/1123431	PubMed
2	1,155,917	Effects of cytochalasin B on the intrcellular bactericidal activity of human neutrophils.	Antimicrob Agents Chemother	1975	https://conductscience.org/library/papers/1155917	PubMed
3	1,180,558	Mechanisms of H2O2 formation by leukocytes. Evidence for a plasma membrane location.	Arch Biochem Biophys	1975	https://conductscience.org/library/papers/1180558	PubMed
4	1,194,852	Studies on the mechanism of phagocytosis. I. Requirements for circumferential attachment of particle-bound ligands to specific receptors on the macrophage plasma membrane.	J Exp Med	1975	https://conductscience.org/library/papers/1194852	PubMed
6	165,258	Neutrophil-mediated tumor cell cytotoxicity: role of the peroxidase system.	J Exp Med	1975	https://conductscience.org/library/papers/165258	PubMed
7	172,446	Fate of human lactoferrin and myeloperoxidase in phagocytizing human neutrophils: effects of immunoglobulin G subclasses and immune complexes coated on latex beads.	Infect Immun	1975	https://conductscience.org/library/papers/172446	PubMed
8	181,401	Elaboration of toxic oxygen by-products by neutrophils in a model of immune complex disease.	J Clin Invest	1976	https://conductscience.org/library/papers/181401	PubMed
9	181,968	Dissociation of phagocytosis, metabolic stimulation and lysosomal enzyme release in human leukocytes.	Agents Actions	1976	https://conductscience.org/library/papers/181968	PubMed
10	185,296	Independent effects of IgG and complement upon human polymorphonuclear leukocyte function.	J Immunol	1976	https://conductscience.org/library/papers/185296	PubMed
11	340,470	Damage to pseudohyphal forms of Candida albicans by neutrophils in the absence of serum in vitro.	J Clin Invest	1978	https://conductscience.org/library/papers/340470	PubMed

1 to 10 of 35

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Cited by49

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 98 citations.

PMID	Title	Journal	Year	In Papers	Source
42,470,645	Neutrophil CEACAMs and the Inflammatory Response to Neisseria gonorrhoeae.	J Innate Immun	2026	https://conductscience.org/library/papers/42470645	PubMed
28,357,376	Gonorrhea - an evolving disease of the new millennium.	Microb Cell	2016	https://conductscience.org/library/papers/28357376	PubMed
24,713,863	Phagocytosis and killing of Staphylococcus aureus by human neutrophils.	J Innate Immun	2014	https://conductscience.org/library/papers/24713863	PubMed
23,374,609	Neisseria gonorrhoeae phagosomes delay fusion with primary granules to enhance bacterial survival inside human neutrophils.	Cell Microbiol	2013	https://conductscience.org/library/papers/23374609	PubMed
21,949,708	Pathogenic Neisseria hitchhike on the uropod of human neutrophils.	PLoS One	2011	https://conductscience.org/library/papers/21949708	PubMed
21,747,795	Resistance of Neisseria gonorrhoeae to neutrophils.	Front Microbiol	2011	https://conductscience.org/library/papers/21747795	PubMed
19,290,914	Resistance of Neisseria gonorrhoeae to non-oxidative killing by adherent human polymorphonuclear leucocytes.	Cell Microbiol	2009	https://conductscience.org/library/papers/19290914	PubMed
19,221,037	Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates.	Blood	2009	https://conductscience.org/library/papers/19221037	PubMed
10,374,695	Negative signaling in health and disease.	Immunol Res	1999	https://conductscience.org/library/papers/10374695	PubMed
9,317,017	Differential response of human monocytes to Neisseria gonorrhoeae variants expressing pili and opacity proteins.	Infect Immun	1997	https://conductscience.org/library/papers/9317017	PubMed

1 to 10 of 49

See all 49 cited by

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
GUSB	2,990	PubTator's text mining	https://conductscience.org/library/genes/2990	NCBI Gene
MPO	4,353	PubTator's text mining	https://conductscience.org/library/genes/4353	NCBI Gene

Drugs0

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None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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