Paper · 14499350

A Ser252Trp [corrected] substitution in mouse fibroblast growth factor receptor 2 (Fgfr2) results in craniosynostosis.

Chen L and 4 others. Bone, 2003. Cited by 137 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. A Ser252Trp [corrected] substitution in mouse fibroblast growth factor receptor 2 (Fgfr2) results in craniosynostosis. Papers, record 14499350. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/14499350

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: A Ser252Trp [corrected] substitution in mouse fibroblast growth factor receptor 2 (Fgfr2) results in craniosynostosis.; PubMed
Journal: Bone; PubMed
Year: 2003; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/14499350/; PubMed
DOI: https://doi.org/10.1016/s8756-3282(03)00222-9; PubMed
The journal: https://conductscience.org/library/journal-index/8504048; PubMed
Citations, by iCite: 137; iCite
Relative citation ratio, by iCite: 2.73; iCite
Revised in PubMed: 2019-09-06; PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Chen L	Lin
2	Li D	Dan
3	Li C	Cuiling
4	Engel A	April
5	Deng CX	Chu-Xia

Source PubMed

Topics22

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Acrocephalosyndactylia	Major topic
Bone Development	Major topic
Proto-Oncogene Proteins c-bcl-2	Major topic
Receptor Protein-Tyrosine Kinases	Major topic
Receptors, Fibroblast Growth Factor	Major topic
Amino Acid Substitution
Animals
Apoptosis
Cell Differentiation
Cell Division
Cranial Sutures
Heterozygote
Mice
Mice, Mutant Strains
Osteoblasts
Phenotype
Proto-Oncogene Proteins
Receptor, Fibroblast Growth Factor, Type 2
Serine
Signal Transduction
Tryptophan
bcl-2-Associated X Protein

Source PubMed

Grants2

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by	Source
			Z01DK056001	NIH	NIH RePORTER
			ZIADK056001	NIH	NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by82

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 137 citations.

PMID	Title	Journal	Year	In Papers	Source
42,633,326	Advances in FGF/FGFR Signaling: Implications for Disease and Therapy.	MedComm (2020)	2026	https://conductscience.org/library/papers/42633326	PubMed
42,049,724	The role of Pth1r in posterior cranium cartilage regulation and craniosynostosis.	Nat Commun	2026	https://conductscience.org/library/papers/42049724	PubMed
41,632,539	Stem cell-associated osteogenic deficiency causes craniofacial deformities with progeroid accumulation of prelamin A.	JCI Insight	2026	https://conductscience.org/library/papers/41632539	PubMed
41,318,657	RAD51B-EZH2 axis as a potential therapeutic target for TNBC through cell fate conversion.	Cell Death Dis	2025	https://conductscience.org/library/papers/41318657	PubMed
41,151,533	FGF receptor 2 signaling in granulosa cells is required for normal female fertility in mice.	Reproduction	2025	https://conductscience.org/library/papers/41151533	PubMed
40,261,605	Insight into Apert Syndrome: Reporting on Six Patients and Increasing Awareness.	Mol Neurobiol	2025	https://conductscience.org/library/papers/40261605	PubMed
39,158,595	New CRISPR/Cas9-based Fgfr2C361Y/+ mouse model of Crouzon syndrome exhibits skull and behavioral abnormalities.	J Mol Med (Berl)	2024	https://conductscience.org/library/papers/39158595	PubMed
39,096,036	Cranial bone microarchitecture in a mouse model for syndromic craniosynostosis.	J Anat	2024	https://conductscience.org/library/papers/39096036	PubMed
38,814,743	Mesenchymal Wnts are required for morphogenetic movements of calvarial osteoblasts during apical expansion.	Development	2024	https://conductscience.org/library/papers/38814743	PubMed
38,602,508	Apical expansion of calvarial osteoblasts and suture patency is dependent on fibronectin cues.	Development	2024	https://conductscience.org/library/papers/38602508	PubMed

1 to 10 of 82

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Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes
FGFR2	2,263	PubTator's text mining	https://conductscience.org/library/genes/2263

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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