Paper15630438
Immune complexes as therapy for autoimmunity.
Clynes R. J Clin Invest, 2005. Cited by 40 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Immune complexes as therapy for autoimmunity. Papers, record 15630438. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/15630438
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
Topics9
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Antigen-Antibody Complex | Major topic |
| Autoimmunity | Major topic |
| Purpura, Thrombocytopenic, Idiopathic | Major topic |
| Animals | |
| Humans | |
| Immunoglobulins, Intravenous | |
| Immunotherapy | |
| Receptors, Fc | |
| Rho(D) Immune Globulin |
Source PubMed
Comments and corrections1
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
| Kind | PMID | Title | In Papers |
|---|---|---|---|
| Comment on | 15,630,455 | Can antibodies with specificity for soluble antigens mimic the therapeutic effects of intravenous IgG in the treatment of autoimmune disease? | https://conductscience.org/library/papers/15630455 |
Source PubMed
References29
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 11,511,777 | Successful treatment of 'malignant rheumatoid arthritis' in Japan with pooled intravenous immunoglobulin. | Rheumatology (Oxford) | 2001 | https://conductscience.org/library/papers/11511777 | PubMed |
| 2 | 15,630,455 | Can antibodies with specificity for soluble antigens mimic the therapeutic effects of intravenous IgG in the treatment of autoimmune disease? | J Clin Invest | 2005 | https://conductscience.org/library/papers/15630455 | PubMed |
| 3 | 11,869,678 | Arthritis critically dependent on innate immune system players. | Immunity | 2002 | https://conductscience.org/library/papers/11869678 | PubMed |
| 4 | 11,911,824 | FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection. | Immunity | 2002 | https://conductscience.org/library/papers/11911824 | PubMed |
| 5 | 11,984,595 | Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. | Nat Med | 2002 | https://conductscience.org/library/papers/11984595 | PubMed |
| 6 | 12,355,445 | Expression of FcgammaRIII is required for development of collagen-induced arthritis. | Eur J Immunol | 2002 | https://conductscience.org/library/papers/12355445 | PubMed |
| 7 | 12,829,590 | Anti-D initially stimulates an Fc-dependent leukocyte oxidative burst and subsequently suppresses erythrophagocytosis via interleukin-1 receptor antagonist. | Blood | 2003 | https://conductscience.org/library/papers/12829590 | PubMed |
| 8 | 14,976,068 | IVIg-mediated amelioration of murine ITP via FcgammaRIIb is not necessarily independent of SHIP-1 and SHP-1 activity. | Blood | 2004 | https://conductscience.org/library/papers/14976068 | PubMed |
| 9 | 11,841,694 | Fc receptors are critical for autoimmune inflammatory damage to the central nervous system in experimental autoimmune encephalomyelitis. | Scand J Immunol | 2002 | https://conductscience.org/library/papers/11841694 | PubMed |
| 10 | 12,421,967 | Development of inflammation in proteoglycan-induced arthritis is dependent on Fc gamma R regulation of the cytokine/chemokine environment. | J Immunol | 2002 | https://conductscience.org/library/papers/12421967 | PubMed |
| 11 | 12,529,736 | Intravenous immunoglobulin mediates an increase in anti-platelet antibody clearance via the FcRn receptor. | Thromb Haemost | 2002 | https://conductscience.org/library/papers/12529736 | PubMed |
| 12 | 12,574,324 | Cutting edge: both activating and inhibitory Fc receptors expressed on mast cells regulate experimental allergic encephalomyelitis disease severity. | J Immunol | 2003 | https://conductscience.org/library/papers/12574324 | PubMed |
| 13 | 12,576,552 | Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination. | Proc Natl Acad Sci U S A | 2003 | https://conductscience.org/library/papers/12576552 | PubMed |
| 14 | 12,506,021 | Monoclonal IgG can ameliorate immune thrombocytopenia in a murine model of ITP: an alternative to IVIG. | Blood | 2003 | https://conductscience.org/library/papers/12506021 | PubMed |
| 15 | 12,705,859 | Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease. | Immunity | 2003 | https://conductscience.org/library/papers/12705859 | PubMed |
| 16 | 12,649,142 | IVIg-mediated amelioration of murine ITP via FcgammaRIIB is independent of SHIP1, SHP-1, and Btk activity. | Blood | 2003 | https://conductscience.org/library/papers/12649142 | PubMed |
| 17 | 10,790,435 | Induction and suppression of collagen-induced arthritis is dependent on distinct fcgamma receptors. | J Exp Med | 2000 | https://conductscience.org/library/papers/10790435 | PubMed |
| 18 | 11,023,519 | Treatment with liposome-encapsulated clodronate as a new strategic approach in the management of immune thrombocytopenic purpura in a mouse model. | Blood | 2000 | https://conductscience.org/library/papers/11023519 | PubMed |
| 19 | 11,161,202 | Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor. | Science | 2001 | https://conductscience.org/library/papers/11161202 | PubMed |
| 20 | 14,984,503 | Intravenous (IV) anti-D and IV immunoglobulin achieve acute platelet increases by different mechanisms: modulation of cytokine and platelet responses to IV anti-D by FcgammaRIIa and FcgammaRIIIa polymorphisms. | Br J Haematol | 2004 | https://conductscience.org/library/papers/14984503 | PubMed |
Cited by17
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 40 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 41,790,328 | The procoagulant effect described in preparations of plasma-derived β2-glycoprotein I (β2GPI) is mediated by contamination with factor XIa. | J Thromb Thrombolysis | 2026 | https://conductscience.org/library/papers/41790328 | PubMed |
| 37,830,631 | Anti-Inflammatory and Immunomodulatory Effect of High-Dose Immunoglobulins in Children: From Approved Indications to Off-Label Use. | Cells | 2023 | https://conductscience.org/library/papers/37830631 | PubMed |
| 37,322,230 | Complement component C1q is an immunological rheostat that regulates Fc:Fc γ R interactions. | Immunogenetics | 2023 | https://conductscience.org/library/papers/37322230 | PubMed |
| 36,480,334 | A novel monoclonal antibody with improved FcγR blocking ability demonstrated non-inferior efficacy compared to IVIG in cynomolgus monkey ITP model at considerably lower dose. | Clin Exp Immunol | 2023 | https://conductscience.org/library/papers/36480334 | PubMed |
| 31,864,410 | Lupus serum IgG induces microglia activation through Fc fragment dependent way and modulated by B-cell activating factor. | J Transl Med | 2019 | https://conductscience.org/library/papers/31864410 | PubMed |
| 31,244,821 | High-Dose Intravenous Immunoglobulin in Skin Autoimmune Disease. | Front Immunol | 2019 | https://conductscience.org/library/papers/31244821 | PubMed |
| 30,120,121 | Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement. | Sci Immunol | 2018 | https://conductscience.org/library/papers/30120121 | PubMed |
| 29,296,968 | A fully recombinant human IgG1 Fc multimer (GL-2045) inhibits complement-mediated cytotoxicity and induces iC3b. | Blood Adv | 2017 | https://conductscience.org/library/papers/29296968 | PubMed |
| 29,204,085 | Immune complex negatively regulates toll-like receptor 3-triggered tumour necrosis factor α production in B cells. | Cent Eur J Immunol | 2017 | https://conductscience.org/library/papers/29204085 | PubMed |
| 28,620,050 | Engineering the fragment crystallizable (Fc) region of human IgG1 multimers and monomers to fine-tune interactions with sialic acid-dependent receptors. | J Biol Chem | 2017 | https://conductscience.org/library/papers/28620050 | PubMed |
| 28,208,757 | Pathogenesis and Therapeutic Mechanisms in Immune Thrombocytopenia (ITP). | J Clin Med | 2017 | https://conductscience.org/library/papers/28208757 | PubMed |
| 27,534,746 | Major methylation alterations on the CpG markers of inflammatory immune associated genes after IVIG treatment in Kawasaki disease. | BMC Med Genomics | 2016 | https://conductscience.org/library/papers/27534746 | PubMed |
| 25,301,934 | Role of B cells and antibodies in acquired immunity against Mycobacterium tuberculosis. | Cold Spring Harb Perspect Med | 2014 | https://conductscience.org/library/papers/25301934 | PubMed |
| 22,382,553 | [Primary immune thrombocytopenia in adults: diagnostics and treatment consensus statement of the Austrian Society of Hematology and Oncology (ÖGHO)]. | Wien Klin Wochenschr | 2012 | https://conductscience.org/library/papers/22382553 | PubMed |
| 19,707,349 | Preventative and therapeutic vaccination to combat an experimental autoimmune kidney disease. | Biologics | 2007 | https://conductscience.org/library/papers/19707349 | PubMed |
| 18,684,965 | Vaccination without autoantigen protects against collagen II-induced arthritis via immune deviation and regulatory T cells. | J Immunol | 2008 | https://conductscience.org/library/papers/18684965 | PubMed |
| 16,469,871 | Efficient inhibition of HIV-1 replication in human immature monocyte-derived dendritic cells by purified anti-HIV-1 IgG without induction of maturation. | Blood | 2006 | https://conductscience.org/library/papers/16469871 | PubMed |
Genes1
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes |
|---|---|---|---|
| RHO | 6,010 | PubTator's text mining | https://conductscience.org/library/genes/6010 |
Source NCBI Gene
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- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
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- ClinicalTrials.govNo license stated
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- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
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- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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