Paper · 16174643
Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk.
Rivera A and 6 others. Hum Mol Genet, 2005. Cited by 643 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk. Papers, record 16174643. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/16174643
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk.
- PubMed
Topics22
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Chromosomes, Human, Pair 10 | Major topic |
| Genetic Predisposition to Disease | Major topic |
| Macular Degeneration | Major topic |
| Base Sequence | |
| Complement Factor H | |
| DNA Primers | |
| Gene Frequency | |
| Genotype | |
| Germany | |
| Haplotypes | |
| Humans | |
| Intracellular Signaling Peptides and Proteins | |
| Linkage Disequilibrium | |
| Membrane Proteins | |
| Molecular Sequence Data | |
| Odds Ratio | |
| Placenta | |
| Polymorphism, Single Nucleotide | |
| Proteins | |
| Retina | |
| Reverse Transcriptase Polymerase Chain Reaction | |
| Sequence Analysis, DNA |
Source PubMed
Grants0
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Trials0
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None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
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References0
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
None in this release.
Cited by352
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 643 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,449,255 | Evaluation of serum semaphorin-3A and interleukin 6 levels in patients with neovascular age-related macular degeneration. | BMC Ophthalmol | 2026 | https://conductscience.org/library/papers/42449255 | PubMed |
| 42,230,802 | Revisiting retinal and macular degeneration in the genomics era. | Nat Rev Genet | 2026 | https://conductscience.org/library/papers/42230802 | PubMed |
| 41,929,012 | Metabolic Analysis of Human Retinal Pigment Epithelium and Choroid Tissue in Aging and Macular Degeneration. | bioRxiv | 2026 | https://conductscience.org/library/papers/41929012 | PubMed |
| 41,898,816 | Precision Is Not Enough: When Tools Outpace Translation in Ocular Gene Therapy. | Genes (Basel) | 2026 | https://conductscience.org/library/papers/41898816 | PubMed |
| 41,750,304 | Molecular Crosstalk in Age-Related Macular Degeneration: Integrating Oxidative Stress, Inflammation, microRNAs, and Genetic Susceptibility Toward Precision Therapeutics. | Biomolecules | 2026 | https://conductscience.org/library/papers/41750304 | PubMed |
| 41,708,012 | Age-related macular degeneration and cerebral amyloid angiopathy have similar pathologies from cholesterol-APOE-amyloid-β-complement mediated inflammation. | Prog Retin Eye Res | 2026 | https://conductscience.org/library/papers/41708012 | PubMed |
| 41,394,566 | Dynamic changes in mRNA isoform usage during human retinal development. | bioRxiv | 2025 | https://conductscience.org/library/papers/41394566 | PubMed |
| 41,203,876 | GWAS SVatalog: a visualization tool to aid fine-mapping of GWAS loci with structural variations. | Heredity (Edinb) | 2026 | https://conductscience.org/library/papers/41203876 | PubMed |
| 40,661,176 | Genotype Prediction from Retinal Fundus Images Using Deep Learning in Eyes with Age-Related Macular Degeneration. | Ophthalmol Sci | 2025 | https://conductscience.org/library/papers/40661176 | PubMed |
| 40,593,839 | Loss of CFHR5 function reduces the risk for age-related macular degeneration. | Nat Commun | 2025 | https://conductscience.org/library/papers/40593839 | PubMed |
1 to 10 of 352
See all 352 cited byGenes3
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| ARMS2 | 387,715 | Swiss-Prot's references | https://conductscience.org/library/genes/387715 | NCBI Gene |
| CFH | 3,075 | PubTator's text mining | https://conductscience.org/library/genes/3075 | NCBI Gene |
| PLEKHA1 | 59,338 | PubTator's text mining | https://conductscience.org/library/genes/59338 | NCBI Gene |
Drugs0
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None in this release.
Data0
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Data dates
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- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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