Paper · 16510331

Mortality after bilateral salpingo-oophorectomy in BRCA1 and BRCA2 mutation carriers: a prospective cohort study.

Domchek SM and 15 others. Lancet Oncol, 2006. Cited by 233 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Mortality after bilateral salpingo-oophorectomy in BRCA1 and BRCA2 mutation carriers: a prospective cohort study. Papers, record 16510331. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/16510331

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Mortality after bilateral salpingo-oophorectomy in BRCA1 and BRCA2 mutation carriers: a prospective cohort study.; PubMed
Journal: Lancet Oncol; PubMed
Year: 2006; PubMed
Publication types: Comparative Study, Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/16510331/; PubMed
DOI: https://doi.org/10.1016/s1470-2045(06)70585-x; PubMed
The journal: https://conductscience.org/library/journal-index/100957246; PubMed
Citations, by iCite: 233; iCite
Relative citation ratio, by iCite: 5.14; iCite
Revised in PubMed: 2024-01-03; PubMed

Authors16

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Domchek SM	Susan M
2	Friebel TM	Tara M
3	Neuhausen SL	Susan L
4	Wagner T	Theresa
5	Evans G	Gareth
6	Isaacs C	Claudine
7	Garber JE	Judy E
8	Daly MB	Mary B
9	Eeles R	Rosalind
10	Matloff E	Ellen

1 to 10 of 16Source PubMed

See all 16 authors

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Breast Neoplasms	Major topic
Genes, BRCA1	Major topic
Genes, BRCA2	Major topic
Ovarian Neoplasms	Major topic
Ovariectomy	Major topic
Adult
Female
Functional Laterality
Germ-Line Mutation
Humans
Middle Aged
Prognosis
Prospective Studies

Source PubMed

Grants3

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by	Source
CA74415	NCI NIH HHS	United States	R01CA074415	PubMed and NIH	NIH RePORTER
N01-CN-6700	NCI NIH HHS	United States		PubMed	PubMed
R01-CA83855	NCI NIH HHS	United States	R01CA083855	PubMed and NIH	NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections1

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

Kind	PMID	Title	In Papers
Comment in	16,510,328	Can bilateral prophylactic salpingo-oophorectomy reduce cancer mortality in carriers of a BRCA1 or BRCA2 mutation?	https://conductscience.org/library/papers/16510328

Source PubMed

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by117

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 233 citations.

PMID	Title	Journal	Year	In Papers	Source
40,974,500	Time trends, uptake, and oncological effects of risk-reducing surgeries in 3067 Danish BRCA1/2 carriers: a population-based study with matched controls.	Breast Cancer Res Treat	2025	https://conductscience.org/library/papers/40974500	PubMed
40,159,529	The patterns and spectrum of BRCA1 and BRCA2 mutations in Iranian breast and ovarian cancer patients.	Fam Cancer	2025	https://conductscience.org/library/papers/40159529	PubMed
39,590,130	Pattern Anlysis of Risk-Reducing Strategies in Unaffected Korean BRCA1/2 Mutation Carriers.	Curr Oncol	2024	https://conductscience.org/library/papers/39590130	PubMed
39,211,401	Hereditary Cancer Genetic Testing: 30 Years of Impact on Cancer Care.	Dela J Public Health	2024	https://conductscience.org/library/papers/39211401	PubMed
39,028,150	The pathologic and clinical outcomes of risk-reducing salpingo-oophorectomy in asymptomatic carriers of homologous recombination repair gene mutation.	J Gynecol Oncol	2025	https://conductscience.org/library/papers/39028150	PubMed
38,854,450	Cutting-edge Treatment for Gynecological Malignancies.	Juntendo Iji Zasshi	2023	https://conductscience.org/library/papers/38854450	PubMed
38,817,104	Basic knowledge for counseling patients undergoing risk-reducing salpingo-oophorectomy.	Obstet Gynecol Sci	2024	https://conductscience.org/library/papers/38817104	PubMed
38,201,529	Prophylactic Interventions for Hereditary Breast and Ovarian Cancer Risks and Mortality in BRCA1/2 Carriers.	Cancers (Basel)	2023	https://conductscience.org/library/papers/38201529	PubMed
38,125,920	Primary Prevention and Early Detection of Hereditary Breast Cancer.	Breast Care (Basel)	2023	https://conductscience.org/library/papers/38125920	PubMed
37,920,853	Pathogenic germline variants in patients with breast cancer: conversations across generations, practices and patients' attitude.	Front Genet	2023	https://conductscience.org/library/papers/37920853	PubMed

1 to 10 of 117

See all 117 cited by

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
BRCA1	672	PubTator's text mining	https://conductscience.org/library/genes/672	NCBI Gene
BRCA2	675	PubTator's text mining	https://conductscience.org/library/genes/675	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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