Paper16632889
Control of the G2/M transition.
Stark GR and 1 other. Mol Biotechnol, 2006. Cited by 233 papers, by iCite.
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ConductScience Library. Control of the G2/M transition. Papers, record 16632889. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/16632889
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
Topics8
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Cell Cycle | Major topic |
| Cell Cycle Proteins | Major topic |
| G2 Phase | Major topic |
| Mitosis | Major topic |
| Animals | |
| DNA Damage | |
| Humans | |
| Models, Biological |
Source PubMed
Grants1
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
| Grant, as the record writes it | Agency | Country | NIH project | Stated by |
|---|---|---|---|---|
| GM 073758 | NIGMS NIH HHS | United States | R15GM073758 | PubMed and NIH |
Source NIH RePORTER
References179
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 10,207,019 | Intra-M phase-promoting factor phosphorylation of cyclin B at the prophase/metaphase transition. | J Biol Chem | 1999 | https://conductscience.org/library/papers/10207019 | PubMed |
| 2 | 1,978,757 | Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. | Science | 1990 | https://conductscience.org/library/papers/1978757 | PubMed |
| 3 | 9,418,909 | Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication. | Mol Cell Biol | 1998 | https://conductscience.org/library/papers/9418909 | PubMed |
| 4 | 1,552,940 | Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. | Nature | 1992 | https://conductscience.org/library/papers/1552940 | PubMed |
| 5 | 11,416,145 | Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. | Mol Cell Biol | 2001 | https://conductscience.org/library/papers/11416145 | PubMed |
| 6 | 14,633,988 | E2F7, a novel E2F featuring DP-independent repression of a subset of E2F-regulated genes. | EMBO J | 2003 | https://conductscience.org/library/papers/14633988 | PubMed |
| 7 | 5,396,222 | Rhabdomyosarcoma in children: epidemiologic study and identification of a familial cancer syndrome. | J Natl Cancer Inst | 1969 | https://conductscience.org/library/papers/5396222 | PubMed |
| 8 | 12,429,704 | Toward maintaining the genome: DNA damage and replication checkpoints. | Annu Rev Genet | 2002 | https://conductscience.org/library/papers/12429704 | PubMed |
| 9 | 2,259,385 | Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome. | Nature | 1990 | https://conductscience.org/library/papers/2259385 | PubMed |
| 10 | 10,051,609 | p53 regulates a G2 checkpoint through cyclin B1. | Proc Natl Acad Sci U S A | 1999 | https://conductscience.org/library/papers/10051609 | PubMed |
| 11 | 10,815,808 | p21Waf1/Cip1/Sdi1-induced growth arrest is associated with depletion of mitosis-control proteins and leads to abnormal mitosis and endoreduplication in recovering cells. | Oncogene | 2000 | https://conductscience.org/library/papers/10815808 | PubMed |
| 12 | 4,361,936 | Control of cell division by very lysine rich histone (F1) phosphorylation. | Nature | 1974 | https://conductscience.org/library/papers/4361936 | PubMed |
| 13 | 2,832,726 | Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life. | Mol Cell Biol | 1988 | https://conductscience.org/library/papers/2832726 | PubMed |
| 14 | 10,570,149 | Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage. | Proc Natl Acad Sci U S A | 1999 | https://conductscience.org/library/papers/10570149 | PubMed |
| 15 | 10,359,610 | The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1. | Mol Biol Cell | 1999 | https://conductscience.org/library/papers/10359610 | PubMed |
| 16 | 11,134,068 | p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks. | J Cell Biol | 2000 | https://conductscience.org/library/papers/11134068 | PubMed |
| 17 | 6,095,116 | Participation of p53 cellular tumour antigen in transformation of normal embryonic cells. | Nature | 1984 | https://conductscience.org/library/papers/6095116 | PubMed |
| 18 | 10,783,254 | Rb function in cell-cycle regulation and apoptosis. | Nat Cell Biol | 2000 | https://conductscience.org/library/papers/10783254 | PubMed |
| 19 | 5,562,852 | The interaction of steroids with Rana pipiens Oocytes in the induction of maturation. | Dev Biol | 1971 | https://conductscience.org/library/papers/5562852 | PubMed |
| 20 | 3,888,732 | Role of protein synthesis and proteases in production and inactivation of maturation-promoting activity during meiotic maturation of starfish oocytes. | Dev Biol | 1985 | https://conductscience.org/library/papers/3888732 | PubMed |
Cited by138
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 233 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 41,969,233 | Discovery of a Novel γ-Glutamylcyclotransferase Inhibitor Plumbagin by Luminescence-Based High-Throughput Screening. | Cancer Sci | 2026 | https://conductscience.org/library/papers/41969233 | PubMed |
| 41,885,615 | The principles of systems biology. | Exp Physiol | 2026 | https://conductscience.org/library/papers/41885615 | PubMed |
| 41,729,423 | Oncogenic role of C11orf86 in ovarian cancer involving hypoxia response and immune modulation. | Discov Oncol | 2026 | https://conductscience.org/library/papers/41729423 | PubMed |
| 41,639,201 | Two paired HPV-59 cervical cancer cell lines with distinct chemoradioresistant phenotypes. | Sci Rep | 2026 | https://conductscience.org/library/papers/41639201 | PubMed |
| 41,593,655 | Crocin and eugenol enhance radiosensitivity in oral squamous cell carcinoma cells via apoptotic pathways and cell cycle regulation. Type of study: in vitro. | BMC Complement Med Ther | 2026 | https://conductscience.org/library/papers/41593655 | PubMed |
| 41,430,012 | Pan-cancer atlas analysis of FANCB and its potential mechanism in cholangiocarcinoma. | Discov Oncol | 2025 | https://conductscience.org/library/papers/41430012 | PubMed |
| 41,318,731 | Cytotoxicity and cell cycle changes in prostate cancer cells with differing PSMA expression and p53 status after treatment with PSMA-targeting radioligand [212Pb]Pb-AB001. | Sci Rep | 2025 | https://conductscience.org/library/papers/41318731 | PubMed |
| 40,833,407 | G-quadruplex stabilization induces DNA breaks in pericentromeric repetitive DNA sequences in B lymphocytes. | Proc Natl Acad Sci U S A | 2025 | https://conductscience.org/library/papers/40833407 | PubMed |
| 40,080,415 | HIV-1 Vif disrupts phosphatase feedback regulation at the kinetochore, leading to a pronounced pseudo-metaphase arrest. | Elife | 2025 | https://conductscience.org/library/papers/40080415 | PubMed |
| 39,966,861 | G2M-checkpoint related immune barrier structure and signature for prognosis and immunotherapy response in hepatocellular carcinoma: insights from spatial transcriptome and machine learning. | J Transl Med | 2025 | https://conductscience.org/library/papers/39966861 | PubMed |
| 39,966,442 | The microRNA-6510 as a potential tumor suppressor in head and neck cancer. | Sci Rep | 2025 | https://conductscience.org/library/papers/39966442 | PubMed |
| 39,736,624 | Transcriptome analysis reveals the anticancer effects of fenbendazole on ovarian cancer: an in vitro and in vivo study. | BMC Cancer | 2024 | https://conductscience.org/library/papers/39736624 | PubMed |
| 38,617,927 | Characterization of a G2M checkpoint-related gene model and subtypes associated with immunotherapy response for clear cell renal cell carcinoma. | Heliyon | 2024 | https://conductscience.org/library/papers/38617927 | PubMed |
| 38,333,638 | Knockdown of TFAP2E results in rapid G2/M transition in oral squamous cell carcinoma cells. | Oncol Lett | 2024 | https://conductscience.org/library/papers/38333638 | PubMed |
| 37,872,260 | The enhanced cytotoxicity on breast cancer cells by Tanshinone I-induced photodynamic effect. | Sci Rep | 2023 | https://conductscience.org/library/papers/37872260 | PubMed |
| 37,774,036 | Transcription factor E4F1 as a regulator of cell life and disease progression. | Sci Adv | 2023 | https://conductscience.org/library/papers/37774036 | PubMed |
| 37,626,666 | Evaluation of Single Dose and Fractionated Dose of I-131 Radiolabeled Nanoparticles for Triple-Negative Breast Cancer Treatment. | Biomedicines | 2023 | https://conductscience.org/library/papers/37626666 | PubMed |
| 37,219,418 | Key elements of cellular senescence involve transcriptional repression of mitotic and DNA repair genes through the p53-p16/RB-E2F-DREAM complex. | Aging (Albany NY) | 2023 | https://conductscience.org/library/papers/37219418 | PubMed |
| 36,293,123 | Chalcone-Acridine Hybrid Suppresses Melanoma Cell Progression via G2/M Cell Cycle Arrest, DNA Damage, Apoptosis, and Modulation of MAP Kinases Activity. | Int J Mol Sci | 2022 | https://conductscience.org/library/papers/36293123 | PubMed |
| 36,276,736 | 3-Deoxysappanchalcone isolated from Caesalpinia sinensis shows anticancer effects on HeLa and PC3 cell lines: invasion, migration, cell cycle arrest, and signaling pathway. | Heliyon | 2022 | https://conductscience.org/library/papers/36276736 | PubMed |
Genes2
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| CDK1 | 983 | PubTator's text mining | https://conductscience.org/library/genes/983 | NCBI Gene |
| TP53 | 7,157 | PubTator's text mining | https://conductscience.org/library/genes/7157 | NCBI Gene |
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
None in this release
- Trials
- Comments and corrections
- Drugs
- Data
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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