Paper1687
Effects of alpha-ketomonocarboxylic acids upon insulin secretion and metabolism of isolated pancreatic islets.
Panten U. Naunyn Schmiedebergs Arch Pharmacol, 1975. Cited by 37 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Effects of alpha-ketomonocarboxylic acids upon insulin secretion and metabolism of isolated pancreatic islets. Papers, record 1687. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/1687
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Effects of alpha-ketomonocarboxylic acids upon insulin secretion and metabolism of isolated pancreatic islets.
- PubMed
Topics18
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Insulin | Major topic |
| Islets of Langerhans | Major topic |
| Keto Acids | Major topic |
| Amino Acids | |
| Animals | |
| Caproates | |
| Caprylates | |
| Female | |
| Insulin Secretion | |
| Male | |
| Mice | |
| Mice, Obese | |
| NAD | |
| NADP | |
| Phenylpyruvic Acids | |
| Propionates | |
| Pyruvates | |
| Valerates |
Source PubMed
References24
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 4,823,515 | Calcium dependency of glucagon secretion from the in vitro perfused rat pancreas. | Endocrinology | 1974 | https://conductscience.org/library/papers/4823515 | PubMed |
| 2 | 4,335,545 | The effect of mannoheptulose on glucose- and pyruvate-stimulated oxygen uptake in normal mouse pancreatic islets. | Biochim Biophys Acta | 1971 | https://conductscience.org/library/papers/4335545 | PubMed |
| 3 | 4,631,835 | Uptake and oxidation of glutamic acid in mammalian pancreatic islets. | Hormones | 1972 | https://conductscience.org/library/papers/4631835 | PubMed |
| 4 | 14,102,663 | A METHOD FOR THE MICRODISSECTION OF INTACT PANCREATIC ISLETS OF MAMMALS. | Acta Endocrinol (Copenh) | 1964 | https://conductscience.org/library/papers/14102663 | PubMed |
| 6 | 5,100,573 | [A method for superfusion of tissue samples for fluorescence measurements]. | Pflugers Arch | 1971 | https://conductscience.org/library/papers/5100573 | PubMed |
| 7 | 11,946,423 | Effects of L-leucine and alpha-ketoisocaproic acid upon insulin secretion and metabolism of isolated pancreatic islets. | FEBS Lett | 1972 | https://conductscience.org/library/papers/11946423 | PubMed |
| 8 | 4,152,382 | Studies on the mechanism of L-leucine-and alpha-ketoisocaproic acid-induced insulin release from perifused isolated pancreatic islets. | Diabetologia | 1974 | https://conductscience.org/library/papers/4152382 | PubMed |
| 9 | 4,306,507 | Flavin and pyridine nucleotide oxidation-reduction changes in perfused rat liver. I. Anoxia and subcellular localization of fluorescent flavoproteins. | J Biol Chem | 1969 | https://conductscience.org/library/papers/4306507 | PubMed |
| 10 | 4,340,564 | State of oxidation-reduction and state of binding in the cytosolic NADH-system as disclosed by equilibration with extracellular lactate-pyruvate in hemoglobin-free perfused rat liver. | Eur J Biochem | 1972 | https://conductscience.org/library/papers/4340564 | PubMed |
| 11 | 5,666,465 | Studies of a simplified plasma insulin immunoassaay using cellulose powder. | Diabetes | 1968 | https://conductscience.org/library/papers/5666465 | PubMed |
| 12 | 4,149,332 | Effect of carbohydrates upon fluorescence of reduced pyridine nucleotides from perifused isolated pancreatic islets. | Diabetologia | 1973 | https://conductscience.org/library/papers/4149332 | PubMed |
| 13 | 5,323,924 | Studies in obese-hyperglycemic mice. | Ann N Y Acad Sci | 1965 | https://conductscience.org/library/papers/5323924 | PubMed |
| 14 | 1,320 | Fluorescence of oxidized flavoproteins from perifused isolated pancreatic islets. | Diabetologia | 1975 | https://conductscience.org/library/papers/1320 | PubMed |
| 15 | 4,331,326 | Effects of glucose and other modifiers of insulin release on the oxidative metabolism of amino acids in micro-dissected pancreatic islets. | Biochem J | 1971 | https://conductscience.org/library/papers/4331326 | PubMed |
| 16 | 5,442,279 | Coinduction of rat liver branched chain alpha-keto acid dehydrogenase activities. | J Biol Chem | 1970 | https://conductscience.org/library/papers/5442279 | PubMed |
| 17 | 13,827,385 | Pancreatic islets in mice with the obese-hyperglycemic syndrome: lack of effect of carbutamide. | Diabetes | 1960 | https://conductscience.org/library/papers/13827385 | PubMed |
| 18 | 4,144,172 | Effect of 2-endo-aminonorbornane-2-carboxylic acid upon insulin secretion and fluorescence of reduced pyridine nucleotides of isolated perifused pancreatic islets. | Naunyn Schmiedebergs Arch Pharmacol | 1973 | https://conductscience.org/library/papers/4144172 | PubMed |
| 19 | 4,337,197 | Cellular localization and characterization of bovine liver branched-chain -keto acid dehydrogenases. | Biochemistry | 1972 | https://conductscience.org/library/papers/4337197 | PubMed |
| 20 | 4,110,546 | In vitro stimulation of insulin release by non-metabolizable, transport-specific amino acids. | Biochim Biophys Acta | 1971 | https://conductscience.org/library/papers/4110546 | PubMed |
| 21 | 14,126,709 | [ANALYTICAL CHROMATOGRAPHY OF AMINO ACIDS IN THE ORDER OF MAGNITUDE OF THE NANOMOL]. | Biochem Z | 1964 | https://conductscience.org/library/papers/14126709 | PubMed |
Cited by9
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 37 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 34,199,454 | What Is the Metabolic Amplification of Insulin Secretion and Is It (Still) Relevant? | Metabolites | 2021 | https://conductscience.org/library/papers/34199454 | PubMed |
| 11,085,930 | Importance of lactate dehydrogenase for the regulation of glycolytic flux and insulin secretion in insulin-producing cells. | Biochem J | 2000 | https://conductscience.org/library/papers/11085930 | PubMed |
| 6,989,358 | 2-oxocarboxylic acids and function of pancreatic islets in obese-hyperglycaemic mice. Insulin secretion in relation to 45Ca uptake and metabolism. | Biochem J | 1980 | https://conductscience.org/library/papers/6989358 | PubMed |
| 6,751,856 | Effects of 4-methyl-2-methylenevalerate, a non-metabolizable analogue of 2-ketoisocaproate, on insulin secretion and metabolism in ob/ob mouse pancreatic islets. | Experientia | 1982 | https://conductscience.org/library/papers/6751856 | PubMed |
| 6,372,787 | Regulation of insulin secretion by energy metabolism in pancreatic B-cell mitochondria. Studies with a non-metabolizable leucine analogue. | Biochem J | 1984 | https://conductscience.org/library/papers/6372787 | PubMed |
| 789,164 | The inhibition of insulin secretion from the perfused rat pancreas after thyroxine treatment. | Diabetologia | 1976 | https://conductscience.org/library/papers/789164 | PubMed |
| 365,176 | Stimulation of proinsulin biosynthesis and insulin release by pyruvate and lactate. | Biochem J | 1978 | https://conductscience.org/library/papers/365176 | PubMed |
| 43,144 | The stimulus--secretion coupling 4-methyl-2-oxopentanoate-induced insulin release. | Biochem J | 1979 | https://conductscience.org/library/papers/43144 | PubMed |
| 43,143 | The metabolism of 4-methyl-2-oxopentanoate in rat pancreatic islets. | Biochem J | 1979 | https://conductscience.org/library/papers/43143 | PubMed |
Genes1
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes |
|---|---|---|---|
| INS | 3,630 | PubTator's text mining | https://conductscience.org/library/genes/3630 |
Source NCBI Gene
Data dates
The date of each source this release read.
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- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
None in this release
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- Trials
- Comments and corrections
- Drugs
- Data
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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