Paper · 17570396

Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.

Dubey VK and 4 others. J Mol Biol, 2007. Cited by 32 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions. Papers, record 17570396. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/17570396

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.; PubMed
Journal: J Mol Biol; PubMed
Year: 2007; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, Non-P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/17570396/; PubMed
DOI: https://doi.org/10.1016/j.jmb.2007.05.065; PubMed
The journal: https://conductscience.org/library/journal-index/2985088R; PubMed
Citations, by iCite: 32; iCite
Relative citation ratio, by iCite: 0.72; iCite
Revised in PubMed: 2007-07-13; PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Dubey VK	Vikash Kumar
2	Lee J	Jihun
3	Somasundaram T	Thayumana
4	Blaber S	Sachiko
5	Blaber M	Michael

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Fibroblast Growth Factor 1	Major topic
Protein Structure, Secondary	Major topic
Protein Structure, Tertiary	Major topic
Amino Acid Sequence
Crystallography, X-Ray
Humans
Models, Molecular
Molecular Sequence Data
Protein Denaturation
Protein Folding
Thermodynamics

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by17

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 32 citations.

PMID	Title	Journal	Year	In Papers	Source
40,257,501	Increased thermal stability of FGF10 leads to ectopic signaling during development.	Cell Mol Life Sci	2025	https://conductscience.org/library/papers/40257501	PubMed
39,236,042	Structural and biochemical investigation into stable FGF2 mutants with novel mutation sites and hydrophobic replacements for surface-exposed cysteines.	PLoS One	2024	https://conductscience.org/library/papers/39236042	PubMed
30,031,837	Probing the role of proline -135 on the structure, stability, and cell proliferation activity of human acidic fibroblast growth factor.	Arch Biochem Biophys	2018	https://conductscience.org/library/papers/30031837	PubMed
29,556,563	Effect of extension of the heparin binding pocket on the structure, stability, and cell proliferation activity of the human acidic fibroblast growth factor.	Biochem Biophys Rep	2018	https://conductscience.org/library/papers/29556563	PubMed
28,432,345	Distant Phe345 mutation compromises the stability and activity of Mycobacterium tuberculosis isocitrate lyase by modulating its structural flexibility.	Sci Rep	2017	https://conductscience.org/library/papers/28432345	PubMed
27,773,526	An S116R Phosphorylation Site Mutation in Human Fibroblast Growth Factor-1 Differentially Affects Mitogenic and Glucose-Lowering Activities.	J Pharm Sci	2016	https://conductscience.org/library/papers/27773526	PubMed
27,019,961	Engineering a Cysteine-Free Form of Human Fibroblast Growth Factor-1 for "Second Generation" Therapeutic Application.	J Pharm Sci	2016	https://conductscience.org/library/papers/27019961	PubMed
24,659,968	Protein comparability assessments and potential applicability of high throughput biophysical methods and data visualization tools to compare physical stability profiles.	Front Pharmacol	2014	https://conductscience.org/library/papers/24659968	PubMed
24,030,023	Protein engineering for cardiovascular therapeutics: untapped potential for cardiac repair.	Circ Res	2013	https://conductscience.org/library/papers/24030023	PubMed
23,133,616	Pharmacokinetic properties of 2nd-generation fibroblast growth factor-1 mutants for therapeutic application.	PLoS One	2012	https://conductscience.org/library/papers/23133616	PubMed

1 to 10 of 17

See all 17 cited by

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes
FGF1	2,246	PubTator's text mining	https://conductscience.org/library/genes/2246

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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