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Paper · 40257501

Increased thermal stability of FGF10 leads to ectopic signaling during development.

Czyrek AA and 34 others. Cell Mol Life Sci, 2025. Cited by 5 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Increased thermal stability of FGF10 leads to ectopic signaling during development. Papers, record 40257501. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/40257501

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Increased thermal stability of FGF10 leads to ectopic signaling during development.
PubMed
Journal
Cell Mol Life Sci
PubMed
Year
2025
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
5
iCite
Relative citation ratio, by iCite
1.52, provisional
iCite
Revised in PubMed
2025-04-24
PubMed

Authors35

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Czyrek AAAleksandra A
2Baran KKarolina
3Hruba EEva
4Horackova AAneta
5Bosakova VVeronika
6Chudzian JJulia
7Fafilek BBohumil
8Laskova VVeronika
9Stepankova VVeronika
10Bednar DDavid

1 to 10 of 35Source PubMed

See all 35 authors

Topics8

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Fibroblast Growth Factor 10Major topic
Signal TransductionMajor topic
Animals
Mice
Humans
Protein Stability
Lung
Receptors, Fibroblast Growth Factor

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References100

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
137,328,066Elucidating Fibroblast Growth Factor-Induced Kinome Dynamics Using Targeted Mass Spectrometry and Dynamic Modeling.Mol Cell Proteomics2023https://conductscience.org/library/papers/37328066PubMed
232,127,497FGF9 and FGF10 activate distinct signaling pathways to direct lung epithelial specification and branching.Sci Signal2020https://conductscience.org/library/papers/32127497PubMed
317,570,396Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.J Mol Biol2007https://conductscience.org/library/papers/17570396PubMed
49,435,295Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction.Development1998https://conductscience.org/library/papers/9435295PubMed
516,597,617Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family.J Biol Chem2006https://conductscience.org/library/papers/16597617PubMed
626,529,612FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants.PLoS Comput Biol2015https://conductscience.org/library/papers/26529612PubMed
717,094,125Effect of polyanions on the structure and stability of repifermin (keratinocyte growth factor-2).J Pharm Sci2007https://conductscience.org/library/papers/17094125PubMed
837,509,496FGF1 Protects MCF-7 Cells against Taltobulin through Both the MEKs/ERKs and PI3K/AKT Signaling Pathway.Biomedicines2023https://conductscience.org/library/papers/37509496PubMed
919,410,332Negative regulation of fibroblast growth factor 10 (FGF-10) by polyoma enhancer activator 3 (PEA3).Eur J Cell Biol2009https://conductscience.org/library/papers/19410332PubMed
1037,920,818Computer-assisted stabilization of fibroblast growth factor FGF-18.Comput Struct Biotechnol J2023https://conductscience.org/library/papers/37920818PubMed

Cited by5

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 5 citations.

PMIDTitleJournalYearIn PapersSource
42,542,977Mechanisms and Manifestations of Ligand Bias in Signaling: Focus on Receptor Tyrosine Kinases.Chem Rev2026https://conductscience.org/library/papers/42542977PubMed
42,439,993Advances in bovine oocyte in vitro maturation: mechanisms and strategies.Vet Res Commun2026https://conductscience.org/library/papers/42439993PubMed
42,387,574Structure-function relationship in FGF signaling: rational design of highly stable FGF2 variants and their effect on cell growth, metabolism, and survival.J Biol Eng2026https://conductscience.org/library/papers/42387574PubMed
41,520,078Engineered fibroblast growth factor 1 variants uncouple glucose-lowering effects from mitogenic activity with therapeutic potential for type 2 diabetes.Mol Biomed2026https://conductscience.org/library/papers/41520078PubMed
40,862,735Fibroblast Growth Factors in Lung Development and Regeneration: Mechanisms and Therapeutic Potential.Cells2025https://conductscience.org/library/papers/40862735PubMed

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
FGF102,255PubTator's text mininghttps://conductscience.org/library/genes/2255NCBI Gene
STAB123,166PubTator's text mininghttps://conductscience.org/library/genes/23166NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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