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Paper · 17693261

Mitochondrial fusion protects against neurodegeneration in the cerebellum.

Chen H and 2 others. Cell, 2007. Cited by 747 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Mitochondrial fusion protects against neurodegeneration in the cerebellum. Papers, record 17693261. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/17693261

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Mitochondrial fusion protects against neurodegeneration in the cerebellum.
PubMed
Journal
Cell
PubMed
Year
2007
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
747
iCite
Relative citation ratio, by iCite
16
iCite
Revised in PubMed
2025-05-29
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Chen HHsiuchen
2McCaffery JMJ Michael
3Chan DCDavid C

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
CerebellumMajor topic
GTP PhosphohydrolasesMajor topic
Membrane FusionMajor topic
MitochondriaMajor topic
Neurodegenerative DiseasesMajor topic
Animals
Intracellular Membranes
Mice
Mice, Inbred C57BL
Mice, Knockout
Purkinje Cells

Source PubMed

Grants5

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
GM062967NIGMS NIH HHSUnited StatesR01GM062967PubMed and NIHNIH RePORTER
S10 RR023454NCRR NIH HHSUnited StatesS10RR023454PubMed and NIHNIH RePORTER
S10 RR022588NCRR NIH HHSUnited StatesS10RR022588PubMed and NIHNIH RePORTER
S10 RR021023NCRR NIH HHSUnited StatesS10RR021023PubMed and NIHNIH RePORTER
S10 RR019409NCRR NIH HHSUnited StatesS10RR019409PubMed and NIHNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by483

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 747 citations.

PMIDTitleJournalYearIn PapersSource
42,959,457Defense and subversion: multilevel mitochondrial quality control and pathway‑specific mitophagy outcomes in Mycobacterium tuberculosis infection.Front Immunol2026https://conductscience.org/library/papers/42959457PubMed
42,938,280Animal Model Selection and Deep Phenotyping in Mitochondrial Genetic Diseases: Connecting Human Variants, Multisystem Pathology, and Preclinical Evidence.Genes (Basel)2026https://conductscience.org/library/papers/42938280PubMed
42,895,508Drosophila dendrites are resilient to adult-onset deficits in mitochondrial dynamics.J Cell Biol2026https://conductscience.org/library/papers/42895508PubMed
42,882,487Mitofusin Activation Delays Aging in Caenorhabditis elegans.Cells2026https://conductscience.org/library/papers/42882487PubMed
42,871,135Lactate promotes mitochondrial biogenesis and fusion via GPR81 to enhance synaptic plasticity-related protein expression in hippocampal cells.Front Cell Dev Biol2026https://conductscience.org/library/papers/42871135PubMed
42,818,327Temporal control of mitochondrial mutagenesis reveals the fate of mtDNA mutations with age.bioRxiv2026https://conductscience.org/library/papers/42818327PubMed
42,588,565Lipidomics Based on HILIC-ESI-HRMS Reveal Subtle Changes in the Mitochondrial Phospholipidome of Mouse Embryonic Fibroblasts Expressing Pathogenic Variants of Human OPA1 Protein.Molecules2026https://conductscience.org/library/papers/42588565PubMed
42,521,674Mitochondrial quality control in health and disease: mechanisms and therapeutic targets.Signal Transduct Target Ther2026https://conductscience.org/library/papers/42521674PubMed
42,455,671Mitofusin-2 in ventral striatal D1 neurons regulates effort-based motivation through sex-specific mitochondrial-synaptic reprogramming.Proc Natl Acad Sci U S A2026https://conductscience.org/library/papers/42455671PubMed
42,378,301Tau protein as a regulator of mitochondrial function and dynamics.Proc Natl Acad Sci U S A2026https://conductscience.org/library/papers/42378301PubMed

1 to 10 of 483

See all 483 cited by

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
MFN155,669PubTator's text mininghttps://conductscience.org/library/genes/55669NCBI Gene
MFN29,927PubTator's text mininghttps://conductscience.org/library/genes/9927NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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