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Paper · 18239126

Cancer proliferation gene discovery through functional genomics.

Schlabach MR and 16 others. Science, 2008. Cited by 306 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Cancer proliferation gene discovery through functional genomics. Papers, record 18239126. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/18239126

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Cancer proliferation gene discovery through functional genomics.
PubMed
Journal
Science
PubMed
Year
2008
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.
PubMed
Citations, by iCite
306
iCite
Relative citation ratio, by iCite
4.72
iCite
Revised in PubMed
2025-05-29
PubMed

Authors17

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Schlabach MRMichael R
2Luo JJi
3Solimini NLNicole L
4Hu GGuang
5Xu QQikai
6Li MZMamie Z
7Zhao ZZhenming
8Smogorzewska AAgata
9Sowa MEMathew E
10Ang XLXiaolu L

1 to 10 of 17Source PubMed

See all 17 authors

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Breast NeoplasmsMajor topic
Cell ProliferationMajor topic
Colonic NeoplasmsMajor topic
Genes, NeoplasmMajor topic
GenomicsMajor topic
Cell Line
Cell Line, Tumor
Cell Survival
Gene Library
Genetic Vectors
Genome, Human
Humans
MicroRNAs
Oligonucleotide Array Sequence Analysis
RNA, Small Interfering
Retroviridae

Source PubMed

Grants6

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
P01 CA013106NCI NIH HHSUnited StatesP01CA013106PubMed and NIHNIH RePORTER
F31 NS054507NINDS NIH HHSUnited StatesF31NS054507PubMed and NIHNIH RePORTER
T32CA09216NCI NIH HHSUnited StatesT32CA009216PubMed and NIHNIH RePORTER
T32 CA009216NCI NIH HHSUnited StatesT32CA009216PubMed and NIHNIH RePORTER
Howard Hughes Medical InstituteUnited StatesPubMedPubMed
R01 AG011085NIA NIH HHSUnited StatesR01AG011085PubMed and NIHNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References17

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
115,042,092A large-scale RNAi screen in human cells identifies new components of the p53 pathway.Nature2004https://conductscience.org/library/papers/15042092PubMed
214,704,432In vivo activation of the p53 pathway by small-molecule antagonists of MDM2.Science2004https://conductscience.org/library/papers/14704432PubMed
315,960,972A genetic screen for candidate tumor suppressors identifies REST.Cell2005https://conductscience.org/library/papers/15960972PubMed
415,960,973A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity.Cell2005https://conductscience.org/library/papers/15960973PubMed
516,200,064Probing tumor phenotypes using stable and regulated synthetic microRNA precursors.Nat Genet2005https://conductscience.org/library/papers/16200064PubMed
616,572,121A loss-of-function RNA interference screen for molecular targets in cancer.Nature2006https://conductscience.org/library/papers/16572121PubMed
717,417,629A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.Nat Cell Biol2007https://conductscience.org/library/papers/17417629PubMed
817,558,397The ubiquitin-specific protease USP28 is required for MYC stability.Nat Cell Biol2007https://conductscience.org/library/papers/17558397PubMed
915,042,091A resource for large-scale RNA-interference-based screens in mammals.Nature2004https://conductscience.org/library/papers/15042091PubMed
1017,889,643Non-oncogene addiction and the stress phenotype of cancer cells.Cell2007https://conductscience.org/library/papers/17889643PubMed

Cited by221

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 306 citations.

PMIDTitleJournalYearIn PapersSource
41,402,283A pooled Cell Painting CRISPR screening platform enables de novo inference of gene function by self-supervised deep learning.Nat Commun2025https://conductscience.org/library/papers/41402283PubMed
40,517,166Advances in molecular pathology and therapy of non-small cell lung cancer.Signal Transduct Target Ther2025https://conductscience.org/library/papers/40517166PubMed
40,028,2913D bioprinting for the construction of drug testing models-development strategies and regulatory concerns.Front Bioeng Biotechnol2025https://conductscience.org/library/papers/40028291PubMed
39,347,709UBA1 dysfunction in VEXAS and cancer.Oncotarget2024https://conductscience.org/library/papers/39347709PubMed
38,431,617RTF2 controls replication repriming and ribonucleotide excision at the replisome.Nat Commun2024https://conductscience.org/library/papers/38431617PubMed
37,712,571Precision Oncology Comes of Age: Designing Best-in-Class Small Molecules by Integrating Two Decades of Advances in Chemistry, Target Biology, and Data Science.Cancer Discov2023https://conductscience.org/library/papers/37712571PubMed
37,202,533Identification of acquired Notch3 dependency in metastatic Head and Neck Cancer.Commun Biol2023https://conductscience.org/library/papers/37202533PubMed
34,839,558SUMOylation regulates Rb hyperphosphorylation and inactivation in uveal melanoma.Cancer Sci2022https://conductscience.org/library/papers/34839558PubMed
34,529,489The adaptive immune system is a major driver of selection for tumor suppressor gene inactivation.Science2021https://conductscience.org/library/papers/34529489PubMed
34,495,459Distinct genetic landscape and a low response to doxorubicin in a luminal-A breast cancer cell line of Pakistani origin.Mol Biol Rep2021https://conductscience.org/library/papers/34495459PubMed

1 to 10 of 221

See all 221 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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