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Paper · 20007845

KRAS mutation: comparison of testing methods and tissue sampling techniques in colon cancer.

Franklin WA and 5 others. J Mol Diagn, 2010. Cited by 98 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. KRAS mutation: comparison of testing methods and tissue sampling techniques in colon cancer. Papers, record 20007845. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/20007845

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
KRAS mutation: comparison of testing methods and tissue sampling techniques in colon cancer.
PubMed
Journal
J Mol Diagn
PubMed
Year
2010
PubMed
Publication types
Comparative Study, Evaluation Study, Journal Article, Research Support, N.I.H., Extramural
PubMed
Citations, by iCite
98
iCite
Relative citation ratio, by iCite
2.5
iCite
Revised in PubMed
2024-01-03
PubMed

Authors6

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Franklin WAWilbur A
2Haney JJerry
3Sugita MMichio
4Bemis LLynne
5Jimeno AAntonio
6Messersmith WAWells A

Source PubMed

Topics18

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
CarcinomaMajor topic
Colonic NeoplasmsMajor topic
DNAMajor topic
Genetic TestingMajor topic
MutationMajor topic
Proto-Oncogene ProteinsMajor topic
ras ProteinsMajor topic
Carcinoma, Non-Small-Cell Lung
Cell Line, Tumor
DNA Mutational Analysis
DNA Primers
Formaldehyde
Humans
Nucleic Acid Denaturation
Paraffin Embedding
Proto-Oncogene Proteins p21(ras)
Sensitivity and Specificity
Tissue Fixation

Source PubMed

Grants4

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
P30 CA046934NCI NIH HHSUnited StatesP30CA046934PubMed and NIHNIH RePORTER
U01 CA085070NCI NIH HHSUnited StatesU01CA085070PubMed and NIHNIH RePORTER
U01-CA85070NCI NIH HHSUnited StatesU01CA085070PubMed and NIHNIH RePORTER
P30-CA046934NCI NIH HHSUnited StatesP30CA046934PubMed and NIHNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References27

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
111,000,267Mode of action and application of Scorpion primers to mutation detection.Nucleic Acids Res2000https://conductscience.org/library/papers/11000267PubMed
216,043,828
Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib.
J Clin Oncol2005https://conductscience.org/library/papers/16043828PubMed
310,429,248Detection of PCR products using self-probing amplicons and fluorescence.Nat Biotechnol1999https://conductscience.org/library/papers/10429248PubMed
417,875,767Epidermal growth factor receptor mutation detection using high-resolution melting analysis predicts outcomes in patients with advanced non small cell lung cancer treated with gefitinib.Clin Cancer Res2007https://conductscience.org/library/papers/17875767PubMed
511,106,325K-ras point mutation detection in lung cancer: comparison of two approaches to somatic mutation detection using ARMS allele-specific amplification.Clin Chem2000https://conductscience.org/library/papers/11106325PubMed
618,495,026High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies.BMC Cancer2008https://conductscience.org/library/papers/18495026PubMed
79,216,447Methods for detection of point mutations: performance and quality assessment. IFCC Scientific Division, Committee on Molecular Biology Techniques.Clin Chem1997https://conductscience.org/library/papers/9216447PubMed
819,339,720Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer.N Engl J Med2009https://conductscience.org/library/papers/19339720PubMed
92,547,647The molecular genetics of human lung cancer.Eur Respir J1989https://conductscience.org/library/papers/2547647PubMed
1012,600,951Amplicon melting analysis with labeled primers: a closed-tube method for differentiating homozygotes and heterozygotes.Clin Chem2003https://conductscience.org/library/papers/12600951PubMed

1 to 10 of 27

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Cited by48

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 98 citations.

PMIDTitleJournalYearIn PapersSource
41,514,544Advances and Challenges in KRAS Mutation Detection and Clinical Implications.Cancers (Basel)2025https://conductscience.org/library/papers/41514544PubMed
39,367,162KRAS mutations detection methodology: from RFLP to CRISPR/Cas based methods.Funct Integr Genomics2024https://conductscience.org/library/papers/39367162PubMed
38,571,493Antineoplastic effect of compounds C14 and P8 on TNBC and radioresistant TNBC cells by stabilizing the K-Ras4BG13D/PDE6δ complex.Front Oncol2024https://conductscience.org/library/papers/38571493PubMed
37,097,304Combining the amplification refractory mutation system and high-resolution melting analysis for KRAS mutation detection in clinical samples.Anal Bioanal Chem2023https://conductscience.org/library/papers/37097304PubMed
34,918,209Untangling the KRAS mutated lung cancer subsets and its therapeutic implications.Mol Biomed2021https://conductscience.org/library/papers/34918209PubMed
32,648,137Current therapy of advanced colorectal cancer according to RAS/RAF mutational status.Cancer Metastasis Rev2020https://conductscience.org/library/papers/32648137PubMed
30,949,599KRAS and NRAS pyrosequencing screening in Tunisian colorectal cancer patients in 2015.Heliyon2019https://conductscience.org/library/papers/30949599PubMed
29,658,583Intraductal papillary mucinous neoplasms of the pancreas: Clinical association with KRAS.Mol Med Rep2018https://conductscience.org/library/papers/29658583PubMed
29,304,017Genotyping of KRAS Mutational Status by the In-Check Lab-on-Chip Platform.Sensors (Basel)2018https://conductscience.org/library/papers/29304017PubMed
29,137,388Rapid and accurate detection of KRAS mutations in colorectal cancers using the isothermal-based optical sensor for companion diagnostics.Oncotarget2017https://conductscience.org/library/papers/29137388PubMed

1 to 10 of 48

See all 48 cited by

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
EGFR1,956PubTator's text mininghttps://conductscience.org/library/genes/1956NCBI Gene
KRAS3,845PubTator's text mininghttps://conductscience.org/library/genes/3845NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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