Paper · 205166

Insulin, glucagon, and somatostatin secretion in the regulation of metabolism.

Unger RH and 2 others. Annu Rev Physiol, 1978. Cited by 213 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Insulin, glucagon, and somatostatin secretion in the regulation of metabolism. Papers, record 205166. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/205166

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Insulin, glucagon, and somatostatin secretion in the regulation of metabolism.; PubMed
Journal: Annu Rev Physiol; PubMed
Year: 1978; PubMed
Publication types: Journal Article, Review; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/205166/; PubMed
DOI: https://doi.org/10.1146/annurev.ph.40.030178.001515; PubMed
The journal: https://conductscience.org/library/journal-index/0370600; PubMed
Citations, by iCite: 213; iCite
Relative citation ratio, by iCite: 7.09; iCite
Revised in PubMed: 2013-11-21; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Unger RH	R H
2	Dobbs RE	R E
3	Orci L	L

Source PubMed

Topics20

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Glucagon	Major topic
Insulin	Major topic
Islets of Langerhans	Major topic
Metabolism	Major topic
Somatostatin	Major topic
Adenoma, Islet Cell
Animals
Birds
Cell Membrane
Diabetes Mellitus
Dogs
Glucose
Guinea Pigs
Haplorhini
Humans
Molecular Conformation
Pancreatic Neoplasms
Rats
Species Specificity
Swine

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by52

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 213 citations.

PMID	Title	Journal	Year	In Papers	Source
39,218,857	Alterations of pleiotropic neuropeptide-receptor gene couples in Cetacea.	BMC Biol	2024	https://conductscience.org/library/papers/39218857	PubMed
38,459,816	Histology and immunofluorescent study of the pancreas in lovebird (Agapornis personatus).	Vet Med Sci	2024	https://conductscience.org/library/papers/38459816	PubMed
36,941,447	Mammalian models of diabetes mellitus, with a focus on type 2 diabetes mellitus.	Nat Rev Endocrinol	2023	https://conductscience.org/library/papers/36941447	PubMed
35,136,093	Four features of temporal patterns characterize similarity among individuals and molecules by glucose ingestion in humans.	NPJ Syst Biol Appl	2022	https://conductscience.org/library/papers/35136093	PubMed
33,367,814	Human Glucagon Expression Is under the Control of miR-320a.	Endocrinology	2021	https://conductscience.org/library/papers/33367814	PubMed
32,425,629	Nonclassical Islet Peptides: Pancreatic and Extrapancreatic Actions.	Clin Med Insights Endocrinol Diabetes	2019	https://conductscience.org/library/papers/32425629	PubMed
32,184,874	Designing an Engineered Construct Gene Sensitive to Carbohydrate In-vitro and Candidate for Human Insulin Gene Therapy In-vivo.	Iran J Pharm Res	2019	https://conductscience.org/library/papers/32184874	PubMed
31,073,338	Chiral micellar electrokinetic chromatographic separation for determination of L- and D-primary amines released from murine islets of Langerhans.	Anal Methods	2019	https://conductscience.org/library/papers/31073338	PubMed
28,213,398	FoxO integration of insulin signaling with glucose and lipid metabolism.	J Endocrinol	2017	https://conductscience.org/library/papers/28213398	PubMed
27,752,182	Introducing a New Experimental Islet Transplantation Model using Biomimetic Hydrogel and a Simple High Yield Islet Isolation Technique.	Iran Biomed J	2017	https://conductscience.org/library/papers/27752182	PubMed

1 to 10 of 52

See all 52 cited by

Genes3

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
GCG	2,641	PubTator's text mining	https://conductscience.org/library/genes/2641	NCBI Gene
INS	3,630	PubTator's text mining	https://conductscience.org/library/genes/3630	NCBI Gene
SST	6,750	PubTator's text mining	https://conductscience.org/library/genes/6750	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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