Paper · 209176

Synaptic delay in the heart: an ionophoretic study.

Hill-Smith I and 1 other. J Physiol, 1978. Cited by 111 papers, by iCite.

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ConductScience Library. Synaptic delay in the heart: an ionophoretic study. Papers, record 209176. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/209176

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Synaptic delay in the heart: an ionophoretic study.; PubMed
Journal: J Physiol; PubMed
Year: 1978; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/209176/; PubMed
DOI: https://doi.org/10.1113/jphysiol.1978.sp012329; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC1282600/; PubMed
The journal: https://conductscience.org/library/journal-index/0266262; PubMed
Citations, by iCite: 111; iCite
Relative citation ratio, by iCite: 3.69; iCite
Revised in PubMed: 2019-05-09; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Hill-Smith I	I
2	Purves RD	R D

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Acetylcholine	Major topic
Carbachol	Major topic
Catecholamines	Major topic
Heart	Major topic
Action Potentials
Animals
Cyclic AMP
Diffusion
Female
Heart Ventricles
Male
Rats
Receptors, Neurotransmitter
Synaptic Transmission
Time Factors
Ventricular Function

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References49

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
3	13,861,024	Chronotropic response following direct electrical stimulation of the isolated sinoatrial node: a pharmacologic evaluation.	J Pharmacol Exp Ther	1962	https://conductscience.org/library/papers/13861024	PubMed
6	14,035,888	Determination of iontophoretic release of acetylcholine from micropipettes.	J Physiol	1963	https://conductscience.org/library/papers/14035888	PubMed
7	13,955,375	An electrophysiological investigation of mammalian motor nerve terminals.	J Physiol	1963	https://conductscience.org/library/papers/13955375	PubMed
8	13,675,766	Amino acid metabolism in mammalian cell cultures.	Science	1959	https://conductscience.org/library/papers/13675766	PubMed
9	14,394,097	Production of membrane potential changes in the frog's heart by inhibitory nerve impulses.	Nature	1955	https://conductscience.org/library/papers/14394097	PubMed
10	200,739	Synaptic excitation and inhibition resulting from direct action of acetylcholine on two types of chemoreceptors on individual amphibian parasympathetic neurones.	J Physiol	1977	https://conductscience.org/library/papers/200739	PubMed
11	303,699	Membrane currents underlying activity in frog sinus venosus.	J Physiol	1977	https://conductscience.org/library/papers/303699	PubMed
12	839,456	The regulation of the calcium conductance of cardiac muscle by adrenaline.	J Physiol	1977	https://conductscience.org/library/papers/839456	PubMed
13	194,028	Microiontophoretic studies of the effects of cylic nucleotides on excitability of neurones in the rat cerebral cortex.	J Physiol	1977	https://conductscience.org/library/papers/194028	PubMed
14	21,550	Cyclic AMP and contractile activity in heart.	Adv Cyclic Nucleotide Res	1977	https://conductscience.org/library/papers/21550	PubMed

1 to 10 of 49

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Cited by33

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 111 citations.

PMID	Title	Journal	Year	In Papers	Source
38,873,876	Publication guidelines for human heart rate and heart rate variability studies in psychophysiology-Part 1: Physiological underpinnings and foundations of measurement.	Psychophysiology	2024	https://conductscience.org/library/papers/38873876	PubMed
34,640,590	Is the Sympathetic System Detrimental in the Setting of Septic Shock, with Antihypertensive Agents as a Counterintuitive Approach? A Clinical Proposition.	J Clin Med	2021	https://conductscience.org/library/papers/34640590	PubMed
31,028,266	Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies.	Nat Commun	2019	https://conductscience.org/library/papers/31028266	PubMed
23,357,106	Abundance, distribution, mobility and oligomeric state of M₂ muscarinic acetylcholine receptors in live cardiac muscle.	J Mol Cell Cardiol	2013	https://conductscience.org/library/papers/23357106	PubMed
7,965,847	Ionophoretically applied acetylcholine and vagal stimulation in the arrested sinus venosus of the toad, Bufo marinus.	J Physiol	1994	https://conductscience.org/library/papers/7965847	PubMed
7,680,074	Membrane-delimited cell signaling complexes: direct ion channel regulation by G proteins.	J Membr Biol	1993	https://conductscience.org/library/papers/7680074	PubMed
7,338,810	Ion diffusion modified by tortuosity and volume fraction in the extracellular microenvironment of the rat cerebellum.	J Physiol	1981	https://conductscience.org/library/papers/7338810	PubMed
7,182,463	Muscarinic agonists inactivate potassium conductance of guinea-pig myenteric neurones.	J Physiol	1982	https://conductscience.org/library/papers/7182463	PubMed
7,131,311	Cholinergic and catecholaminergic receptors in the Xenopus oocyte membrane.	J Physiol	1982	https://conductscience.org/library/papers/7131311	PubMed
7,108,802	Membrane potential responses of the mouse anococcygeus muscle to ionophoretically applied noradrenaline.	J Physiol	1982	https://conductscience.org/library/papers/7108802	PubMed

1 to 10 of 33

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Genes0

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None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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